Results 151 to 160 of about 5,325 (169)

GenomeBits Characterization of MPXV

Genes, 2022
Genome sequences of the monkeypox virus (MPXV) causing the current outbreak are being reported from an increasing number of countries. We present a letter-to-numerical sequence study via GenomeBits signal mapping in order to characterize the evolution of
Enrique A Canessa
exaly   +2 more sources

Three neutralizing mAbs induced by MPXV A29L protein recognizing different epitopes act synergistically against orthopoxvirus

Emerging Microbes and Infections, 2023
The worldwide outbreak of the monkeypox virus (MPXV) has become a “Public Health Emergency of International Concern” (PHEIC). Severe monkeypox virus infection can be fatal, however, effective therapeutic methods are yet to be developed.
Jiayin Chen, Yuhao Lin
exaly   +3 more sources

Comparative Analysis of 2022 Outbreak MPXV and Previous Clade II MPXV

Journal of Medical Virology
The 2022–2024 outbreak of MPOX is an important worldwide public health issue that has triggered significant concerns in the scientific community. MPOX is caused by monkeypox virus (MPXV) belonging to the Poxviridae family.
Gustavo Palacios, Maria Paz Sánchez-Seco, Maria Susana Guerra Garcia   +2 more
exaly   +2 more sources

Designing a Multi-Epitope Vaccine Against MPXV and HIV Based on an Immunoinformatic Approach

International Journal of Molecular Sciences
In the current global health environment, the spread of the monkeypox virus (MPXV) and the persistent threat of human immunodeficiency virus (HIV) have become critical public health challenges.
Weijin Huang, Siwen Wu
exaly   +2 more sources

Enhanced Immunogenicity and Affinity with A35R-Fc-Based Chimeric Protein Compared to MPXV A35R Protein

Viruses
The re-emergence of the mpox pandemic poses considerable challenges to human health and societal development. There is an urgent need for effective prevention and treatment strategies against the mpox virus (MPXV).
Qibin Liao
exaly   +2 more sources

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Development and validation of a nanoplate-based digital PCR assay for absolute MPXV quantification

Journal of Virological Methods, 2023
Fabrizio Maggi, Claudia Minosse, Giulia Matusali   +2 more
exaly  

Mpox, Caused by the MPXV of the Clade IIb Lineage, Goes Global

Tropical Medicine and Infectious Disease, 2023
Zhiguo Liu, Zhenjun Li, Li-Ping Gao
exaly  

Monkeypox virus (MPXV) genomics: A mutational and phylogenomic analyses of B.1 lineages

Travel Medicine and Infectious Disease, 2023
Juan David Ramirez, Marina Munoz, D Katterine Bonilla-Aldana   +2 more
exaly  

Tecovirimat is active against various MPXV strains, while cidofovir, brincidofovir, trifluridine, and gemcitabine have no detectable MPXV-specific antiviral activity

Virus Research
Yuki Takamatsu, Hiroaki Mitsuya, Shin-Ichiro Hattori   +2 more
exaly  

Bispecific antibodies targeting MPXV A29 and B6 demonstrate efficacy against MPXV infection

Journal of Virology
Chenguang Shen, Jiayin Chen
exaly