Ciliary contact interactions dominate surface scattering of swimming eukaryotes [PDF]
Proc. Natl. Acad. Sci. U.S.A. 110(4), 1187-1192 (2013), 2012 Interactions between swimming cells and surfaces are essential to many microbiological processes, from bacterial biofilm formation to human fertilization.
Dunkel, Jörn +3 more
core +2 more sources
LRRC6 regulates biogenesis of motile cilia by aiding FOXJ1 translocation into the nucleus. [PDF]
Cell Commun Signal, 2023 Background LRRC6 is an assembly factor for dynein arms in the cytoplasm of motile ciliated cells, and when mutated, dynein arm components remained in the cytoplasm.
Kim DY +8 more
europepmc +2 more sources
Cilia in the choroid plexus: their roles in hydrocephalus and beyond [PDF]
Frontiers in Cellular Neuroscience, 2015 Cilia are whip-like projections that are widely conserved in eukaryotes and function as a motile propeller and/or sensory platform to detect various extracellular stimuli. In vertebrates, cilia are ubiquitously found in most cells, showing structural and
Keishi Narita, Sen Takeda
core +4 more sources
Chlamydomonas DYX1C1/PF23 is essential for axonemal assembly and proper morphology of inner dynein arms [PDF]
PLoS Genetics, 2017 Cytoplasmic assembly of ciliary dyneins, a process known as preassembly, requires numerous non-dynein proteins, but the identities and functions of these proteins are not fully elucidated.
Alford, Lea M +12 more
core +14 more sources
Motile Cilia: Innovation and Insight From Ciliate Model Organisms. [PDF]
Front Cell Dev Biol, 2019 Ciliates are a powerful model organism for the study of basal bodies and motile cilia. These single-celled protists contain hundreds of cilia organized in an array making them an ideal system for both light and electron microscopy studies.
Bayless BA, Navarro FM, Winey M.
europepmc +3 more sources
IFT74variants cause skeletal ciliopathy and motile cilia defects in mice and humans [PDF]
medRxiv, 2023 Zeineb Bakey +25 more
openalex +2 more sources
TGF-β Signaling Regulates the Differentiation of Motile Cilia [PDF]
Cell Reports, 2015 The cilium is a small cellular organelle with motility- and/or sensory-related functions that plays a crucial role during developmental and homeostatic processes. Although many molecules or signal transduction pathways that control cilia assembly have been reported, the mechanisms of ciliary length control have remained enigmatic.
Jacob Brown +8 more
openaire +5 more sources
Oviductal motile cilia are essential for oocyte pickup but dispensable for sperm and embryo transport. [PDF]
Proc Natl Acad Sci U S A, 2021 Significance The oviduct is essential for female fertility due to its two main functions: transport and nourishment. While the nourishment role is mainly fulfilled by secretory cells, the relative contribution to the transport function by ciliated cells ...
Yuan S +6 more
europepmc +2 more sources
ARL13B controls male reproductive tract physiology through primary and Motile Cilia. [PDF]
Commun BiolARL13B is a small regulatory GTPase that controls ciliary membrane composition in both motile cilia and non-motile primary cilia. In this study, we investigated the role of ARL13B in the efferent ductules, tubules of the male reproductive tract essential
Augière C +13 more
europepmc +2 more sources
Exploring mechanisms of ventricular enlargement in idiopathic normal pressure hydrocephalus: a role of cerebrospinal fluid dynamics and motile cilia. [PDF]
Fluids Barriers CNS, 2021 Idiopathic normal pressure hydrocephalus (iNPH) is considered an age-dependent chronic communicating hydrocephalus associated with cerebrospinal fluid (CSF) malabsorption; however, the aetiology of ventricular enlargement in iNPH has not yet been ...
Yamada S, Ishikawa M, Nozaki K.
europepmc +2 more sources