Results 21 to 30 of about 2,514,411 (397)
Distinct Corticostriatal GABAergic Neurons Modulate Striatal Output Neurons and Motor Activity
Cell Reports, 2017 Summary: The motor cortico-basal ganglion loop is critical for motor planning, execution, and learning. Balanced excitation and inhibition in this loop is crucial for proper motor output.
Sarah Melzer +5 more
doaj +1 more source
Journal of Physiology, 2019 We propose and validate a method for accurately identifying the activity of populations of motor neurons during contractions at maximal rate of force development in humans.
A. Del Vecchio +6 more
semanticscholar +1 more source
Theranostics, 2019 Recent studies have demonstrated that bone marrow mesenchymal stem cells (BMSCs) protect the injured neurons of spinal cord injury (SCI) from apoptosis while the underlying mechanism of the protective effect of BMSCs remains unclear.
Heyangzi Li +7 more
semanticscholar +1 more source
Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. [PDF]
PLoS ONE, 2015 Cell adhesion molecules belonging to the immunoglobulin superfamily (IgSF) control synaptic specificity through hetero- or homophilic interactions in different regions of the nervous system.
Zirong Gu +7 more
doaj +1 more source
Determining monkey free choice long before the choice is made: the principal role of prefrontal neurons involved in both decision and motor processes [PDF]
, 2016 When choices are made freely, they might emerge from pre-existing neural activity. However, whether neurons in the prefrontal cortex (PF) show this anticipatory effect and, if so, in which part of the process they are involved is still debated. To answer
Genovesio, Aldo, Marcos, Encarni
core +2 more sources
PLoS Biology, 2022 The ability of terrestrial vertebrates to effectively move on land is integrally linked to the diversification of motor neurons into types that generate muscle force (alpha motor neurons) and types that modulate muscle proprioception, a task that in ...
Mudassar N Khan +14 more
doaj +1 more source
Large-scale Spatiotemporal Spike Patterning Consistent with Wave Propagation in Motor Cortex [PDF]
, 2015 Aggregate signals in cortex are known to be spatiotemporally organized as propagating waves across the cortical surface, but it remains unclear whether the same is true for spiking activity in individual neurons.
Best, Matthew D. +6 more
core +2 more sources
FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons
Nature Communications, 2017 The RNA-binding protein FUS participates in several RNA biosynthetic processes and has been linked to the pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. Here we report that FUS controls back-splicing reactions leading to
Lorenzo Errichelli +14 more
semanticscholar +1 more source
Postgraduate Medical Journal, 2002 Abstract Motor neurone disease (MND), or amyotrophic lateral sclerosis (ALS), is a neurodegenerative disorder of unknown aetiology. Progressive motor weakness and bulbar dysfunction lead to premature death, usually from respiratory failure. Confirming the diagnosis may initially be difficult until the full clinical features are manifest.
openaire +3 more sources
Disease Models & Mechanisms, 2016 Spinal muscular atrophy (SMA), characterized by specific degeneration of spinal motor neurons, is caused by mutations in the survival of motor neuron 1, telomeric (SMN1) gene and subsequent decreased levels of functional SMN. How the deficiency of SMN, a
Chong-Chong Xu +4 more
doaj +1 more source