Results 1 to 10 of about 88,502 (304)

MRL and SuperFine+MRL: new supertree methods [PDF]

open access: yesAlgorithms for Molecular Biology, 2012
Abstract Background Supertree methods combine trees on subsets of the full taxon set together to produce a tree on the entire set of taxa. Of the many supertree methods, the most popular is MRP (Matrix Representation with Parsimony), a method that operates by first encoding the input set of source trees by a large ...
Nguyen, Nam   +2 more
semanticscholar   +7 more sources

Japan MRL Regulation [PDF]

open access: yesAgricultural Economic Report Series, 2008
MRL, apple, cherry, export, Farm Management, International relations/trade, crop production/industries,
Takagi, Chifumi, Thornsbury, Suzanne
core   +4 more sources

The superior healing capacity of MRL tendons is minimally influenced by the systemic environment of the MRL mouse

open access: yesScientific Reports, 2023
AbstractMurphy Roths Large mice (MRL) exhibit improved tendon healing and are often described as a “super-healer” strain. The underlying mechanisms that drive the superior healing response of MRL remain a controversial subject. We utilized a tendon transplantation model between MRL and “normal-healer” B6-mice to differentiate between the contribution ...
Borys Frankewycz   +3 more
openaire   +3 more sources

Aberrant Gut Microbiome Contributes to Intestinal Oxidative Stress, Barrier Dysfunction, Inflammation and Systemic Autoimmune Responses in MRL/lpr Mice

open access: yesFrontiers in Immunology, 2021
Microbiome composition and function have been implicated as contributing factors in the pathogenesis of autoimmune diseases (ADs), including systemic lupus erythematosus (SLE), rheumatoid arthritis and autoimmune hepatitis (AIH).
Hui Wang   +7 more
semanticscholar   +1 more source

Gut microbiota mediated the therapeutic efficacies and the side effects of prednisone in the treatment of MRL/lpr mice

open access: yesArthritis Research & Therapy, 2021
Background Growing evidences indicate that the alterations in gut microbiota are associated with the efficacy of glucocorticoids (GCs) in the treatment of systemic lupus erythematosus (SLE).
Mingzhu Wang   +6 more
semanticscholar   +1 more source

Sjögren's syndrome in MRL/l and MRL/n mice [PDF]

open access: yesArthritis & Rheumatism, 1984
AbstractSix autoimmune murine models (MRL/l, MRL/n, NZB, NZB/NZW, PN, C57BL/6J‐lpr/lpr) were compared with normal control C57BL/6J and DBA/2 mice to determine if spontaneous autoimmune disease was associated with evidence of Sjögren's syndrome. Schirmer tests documented dry eyes in NZB/NZW and PN mice; other autoimmune strains and controls had normal ...
Margaret A. Alspaugh   +4 more
openaire   +3 more sources

Band Keratopathy in MRL/1 and MRL/n Mice [PDF]

open access: yesArthritis & Rheumatism, 1983
AbstractTo define ocular abnormalities in mice with autoimmune disease, we performed biomicroscopic examinations and examined ocular tissue in MRL/1, MRL/n, NZB, NZB/NZW, and Palmerston North mice. Results were compared with MRL/Mp‐Ipr/lpr, C57BL/6J‐lpr/lpr, and normal control strains.
Hoffman, R W   +5 more
openaire   +2 more sources

Intra-articular delivery of extracellular vesicles secreted by chondrogenic progenitor cells from MRL/MpJ superhealer mice enhances articular cartilage repair in a mouse injury model

open access: yesStem cell research & therapeutics, 2020
Chondrogenic progenitor cells (CPCs) have high self-renewal capacity and chondrogenic potential. Intra-articular delivery of purified mesenchymal stem cells (MSCs) from MRL/MpJ “superhealer” mice increased bone volume during repair and prevents post ...
Rikang Wang   +7 more
semanticscholar   +1 more source

Jieduquyuziyin Prescription Suppresses Inflammatory Activity of MRL/lpr Mice and Their Bone Marrow-Derived Macrophages via Inhibiting Expression of IRAK1-NF-κB Signaling Pathway

open access: yesFrontiers in Pharmacology, 2020
Jieduquyuziyin prescription (JP) has been used to treat systemic lupus erythematosus (SLE). Although the effectiveness of JP in the treatment of SLE has been clinically proven, the underlying mechanisms have yet to be completely understood.
Lina Ji   +8 more
semanticscholar   +1 more source

The scarless heart and the MRL mouse [PDF]

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2004
The ability to regenerate tissues and limbs in its most robust form is seen in many non–mammalian species. The serendipitous discovery that the MRL mouse has a profound capacity for regeneration in some ways rivalling the classic newt and axolotl species raises the possibility that humans, too, may have an innate regenerative ability.
Lise Clark   +4 more
openaire   +3 more sources

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