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Highly motile nanoscale magnetic artificial cilia [PDF]
Proceedings of the National Academy of Sciences, 2021 Significance Cilia are hair-like microscopic structures present abundantly in our body and producing motions at the smallest scales. They perform a wide range of critical functions and are crucial for the normal functioning of our body.
Islam, Tanveer ul +2 more
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IFT74 variants cause skeletal ciliopathy and motile cilia defects in mice and humans.
PLoS Genetics, 2023 Motile and non-motile cilia play critical roles in mammalian development and health. These organelles are composed of a 1000 or more unique proteins, but their assembly depends entirely on proteins synthesized in the cell body and transported into the ...
Zeineb Bakey +25 more
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Scientific Reports, 2021 Cilia are protrusions of the cell surface and composed of hundreds of proteins many of which are evolutionary and functionally well conserved. In cells assembling motile cilia the expression of numerous ciliary components is under the control of the ...
Anja Beckers +14 more
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The regulatory roles of motile cilia in CSF circulation and hydrocephalus
Fluids and Barriers of the CNS, 2021 Background Cerebrospinal fluid (CSF) is an ultra-filtrated colorless brain fluid that circulates within brain spaces like the ventricular cavities, subarachnoid space, and the spine.
Vijay Kumar +5 more
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Cell, 2015 Motile cilia are hair-like organelles that protrude from the cell surface and are conserved throughout eukaryotes. Motile cilia beat rhythmically and function in cellular and organismal locomotion and in driving fluid transport over epithelia. In vertebrates, their roles are varied, and their dysfunction in humans is associated with disease.
Zhou, Feng, Roy, Sudipto
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PLoS Genetics, 2012 It is generally believed that the last eukaryotic common ancestor (LECA) was a unicellular organism with motile cilia. In the vertebrates, the winged-helix transcription factor FoxJ1 functions as the master regulator of motile cilia biogenesis.
Shubha Vij +9 more
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Purification and Immunostaining of Mouse Ependymal Ciliary Shafts
Bio-Protocol, 2022 Cilia and flagella are microtubule-based hair-like organelles protruding from the surface of most eukaryotic cells, and play essential roles in cell locomotion, left-right asymmetry, embryo development, and tissue homeostasis.
Kai Hao, Xueliang Zhu , Xiumin Yan
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Mutation of Growth Arrest Specific 8 Reveals a Role in Motile Cilia Function and Human Disease. [PDF]
PLoS Genetics, 2016 Ciliopathies are genetic disorders arising from dysfunction of microtubule-based cellular appendages called cilia. Different cilia types possess distinct stereotypic microtubule doublet arrangements with non-motile or 'primary' cilia having a 9+0 and ...
Wesley R Lewis +20 more
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Frontiers in Cellular Neuroscience, 2019 In the adult mammalian brain, the apical surface of the subependymal zone (SEZ) is covered by many motile ependymal cilia and a few primary cilia originating from rare intermingled neural stem cells (NSCs).
Sara Monaco +5 more
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, 2023 This data includes XL/MS and structural models for the Tetrahymena motile cilia interactome.
Caitlyn L. McCafferty +6 more
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