Results 201 to 210 of about 722,567 (342)

Kinesin-like motor protein KIF23 maintains neural stem and progenitor cell pools in the developing cortex. [PDF]

EMBO J
Naher S, Iemura K, Miyashita S, Hoshino M, Tanaka K, Niwa S, Tsai JW, Kikkawa T, Osumi N.   +8 more
europepmc   +1 more source

How the double-ring ClpAP protease motor grips the substrate to unfold and degrade stable proteins [PDF]

T. Shane Shih, Robert T. Sauer, Tania A. Baker   +2 more
openalex   +1 more source

Non-native, N-terminal Hsp70 Molecular Motor Recognition Elements in Transit Peptides Support Plastid Protein Translocation [PDF]

, 2015
Prakitchai Chotewutmontri, Barry D. Bruce   +1 more
openalex   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Hydroxyapatite microspheres encapsulated within hybrid hydrogel promote skin regeneration through the activation of Calcium Signaling and Motor Protein pathway. [PDF]

Bioact Mater
Liu S, Song L, Huang S, Liu Z, Xu Y, Wang Z, Qiu H, Wang J, Chen Z, Xiao Y, Wang H, Zhu X, Zhang K, Zhang X, Lin H.   +14 more
europepmc   +1 more source

Direct observation of motor protein stepping in living cells using MINFLUX

, 2022
Deguchi T, Iwanski MK, Schentarra E, Heidebrecht C, Schmidt L, Heck J, Weihs T, Schnorrenberg S, Hoess P, Liu S, Chevyreva V, Noh K, Kapitein LC, Ries J.   +13 more
europepmc   +1 more source

Author response: Stereotyped terminal axon branching of leg motor neurons mediated by IgSF proteins DIP-α and Dpr10

, 2019
Lalanti Venkatasubramanian, Zhenhao Guo, Shuwa Xu, Liming Tan, Qi Xiao, Sonal Nagarkar-Jaiswal, Richard S. Mann   +6 more
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Motor protein KIF13B orchestrates hepatic metabolism to prevent metabolic dysfunction-associated fatty liver disease. [PDF]

Mil Med Res
Miao GL, Zhang WX, Xu YT, Liu YR, Lai PP, Guo JB, Chen GL, Chen JX, Zhou ZH, Li YW, Zhang C, Ding Y, Zhang LX, Han YF, Chen JX, Wu JD, Zhao YQ, Mei S, Zhao Y, Ma YW, Zhang L, Huang W, Zhao DY, Dong ED, Wang YH, Xian XD.   +25 more
europepmc   +1 more source

MOESM11 of Salivary gland proteome analysis of developing adult female Haemaphysalis longicornis ticks: molecular motor and TCA cycle-related proteins play an important role throughout development

, 2019
Shuguang Ren, Baowen Zhang, Xiaomin Xue, Xiaoshuang Wang, Huaqu Zhao, Xiaoli Zhang, Minjing Wang, Qi Xiao, Hui Wang, Jingze Liu   +9 more
openalex   +1 more source