How the co-integration analysis can help in mortality forecasting. [PDF]
series of age-specific log-mortality rates as a sum of an independent of time age-specific component and a bilinear term in which one of the component is a time-varying parameter reflecting general change in mortality and the second one is an age ...
Darkiewicz, Grzegorz, Hoedemakers, Tom
core
Coherent Mortality Forecasting for the Algerian Population
, 2021 Mortality forecasting is much needed for population projections and actuarial calculations. Forecasting mortality of males and females in an independent way leads in most of cases to some incoherence regarding the expected male-female mortality evolution.
Flici, Farid, Farid Flici
core +1 more source
Mortality Forecasting Using Variational Inference
Journal of ForecastingABSTRACT This paper considers the problem of forecasting mortality rates. A large number of models have already been proposed for this task, but they generally have the disadvantage of either estimating the model in a two‐step process, possibly losing efficiency, or relying on methods that are cumbersome for the ...
Patrik Andersson, Mathias Lindholm
openaire +3 more sources
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Variance in Death and Its Implications for Modeling and Forecasting Mortality [PDF]
Entropy, or the gradual decline through age in the survivorship function, reflects the considerable amount of variance in length of life found in any human population.
Ryan D. Edwards, Shripad Tuljapurkar
core
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Point and interval forecasts of mortality rates and life expectancy: A comparison of ten principal component methods [PDF]
Using the age- and sex-specific data of 14 developed countries, we compare the point and interval forecast accuracy and bias of ten principal component methods for forecasting mortality rates and life expectancy.
Heather Booth +2 more
core
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Stochastic population forecasts using functional data models for mortality, fertility and migration [PDF]
Age-sex-specific population forecasts are derived through stochastic population renewal using forecasts of mortality, fertility and net migration. Functional data models with time series coefficients are used to model age-specific mortality and fertility
Heather Booth, Rob J Hyndman
core
Predictive performance of international COVID-19 mortality forecasting models. [PDF]
Nat Commun, 2021 Friedman J +12 more
europepmc +1 more source