Alterations of mRNA and lncRNA profiles associated with the extracellular matrix and spermatogenesis in goats [PDF]
Animal Bioscience, 2022 Objective Spermatozoa are produced within the seminiferous tubules after sexual maturity. The expression levels of mRNAs and lncRNAs in testicular tissues are different at each stage of testicular development and are closely related to formation of the ...
Haolin Chen +7 more
doaj +1 more source
Additional diagnostic capabilities in the practice of a PAP-test using liquid-based cytology [PDF]
Клиническая практика, 2021 The role of oncogenic strains of human papillomavirus in the development of cervical cancer is currently not in doubt. In cervical cancer screening, a co-testing strategy is used, in which cytology and HPV testing are performed.
Artem K. Aksamentov +4 more
doaj +1 more source
Snca and Bdnf gene expression in the VTA and raphe nuclei of midbrain in chronically victorious and defeated male mice [PDF]
, 2010 The study aimed to analyze the mRNA levels of Snca and Bdnf genes in the ventral tegmental area (VTA) and raphe nuclei of the midbrain in male mice that had each won or defeated 20 encounters in daily agonistic interactions.
Mark R. Cookson +4 more
core +11 more sources
Relationship between HER2 expression and efficacy with first-line trastuzumab emtansine compared with trastuzumab plus docetaxel in TDM4450g: a randomized phase II study of patients with previously untreated HER2-positive metastatic breast cancer. [PDF]
, 2014 IntroductionThe purpose of this study was to retrospectively explore the relationship between human epidermal growth factor receptor 2 (HER2) messenger RNA (mRNA) expression and efficacy in patients receiving trastuzumab plus docetaxel (HT) or ...
Amler, Lukas C +6 more
core +10 more sources
Евразийский Кардиологический Журнал, 2023 Cardiovascular diseases are one of the most common causes of death in both developing and developed countries of the world. Despite the improvement in primary prevention, the prevalence of cardiovascular diseases has continued to grow in recent years.
O. Iu. Mironova +3 more
doaj +1 more source
An agent-based model for mRNA export through the nuclear pore complex. [PDF]
, 2014 mRNA export from the nucleus is an essential step in the expression of every protein- coding gene in eukaryotes, but many aspects of this process remain poorly understood.
Azimi, Mohammad +3 more
core +2 more sources
Increased expression of aggrecan and biglycan mRNA in Achilles tendinopathy [PDF]
, 2006 To determine the expression of mRNA encoding the proteoglycans aggrecan, versican, biglycan and decorin in mid-tendon samples of chronic painful Achilles tendinopathy and ruptured Achilles tendons, compared with normal tendons.
Corps, AN +5 more
core +1 more source
Identification of potential genes associated with immune cell infiltration in atherosclerosis
Mathematical Biosciences and Engineering, 2021 Background: This study aimed to analyze the potential genes associated with immune cell infiltration in atherosclerosis (AS). Methods: Gene expression profile data (GSE57691) of human arterial tissue samples were downloaded, and differentially ...
Xiaodong Xia +6 more
doaj +1 more source
Inference of RNA decay rate from transcriptional profiling highlights the regulatory programs of Alzheimer's disease. [PDF]
, 2017 The abundance of mRNA is mainly determined by the rates of RNA transcription and decay. Here, we present a method for unbiased estimation of differential mRNA decay rate from RNA-sequencing data by modeling the kinetics of mRNA metabolism.
Alkallas, Rached +3 more
core +3 more sources
Inhibition of translation by poliovirus: Inactivation of a specific initiation factor [PDF]
, 1978 Translation of vesicular stomatitis virus (VSV) mRNA, like host mRNA translation, is inhibited in cells infected with poliovirus. To study the mechanism of poliovirus-induced inhibition of protein synthesis, we prepared extracts from poliovirus-infected ...
Baltimore, David +3 more
core +1 more source