Results 181 to 190 of about 2,706,783 (351)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Differences in Yes-associated protein and mRNA levels in regenerating liver and hepatocellular carcinoma

, 2011
Jiahong Dong
openalex   +2 more sources

Amphotericin B severely affects expression and activity of the endothelial constitutive nitric oxide synthase involving altered mRNA stability [PDF]

, 2000
Christoph V. Suschek, Eckhard Bonmann, Hartmut Kleinert, Michael Wenzel, Csaba Mahotka, Hubert Kolb, Ulrich Förstermann, Claus‐Dieter Gerharz, Victoria Kolb‐Bachofen   +8 more
openalex   +1 more source

Effect of Dietary Supplementation with Dried Tuber of Jerusalem Artichoke on Skatole Level in Backfat and CYP2E1 mRNA Expression in Liver of Boars [PDF]

, 2020
Kateřina Zadinová, A. Stratil, Mario Van Poucke, Luc Peelman, Jaroslav Čítek, Monika Okrouhlá, Nicole Lebedová, Kamila Pokorná, M. Šprysl, Roman Stupka   +9 more
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

The mRNA-Based Innovative Strategy: Progress and Challenges. [PDF]

Nanomicro Lett
Zhou H, Wei D, Chen Z, Chen H, Dong C, Yao W, Wang J, Liu X, Li Y, Yang Y, Tan W.   +10 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Freeze-Drying in Sucrose Followed by Cryomilling Enables the Formulation of sa-mRNA-LNP Powders for Inhalation. [PDF]

Pharmaceutics
Jansen EM, Ruigrok MJR, Suh MS, Ruppel PM, Cui X, Opsomer L, Sanders NN, Frijlink HW, Hinrichs WLJ.   +8 more
europepmc   +1 more source

An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK-APRIL fusion protein

, 2002
Bérengère Pradet‐Balade
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source