Results 61 to 70 of about 110,803 (293)

A NEURAL-NETWORK ANALYZER FOR MORTALITY FORECAST [PDF]

ASTIN Bulletin, 2018
AbstractThis article proposes a neural-network approach to predict and simulate human mortality rates. This semi-parametric model is capable to detect and duplicate non-linearities observed in the evolution of log-forces of mortality. The method proceeds in two steps.
openaire   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Global burden of cardiovascular diseases attributable to diet low in vegetables from 1990 to 2021 and forecasting the future trends: a population-based study

Frontiers in Cardiovascular Medicine
BackgroundThis investigation examines the worldwide impact of cardiovascular diseases (CVD) resulting from inadequate vegetable consumption, based on the 2021 Global Burden of Disease Study data.MethodThe study assessed the global, regional, and national
Qingsong Mao, Yuzhe Kong
doaj   +1 more source

Forecasting Mortality Rate by Singular Spectrum Analysis

Revstat Statistical Journal, 2015
Singular spectrum analysis (SSA) is a relatively new and powerful non-parametric time series analysis technique that has demonstrated its capability in forecasting different time series in various disciplines.
Rahim Mahmoudvand , Fatemeh Alehosseini , Paulo Canas Rodrigues   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Analysis of chronic kidney disease epidemiology in Kazakhstan using nationwide data for 2014–2020 and forecasting future trends of prevalence and mortality for 2030

Renal Failure
According to the Global Burden of Disease (GBD) study, chronic kidney disease (CKD) was prevalent in 697.5 million individuals worldwide in 2017. By 2040, it is anticipated that CKD will rank as the fifth most common cause of death.
Gulnur Zhakhina, Kamilla Mussina, Sauran Yerdessov, Arnur Gusmanov, Yesbolat Sakko, Valdemir Kim, Dmitriy Syssoyev, Meruyert Madikenova, Ainur Assan, Zhanat Kuanshaliyeva, Duman Turebekov, Kuanysh Yergaliyev, Bolat Bekishev, Abduzhappar Gaipov   +13 more
doaj   +1 more source

Results from the centers for disease control and prevention's predict the 2013-2014 Influenza Season Challenge [PDF]

, 2016
Background: Early insights into the timing of the start, peak, and intensity of the influenza season could be useful in planning influenza prevention and control activities.
Allen, Christopher, Alper, David, Aman, Susan, Anil Kumar, V. S., Aslam, Anoshã, Bakach, Iurii, Barrett, Chris, BASAGNI, Stefano, Biggerstaff, Matthew, Bisset, Keith, Broniatowski, David, Brooks, Logan, Brownstein, John S., Butler, Patrick, Chakraborty, Prithwish, Chandra, Priyadarshini, Chen, Jiangzhuo, Del Valle, Sara Y., Deshpande, Alina, Dredze, Mark, Eggo, Rosalind, Eubank, Stephen, Fairchild, Geoffrey, Farrow, David, Finelli, Lyn, Fox, Spencer, Fung, Isaac Chun Hai, Gambhir, Manoj, Generous, Nicholas, GESUALDO, Francesco, Goldstein, Ed, Hao, Yi, Henderson, Jette, Hickman, Kyle S., Hickmann, Kyle S., Hyman, James M., Hyun, Sangwon, Karspeck, Alicia, Kaup, Hemchandra, Khadivi, Pejman, Krishnan, Ramesh, Laskowski, Kathy, Lewis, Bryan, Lipsitch, Marc, Lum, Kristian, Madhavan, Satish, Marathe, Madhav, Markar, Ashirwad, Mekaru, Sumiko R., Meyers, Lauren Ancel, Nagel, Anna, Nsoesie, Elaine O., Pashley, Bryanne, Paul, Michael, PERRA, NICOLA, Priedhorsky, Reid, Ramakrishnan, Anurekha, Ramakrishnan, Naren, Rosenfeld, Roni, Scarpino, Sam, Schaible, Braydon J., Scott, James, Sexton, Jessica K., Shaman, Jeffrey, Singh, Bismark, Srinivasan, Ravi, STILO, GIOVANNI, Tibshirani, Ryan J., Tozzi, Alberto E., Tse, Zion Tsz Ho, Tsou, Ming Hsiang, VELARDI, Paola, Vespignani, Alessandro, Yang, Wan, Ying, Yuchen, Zhang, Qian   +75 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Global burden of pneumoconiosis attributable to occupational particulate matter, gasses, and fumes from 1990~2021 and forecasting the future trends: a population-based study

Frontiers in Public Health
BackgroundThis study aimed to quantify the global impact of pneumoconiosis resulting from occupational exposure to particulate matter, gasses, and fumes from 1990 to 2021, utilizing data from the Global Burden of Disease Study 2021.MethodThe analysis ...
Mao Qingsong, Ruijie Xiao, Wenqi Yang, Xinyi Wang, Yu-zhe Kong   +4 more
doaj   +1 more source

Identifiability issues of age-period and age-period-cohort models of the Lee-Carter type

, 2016
The predominant way of modelling mortality rates is the Lee-Carter model and its many extensions. The Lee-Carter model and its many extensions use a latent process to forecast.
Beutner, Eric, Reese, Simon, Urbain, Jean-Pierre   +2 more
core   +2 more sources