Results 61 to 70 of about 498,521 (337)

Life without double-headed non-muscle myosin II motor proteins

Frontiers in Chemistry, 2014
Non-muscle myosin II motor proteins (myosin IIA, myosin IIB, and myosin IIC) belong to a class of molecular motor proteins that are known to transduce cellular free-energy into biological work more efficiently than man-made combustion engines. Nature has
Venkaiah eBetapudi
doaj   +1 more source

IFNγ protects motor neurons from oxidative stress via enhanced global protein synthesis in FUS ‐associated amyotrophic lateral sclerosis [PDF]

, 2023
Amanda F. Assoni, Erika N. Guerrero, René Wardenaar, Danyllo Oliveira, Petra L. Bakker, Luciana Moura Alves, Valdemir Melechco Carvalho, Oswaldo Keith Okamoto, Mayana Zatz, Floris Foijer   +9 more
openalex   +1 more source

Enhanced reaction kinetics in biological cells

, 2008
The cell cytoskeleton is a striking example of "active" medium driven out-of-equilibrium by ATP hydrolysis. Such activity has been shown recently to have a spectacular impact on the mechanical and rheological properties of the cellular medium, as well as
A Ajdari, B Alberts, C Storm, C. Loverdo, D Holcman, D Mizuno, F Nedelec, FJ Nedelec, G Kolesov, H Salman, I Eliazar, J Howard, K Kruse, L Le Goff, M Coppey, M Slutsky, M. Moreau, MA Lomholt, MF Shlesinger, MF Shlesinger, MP Sheetz, O Berg, O Bénichou, O Bénichou, O Bénichou, O Thoumine, O. Bénichou, P Dalhaimer, R Voituriez, R Voituriez, R. Voituriez, S Condamin, S Huet, S Redner   +33 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Mitochondrial Proteins Unveil the Mechanism by Which Physical Exercise Ameliorates Memory, Learning and Motor Activity in Hypoxic Ischemic Encephalopathy Rat Model [PDF]

, 2022
Fred Gendi, Feifei Pei, Yuan Wang, Haoye Li, Jia Fu, Cheng Chang   +5 more
openalex   +1 more source

Understanding Mechanochemical Coupling in Kinesins Using First-Passage Time Processes

, 2004
Kinesins are processive motor proteins that move along microtubules in a stepwise manner, and their motion is powered by the hydrolysis of ATP. Recent experiments have investigated the coupling between the individual steps of single kinesin molecules and
A. B. Kolomeisky, A. B. Kolomeisky, A. Yildiz, Alex A. Popov, Anatoly B. Kolomeisky, D. Bray, Evgeny B. Stukalin, H. Lodish, J. Howard, K. Svoboda, M. E. Fisher, N. G. van Kampen   +11 more
core   +1 more source

Letter to the editor: autoimmune pathogenic mechanisms in amyotrophic lateral sclerosis [PDF]

, 2018
The innate immune system may affect the function and survival of motor neurons in ALS by at least three mechanisms. First, there is evidence to suggest that aggregates of mutant SOD1—which is derived from microglial and astroglial cells—activate ...
de Vincentiis, M., De Virgilio, A., Gallo, A., Greco, A., Inghilleri, M., Ralli, M.   +5 more
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

The role of motor proteins in endosomal sorting [PDF]

, 2011
Microtubule motor proteins play key roles in the spatial organization of intracellular organelles as well as the transfer of material between them.
Hunt, Sylvie, Stephens, DJ
core   +2 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source