Results 61 to 70 of about 1,724,016 (262)
FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Non mean reverting affne processes for stochastic mortality [PDF]
In this paper we use doubly stochastic processes (or Cox processes) in order to model the random evolution of mortality of an individual. These processes have been widely used in the credit risk literature in modelling default arrival, and in this ...
Elisa Luciano, Elena Vigna
core
Forecasting mortality using Google trend
CoRR, 2019 9 pages, 3 figures, 2 ...
openaire +2 more sources
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Forecasting age-related changes in breast cancer mortality among white and black US women: A functional approach [PDF]
The disparity in breast cancer mortality rates among white and black US women is widening with higher mortality rates among black women. We apply functional time series models on age-specific breast cancer mortality rates for each group of women, and ...
Farah Yasmeen +2 more
core
Smooth constrained mortality forecasting
, 2019 Background: Mortality can be forecast by means of parametric models, principal component methods, and smoothing approaches. These methods either impose rigid modeling structures or produce implausible outcomes. Objective: We propose a novel approach for
Camarda, Carlo Giovanni
core +1 more source
Mortality forecasting with ensembles and combinations
, 2023 Many alternative approaches for selecting mortality models and calibration periods have been proposed. The usual practice is to base forecasts on a single mortality model se- lected using in-sample goodness-of-fit measures and an arbitrarily chosen calibration period.
openaire +2 more sources
Mortality Forecasting with the Lee-Carter Method: Adjusting for Smoothing and Lifespan Disparity. [PDF]
Eur J Popul, 2021 Rabbi AMF, Mazzuco S.
europepmc +1 more source
Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source