Results 21 to 30 of about 819,058 (310)

Relation of Apathy to Motor and Non-motor Findings in Parkinson’s Disease

open access: yesHaseki Tıp Bülteni, 2019
Aim:It has been shown that motor symptoms, as well as non-motor symptoms, significantly affect the quality of life of patients with idiopathic Parkinson’s disease. In our study, the association of apathy, one of the NMS, with motor and non-motor symptoms
Melek Gürbüz   +5 more
doaj   +1 more source

Ambulatory Monitoring of Activities and Motor Symptoms in Parkinson's Disease [PDF]

open access: yes, 2010
Ambulatory monitoring of motor symptoms in Parkinson's disease (PD) can improve our therapeutic strategies, especially in patients with motor fluctuations. Previously published monitors usually assess only one or a few basic aspects of the cardinal motor
Geelen, Jan A.G.   +4 more
core   +2 more sources

Fatigue in patients with Parkinson’s disease: Motor and Non-motor Clinical Associations

open access: yesAnkara Üniversitesi Tıp Fakültesi Mecmuası, 2017
Objective: Fatigue is one of the common non-motor symptoms of Parkinson’s disease (PD). In this study, we aimed to investigate the prevalence of fatigue in PD patients and to determine the fatigue-related demographic, motor and non-motor disease ...
Bilge Gönenli Koçer   +2 more
doaj   +1 more source

Sleep quality in patients with Parkinson’s disease in the Republic of Moldova – preliminary results [PDF]

open access: yesRomanian Journal of Neurology
Background and objectives. The rising prevalence of sleep issues are a consequent societal problem, notably impacting individuals with Parkinson’s disease (PD).
Lilia Rotaru   +9 more
doaj   +1 more source

Impact of SAfinamide on Depressive Symptoms in Parkinson’s Disease Patients (SADness-PD Study): A Multicenter Retrospective Study

open access: yesBrain Sciences, 2021
Background: We aimed to assess the effects of safinamide on depression, motor symptoms, and the serotonin syndrome related to its co-administration with antidepressants in patients with Parkinson’s disease (PD).
Esteban Peña   +11 more
doaj   +1 more source

Emergence of nonmotor symptoms as the focus of research and treatment of Parkinson's disease: Introduction to the special section on nonmotor dysfunctions in Parkinson's disease [PDF]

open access: yes, 2013
Parkinson's disease (PD) is traditionally characterized by the cardinal motor symptoms of tremor, rigidity, slowness of movement, and impairments of posture, gait, and balance.
Cronin-Golomb, Alice
core   +1 more source

The cerebellum and motor dysfunction in neuropsychiatric disorders [PDF]

open access: yes, 2007
The cerebellum is densely interconnected with sensory-motor areas of the cerebral cortex, and in man, the great expansion of the association areas of cerebral cortex is also paralleled by an expansion of the lateral cerebellar hemispheres.
Gowen, Emma, Miall, R. Chris
core   +3 more sources

Progressive Motor and Non-Motor Symptoms in Park7 Knockout Zebrafish

open access: yesInternational Journal of Molecular Sciences, 2023
DJ-1 is a redox sensitive protein with a wide range of functions related to oxidative stress protection. Mutations in the park7 gene, which codes for DJ-1 are associated with early onset familial Parkinson’s disease and increased astrocytic DJ-1 levels are found in pathologic tissues from idiopathic Parkinson’s disease. We have previously established a
Lakshmi Chavali   +8 more
openaire   +4 more sources

Additive Effects of Levodopa and a Neurorestorative Diet in a Mouse Model of Parkinson’s Disease

open access: yesFrontiers in Aging Neuroscience, 2018
Though Parkinson’s disease (PD) clinical picture is generally dominated by motor impairment, non-motor symptoms, such as cognitive decline and gastrointestinal dysfunctions, may develop before motor symptoms and have major effects on quality of life. L-3,
Paula Perez-Pardo   +8 more
doaj   +1 more source

Kinematic analysis of handwriting movements in patients with Alzheimer's disease, mild cognitive impairment, depression and healthy subjects [PDF]

open access: yes, 2003
A variety of studies have demonstrated that motor disorders, parkinsonism and extrapyramidal motor symptoms (EPMS) are common in patients with Alzheimer's disease (AD).
Burger, K.   +5 more
core   +1 more source

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