Results 81 to 90 of about 1,795,685 (335)

Chemoenzymatic Probes for Detecting and Imaging Fucose-α(1-2)-galactose Glycan Biomarkers [PDF]

, 2012
The disaccharide motif fucose-α(1-2)-galactose (Fucα(1-2)Gal) is involved in many important physiological processes, such as learning and memory, inflammation, asthma, and tumorigenesis.
Becker D. J., Blixt O., Blixt O., Chang C.-F., Chang W.-W., Chithra Krishnamurthy, Clark P. M., David F. Smith, Delves P. J., Hanson S. R., Jean-Luc Chaubard, Khidekel N., Kim Y., Laughlin S. T., Lee J. S., Linda C. Hsieh-Wilson, Manimala J. C., Manimala J. C., Miyake M., Murrey H. E., Murrey H. E., Peracaula R., Pohle W., Rexach J. E., Schröder F. H., Tanaka Y., Tiunova A. A., Wen Yi, Yi W., Zhang S., Zheng T.   +30 more
core   +3 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Automated DNA Motif Discovery [PDF]

, 2010
Ensembl's human non-coding and protein coding genes are used to automatically find DNA pattern motifs. The Backus-Naur form (BNF) grammar for regular expressions (RE) is used by genetic programming to ensure the generated strings are legal.
Graillet, Olivia Sanchez, Harrison, A. P., Langdon, W. B.   +2 more
core   +2 more sources

Chiral properties of hematite ({\alpha}-Fe2O3) inferred from resonant Bragg diffraction using circularly polarized x-rays

, 2013
Chiral properties of the two phases - collinear motif (below Morin transition temperature, TM=250 K) and canted motif (above TM) - of magnetically ordered hematite ({\alpha}-Fe2O3) have been identified in single crystal resonant x-ray Bragg diffraction ...
Blanco, J. A., Lovesey, S. W., Rodriguez-Fernandez, A., Scagnoli, V., Shukla, D. K., Staub, U., Strempfer, J., Walker5, H. C.   +7 more
core   +1 more source

The eukaryotic linear motif resource – 2018 update

Nucleic Acids Res., 2017
Short linear motifs (SLiMs) are protein binding modules that play major roles in almost all cellular processes. SLiMs are short, often highly degenerate, difficult to characterize and hard to detect. The eukaryotic linear motif (ELM) resource (elm.eu.org)
Marc Gouw, S. Michael, Hugo Sámano-Sánchez, Manjeet Kumar, A. Zeke, Benjamin Lang, B. Bely, L. Chemes, Norman E. Davey, Ziqi Deng, F. Diella, Clara-Marie Gürth, Ann-Kathrin Huber, Stefan Kleinsorg, Lara S. Schlegel, Nicolás Palopoli, K. Roey, B. Altenberg, A. Reményi, Holger Dinkel, T. Gibson   +20 more
semanticscholar   +1 more source

Scalable Motif-aware Graph Clustering [PDF]

The Web Conference, 2016
We develop new methods based on graph motifs for graph clustering, allowing more efficient detection of communities within networks. We focus on triangles within graphs, but our techniques extend to other clique motifs as well.
Charalampos E. Tsourakakis, J. Pachocki, M. Mitzenmacher   +2 more
semanticscholar   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Motif of "AbuzarGhaffari" in Yahyaal-Samawy’s Poetry [PDF]

پژوهش‌های ترجمه در زبان و ادبیات عربی, 2012
As one of the important elements in literary critisism and analysis, motif is taken into consideration in European criticism. Originally as a French word, motif means the main thought or the subject or the iterative words and phrases in literature.
Marzieh Abad, Rasol Ballavi
doaj   +1 more source

Identification of multiple genomic DNA sequences which form i-motif structures at neutral pH

Nucleic Acids Research, 2017
i-Motifs are alternative DNA secondary structures formed in cytosine-rich sequences. Particular examples of these structures, traditionally assumed to be stable only at acidic pH, have been found to form under near-physiological conditions.
Elisé P. Wright, J. Huppert, Zoë A. E. Waller   +2 more
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source