Results 81 to 90 of about 60,701 (176)

Drug Delivery Systems for Resiquimod to Control Myeloid‐Derived Suppressor Cells in Cancer Immunotherapy

WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 2, March/April 2026.
Myeloid‐derived suppressor cells (MDSCs) are key contributors to cancer immunotherapy failure and major targets in new therapeutic strategies. We highlight therapeutic approaches to counteract their immunosuppressive functions and discuss recent efforts to optimize drug delivery for controlling MDSCs, focusing on resiquimod as a representative drug ...
Yanying He, Yoon Yeo
wiley   +1 more source

Common Spontaneous Tumors and Tumor-like Lesions in 70 Pet Rodents and Negative MMTV Detection in Mammary Tumors

Animals
Compared to the number of studies on the neoplasms of laboratory rodents, fewer studies have focused on spontaneous neoplasms in pet rodents. Notably, the mouse mammary tumor virus (MMTV) is associated with mammary tumors in rodents.
Ya-Mei Chen, Jia-Ling Wu, Wei-Hao Lin
doaj   +1 more source

Treg cells retain stable lineage commitment during pregnancy in mice after late gestation inflammatory challenge

Immunology &Cell Biology, Volume 104, Issue 3, Page 276-311, March 2026.
In this study, we used Foxp3‐fatemapping mice to examine the cell lineage stability of Treg cells in pregnancy. Ex‐Foxp3 cells were identified in gestational tissues. However, Treg cells retained lineage stability with no increased ex‐Foxp3 generation, regardless of inflammatory challenges that induce preterm birth.
Kerrie L Foyle, Ella S Green, Jessie R Walker‐Rogers, Ha M Tran, David M Olson, Lachlan M Moldenhauer, Sarah A Robertson   +6 more
wiley   +1 more source

Involvement of APOBEC3A/B Deletion in Mouse Mammary Tumor Virus (MMTV)-like Positive Human Breast Cancer. [PDF]

Diagnostics (Basel), 2023
de Sousa Pereira N, Vitiello GAF, Amarante MK.   +2 more
europepmc   +1 more source

Mouse Mammary Tumor Virus: New Tumor Virus or Just a Rumor Virus? [PDF]

JNCI Journal of the National Cancer Institute, 2009
W hen German microbiologist Harald zur Hausen, M.D., D.Sc., hypothesized in 1974 that human papillomavirus (HPV) played a central role in causing cervical cancer, few took him seriously. But in 1983 he discovered HPV-16, and a year later, HPV-18 in tumors of cervical cancer patients — findings that led eventually to the first preventive cancer vaccine ...
openaire   +1 more source

Kemiripan Sekuen Mouse Mammary Tumor Virus dengan Human Mammary Tumor Virus pada Kanker Payudara

Jurnal Kedokteran Meditek, 2014
Abstrackhuman breast cancer incidence varied around the world, where the incidence in Asia is lower than western. Different types if mice in both parts of the world suggestive associated with the incidence of human breast cancer, in which M.domesticus the main carrier of virus more widely available in western. Mouse Mammary Tumor Virus (MMTV) is a type
Shintia Christina, Puspita Eka Wuyung
openaire   +1 more source

Dmp1α inhibits HER2/neu-induced mammary tumorigenesis.

PLoS ONE, 2013
Our recent study shows a pivotal role of Dmp1 in quenching hyperproliferative signals from HER2 to the Arf-p53 pathway as a safety mechanism to prevent breast carcinogenesis.
Elizabeth A Fry, Pankaj Taneja, Dejan Maglic, Sinan Zhu, Guangchao Sui, Kazushi Inoue   +5 more
doaj   +1 more source

Deletion of Vβ3⁺CD4⁺ T cells by endogenous mouse mammary tumor virus 3 prevents type 1 diabetes induction by autoreactive CD8⁺ T cells. [PDF]

Proc Natl Acad Sci U S A, 2023
Ye C, Clements SA, Gu W, Geurts AM, Mathews CE, Serreze DV, Chen YG, Driver JP.   +7 more
europepmc   +1 more source

Thermodynamics of unfolding mechanisms of mouse mammary tumor virus pseudoknot from a coarse-grained loop-entropy model. [PDF]

J Biol Phys, 2022
Tang K, Roca J, Chen R, Ansari A, Liang J.   +4 more
europepmc   +1 more source

ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells.

PLoS Biology, 2015
During pregnancy, the ETS transcription factor ELF5 establishes the milk-secreting alveolar cell lineage by driving a cell fate decision of the mammary luminal progenitor cell.
David Gallego-Ortega, Anita Ledger, Daniel L Roden, Andrew M K Law, Astrid Magenau, Zoya Kikhtyak, Christina Cho, Stephanie L Allerdice, Heather J Lee, Fatima Valdes-Mora, David Herrmann, Robert Salomon, Adelaide I J Young, Brian Y Lee, C Marcelo Sergio, Warren Kaplan, Catherine Piggin, James R W Conway, Brian Rabinovich, Ewan K A Millar, Samantha R Oakes, Tatyana Chtanova, Alexander Swarbrick, Matthew J Naylor, Sandra O'Toole, Andrew R Green, Paul Timpson, Julia M W Gee, Ian O Ellis, Susan J Clark, Christopher J Ormandy   +30 more
doaj   +1 more source