Results 31 to 40 of about 89,658 (280)

Zebrafish Motile Cilia as a Model for Primary Ciliary Dyskinesia [PDF]

Int J Mol Sci, 2021
Zebrafish is a vertebrate teleost widely used in many areas of research. As embryos, they develop quickly and provide unique opportunities for research studies owing to their transparency for at least 48 h post fertilization. Zebrafish have many ciliated
Andreia L. Pinto, Margarida Rasteiro, Catarina Bota, Sara Pestana, P. Sampaio, C. Hogg, T. Burgoyne, Susana S. Lopes   +7 more
semanticscholar   +2 more sources

Ion channels and calcium signaling in motile cilia

eLife, 2015
The beating of motile cilia generates fluid flow over epithelia in brain ventricles, airways, and Fallopian tubes. Here, we patch clamp single motile cilia of mammalian ependymal cells and examine their potential function as a calcium signaling ...
Julia F Doerner, Markus Delling, David E Clapham   +2 more
doaj   +4 more sources

Motile cilia of the male reproductive system require miR-34/miR-449 for development and function to generate luminal turbulence [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Motile cilia are found lining the respiratory and reproductive systems, as well as the brain and spinal column, and the coordinated beat moves fluids over the luminal surfaces.
Shuiqiao Yuan, Yue Liu, Hongying Peng, Chong Tang, Grant W. Hennig, Zhuqing Wang, Li Wang, Tian Yu, Rachel Klukovich, Ying Zhang, Huili Zheng, Xu Chen, Jingwen Wu, Rex A. Hess, Wei Yan   +14 more
openalex   +2 more sources

Exploring mechanisms of ventricular enlargement in idiopathic normal pressure hydrocephalus: a role of cerebrospinal fluid dynamics and motile cilia [PDF]

Fluids Barriers CNS, 2021
Idiopathic normal pressure hydrocephalus (iNPH) is considered an age-dependent chronic communicating hydrocephalus associated with cerebrospinal fluid (CSF) malabsorption; however, the aetiology of ventricular enlargement in iNPH has not yet been ...
S. Yamada, M. Ishikawa, K. Nozaki
semanticscholar   +2 more sources

Electrical Signaling in Motile and Primary Cilia

BioScience, 2014
Cilia are highly conserved for their structure and also for their sensory functions. They serve as antennae for extracellular information. Whether the cilia are motile or not, they respond to environmental mechanical and chemical stimuli and signal to the cell body.
Steven J. Kleene, Judith L. Van Houten
openalex   +4 more sources

Entrainment of mammalian motile cilia in the brain with hydrodynamic forces [PDF]

Proc Natl Acad Sci U S A, 2020
Significance We determine, in multiciliated mammalian cells, conditions for oscillatory flow to entrain brain motile cilia: Hydrodynamic forces of magnitude comparable to those generated by cilia themselves are sufficient to establish coordinated ...
Nicola Pellicciotta, Evelyn Hamilton, J. Kotar, Marion Faucourt, N. Delgehyr, N. Spassky, P. Cicuta   +6 more
semanticscholar   +2 more sources

Cilia in the choroid plexus: their roles in hydrocephalus and beyond [PDF]

Frontiers in Cellular Neuroscience, 2015
Cilia are whip-like projections that are widely conserved in eukaryotes and function as a motile propeller and/or sensory platform to detect various extracellular stimuli. In vertebrates, cilia are ubiquitously found in most cells, showing structural and
Keishi eNarita, Sen eTakeda
doaj   +3 more sources

Computational Modeling of Motile Cilia-Driven Cerebrospinal Flow in the Brain Ventricles of Zebrafish Embryo [PDF]

Bioengineering, 2022
Motile cilia are hair-like microscopic structures which generate directional flow to provide fluid transport in various biological processes. Ciliary beating is one of the sources of cerebrospinal flow (CSF) in brain ventricles.
Huseyin Enes Salman, Nathalie Jurisch-Yaksi, Huseyin Cagatay Yalcin   +2 more
doaj   +2 more sources

Proliferation associated 2G4 is required for the ciliation of vertebrate motile cilia [PDF]

Communications Biology
Motile cilia are critical structures that regulate early embryonic development and tissue homeostasis through synchronized ciliary motility. The formation of motile cilia is dependent on precisely controlled sequential processes including the generation,
Moonsup Lee, Christina Carpenter, Yoo-Seok Hwang, Jaeho Yoon, Quanlong Lu, Christopher J. Westlake, Sally A. Moody, Terry P. Yamaguchi, Ira O. Daar   +8 more
doaj   +2 more sources

Dynein assembly factor with WD repeat domains 1 (DAW1) is required for the function of motile cilia in the planarian Schmidtea mediterranea

Development, Growth and Differentiation, 2020
Motile cilia propel directed cell movements and sweep fluids across the surface of tissues. Orthologs of Dynein Assembly Factor with WD Repeat Domains 1 (DAW1) support normal ciliary beating by enhancing delivery of dynein complexes to axonemal ...
Sydney L. Lesko, Labib Rouhana
openalex   +3 more sources