Results 141 to 150 of about 4,135 (173)

A simplified antigen-based serological algorithm accurately classifies MPXV exposure and vaccination status

open access: yes
Abdullahi A   +6 more
europepmc   +1 more source

GenomeBits Characterization of MPXV

open access: yesGenes, 2022
Genome sequences of monkeypox virus (MPVX) causing the current outbreak are being reported from an increasing number of countries. We present a letter-to-numerical sequence study via GenomeBits signal mapping in order to characterize the evolution of the MPXV via simple statistical analysis. Histograms, empirical and theoretical cumulative distribution
Enrique Canessa
exaly   +3 more sources

MPXV Transmission at a Tattoo Parlor

New England Journal of Medicine, 2023
Mario Linares   +2 more
exaly   +3 more sources

Comparative Analysis of 2022 Outbreak MPXV and Previous Clade II MPXV

open access: yesJournal of Medical Virology
ABSTRACT The 2022–2024 outbreak of MPOX is an important worldwide public health issue that has triggered significant concerns in the scientific community. MPOX is caused by monkeypox virus (MPXV) belonging to the Poxviridae family.
Gustavo Palacios   +2 more
exaly   +6 more sources

Bispecific Antibodies Targeting MPXV A29 and B6 Demonstrate Efficacy Against MPXV Infection.

open access: yesJournal of Virology
ABSTRACT Recently, the monkeypox virus (MPXV) outbreak was once again declared by the World Health Organization as a global health emergency, and currently, there is no specific drug against MPXV.
Chenguang Shen, Yang Yang, Jiayin Chen
exaly   +3 more sources

Mpox, Caused by the MPXV of the Clade IIb Lineage, Goes Global

open access: yesTropical Medicine and Infectious Disease, 2023
Mpox is a great public health concern worldwide currently; thus, a global primary epidemiological analysis of mpox and a phylogenetic analysis of currently circulating MPXV strains based on open-source data is necessary. A total of 83,419 confirmed cases with 72 deaths were reported from 7 May to 23 December 2022, representing an ongoing increasing ...
Zhi-Guo Liu, Zhenjun Li, Liping Gao
exaly   +4 more sources

Clade-Specific MPXV PCR Assays

2023
Abstract In an evolving infectious disease outbreak, there are two priorities: rapid and accurate detection of the causative agent and characterization of its spread. The polymerase chain reaction (PCR) assay is an effective and portable diagnostic method that can quickly provide information associated with virulence,
Daniel Antonio Negrón   +10 more
openaire   +1 more source

Tecovirimat Is Active Against Various MPXV Strains, While Cidofovir, Brincidofovir, Trifluridine, and Gemcitabine Have No Detectable MPXV-Specific Antiviral Activity

open access: yesVirus Research
In treating patients with mpox, current treatment options are limited, with tecovirimat (TEC) being one of the few available. TEC has been approved by the European Medicines Agency (EMA) for treating patients with mpox and is in clinical use in Europe and Japan. However, following exposure to TEC, TEC-resistant variants such as A290V-containing variant
Yuki Takamatsu   +2 more
exaly   +3 more sources

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