Results 41 to 50 of about 9,249 (288)

Preventive efficacy of oral moxidectin at various doses and dosage regimens against macrocyclic lactone-resistant heartworm (Dirofilaria immitis) strains in dogs

Parasites & Vectors, 2019
Background Moxidectin has previously shown limited efficacy (≤ 44.4%) against confirmed macrocyclic lactone (ML)-resistant Dirofilaria immitis strains at 3 µg/kg after single and multiple oral dosages. Three studies were conducted to evaluate higher oral
Tom L. McTier, Robert H. Six, Aleah Pullins, Sara Chapin, Kristina Kryda, Sean P. Mahabir, Debra J. Woods, Steven J. Maeder   +7 more
doaj   +1 more source

Efficacy of orally administered combination of moxidectin, sarolaner and pyrantel (Simparica Trio™) for the prevention of experimental Angiostrongylus vasorum infection in dogs

Parasites & Vectors, 2020
Background Infection with Angiostrongylus vasorum may cause severe clinical disease, even death in dogs, however, due to the often non-specific clinical signs, diagnosis is not always straightforward. Regular prophylactic treatment may offer a safe means
Csilla Becskei, Mirjan Thys, Padraig Doherty, Sean P. Mahabir   +3 more
doaj   +1 more source

Pharmacokinetics of Moxidectin combined with Albendazole or Albendazole plus Diethylcarbamazine for Bancroftian Filariasis

PLoS Neglected Tropical Diseases, 2023
Moxidectin (MOX) is a milbemycin endectocide recently approved by the U.S. FDA for the treatment of onchocerciasis in persons at least 12 years of age. MOX has been shown to have a good safety profile in recent clinical trials.
Y. Chhonker, Catherine M Bjerum, V. Bala, A. Ouattara, B. Koudou, T. P. Gabo, Abdullah S. Alshehri, Abdoulaye Meïté, Peter U. Fischer, G. Weil, C. King, Philip J. Budge, D. Murry   +12 more
semanticscholar   +1 more source

Moxidectin: heartworm disease prevention in dogs in the face of emerging macrocyclic lactone resistance

Parasites & Vectors, 2022
Heartworm ( Dirofilaria immitis ) disease continues to increase and spread, remaining one of the most important and pathogenic parasitic diseases of dogs, despite the regular use of macrocyclic lactones (MLs) in preventive products.
Molly D. Savadelis, T. McTier, Kristina Kryda, S. Maeder, D. Woods   +4 more
semanticscholar   +2 more sources

Strongyle egg reappearance periods following moxidectin treatment in horses in Southeast England

Equine Veterinary Education, 2023
Background: A reduction in the Egg Reappearance Period (ERP) has been suggested to be an early indication of emerging anthelmintic resistance in strongyles.
T. Mair, R. Opie, M. Moreton-Clack, T. Parkin, J. Matthews   +4 more
semanticscholar   +1 more source

Efficacy of imidacloprid + moxidectin and selamectin topical solutions against the KS1 Ctenocephalides felis flea strain infesting cats

Parasites & Vectors, 2011
Background Two studies were conducted to evaluate and compare the efficacy of imidacloprid + moxidectin and selamectin topical solutions against the KS1 flea strain infesting cats.
Dryden Michael W, Payne Patricia A, Smith Vicki, Hostetler Joe   +3 more
doaj   +1 more source

Pharmacoeconomic Analysis of Heartworm Preventive Compliance and Revenue in Veterinary Practices in the United States

Frontiers in Veterinary Science, 2021
Background: Heartworm disease (HWD) is a potentially fatal condition caused by the nematode Dirofilaria immitis. It is endemic in North America, and the American Heartworm Society recommends that owned dogs be on a Food and Drug Administration-approved ...
Kennedy Mwacalimba, Deborah Amodie, Lisa Swisher, Marina Moldavchuk, Christopher Brennan, Claire Walther, Kelly Bowman   +6 more
doaj   +1 more source

Effects of Oral Macrocyclic Lactone Heartworm Preventatives on Retinal Function and Chromatic Pupillary Light Reflex in Healthy Companion Dogs. [PDF]

Vet Ophthalmol
ABSTRACT Objective Determine the effect of oral macrocyclic lactone heartworm‐preventative medications on retinal function and chromatic pupillary light reflex (cPLR) in healthy dogs. Animals Studied Cross‐sectional retrospective: 60 dogs (n = 33 females) with heartworm medication administration status and electroretinogram (ERG) data available ...
Hopper RG, Ludwig AL, Salzman MM, Elazegui E, Rogers CM, Bentley E, Mowat FM.   +6 more
europepmc   +2 more sources

Efficacy of oral moxidectin against susceptible and resistant isolates of Dirofilaria immitis in dogs

Parasites & Vectors, 2017
Background Monthly topical and sustained-release injectable formulations of moxidectin are currently marketed; however, an oral formulation, while approved at a dose of 3 μg/kg, is not currently marketed in the United States.
Tom L. McTier, Robert H. Six, Aleah Pullins, Sara Chapin, John W. McCall, Douglas Rugg, Steven J. Maeder, Debra J. Woods   +7 more
doaj   +1 more source

Diagnosis and Treatment of Infectious Enteritis in Adult Ruminants. [PDF]

, 2018
Infectious enteritis in adult ruminants is often a result of 1 or more viral, bacterial, or parasitic pathogens. Diagnosis of etiologic agents causing enteritis is important when considering herd implications and zoonotic potential of some etiologies ...
Chigerwe, Munashe, Heller, Meera C
core   +1 more source