Results 11 to 20 of about 2,344,135 (339)
Identification of potential genes associated with immune cell infiltration in atherosclerosis
Mathematical Biosciences and Engineering, 2021 Background: This study aimed to analyze the potential genes associated with immune cell infiltration in atherosclerosis (AS). Methods: Gene expression profile data (GSE57691) of human arterial tissue samples were downloaded, and differentially ...
Xiaodong Xia +6 more
doaj +1 more source
Emerging Microbes and Infections, 2022 Host circular RNAs (circRNAs) play critical roles in the pathogenesis of viral infections. However, how viruses modulate the biogenesis of host proviral circRNAs to facilitate their replication remains unclear.
Xi Zhang +13 more
doaj +1 more source
Polyester materials for mRNA delivery
Exploration of Targeted Anti-tumor Therapy, 2022 Messenger RNA (mRNA) has recently made important progress in clinical implementation, offering a promising therapeutic option for infectious disease and cancer. However, the nature of mRNA molecules rendered them poorly bioavailable and unstable in vivo,
Wang Chen +3 more
doaj +1 more source
Sensitivity of mRNA Translation [PDF]
Scientific Reports, 2015 AbstractUsing the dynamic mean-field approximation of the totally asymmetric simple exclusion process (TASEP), we investigate the effect of small changes in the initiation, elongation and termination rates along the mRNA strand on the steady-state protein translation rate.
Gilad Poker +2 more
openaire +4 more sources
Conditioned spin and charge dynamics of a single electron quantum dot [PDF]
, 2017 In this article we describe the incoherent and coherent spin and charge dynamics of a single electron quantum dot. We use a stochastic master equation to model the state of the system, as inferred by an observer with access to only the measurement signal.
Ariane Beauvais (221768) +15 more
core +9 more sources
Additional diagnostic capabilities in the practice of a PAP-test using liquid-based cytology [PDF]
Клиническая практика, 2021 The role of oncogenic strains of human papillomavirus in the development of cervical cancer is currently not in doubt. In cervical cancer screening, a co-testing strategy is used, in which cytology and HPV testing are performed.
Artem K. Aksamentov +4 more
doaj +1 more source
Industrial Psychiatry Journal, 2021 “Necessity is the mother of invention:” An adage was brought to life with the emergence of the mRNA vaccine against the backdrop of the foreboding and mercurial COVID-19 pandemic. Considering a negligible adverse-effect profile and a break-neck manufacturing speed, it shone bright as the ideal vaccine candidate.
AV Sowmya +4 more
openaire +4 more sources
Increased expression of aggrecan and biglycan mRNA in Achilles tendinopathy [PDF]
, 2006 To determine the expression of mRNA encoding the proteoglycans aggrecan, versican, biglycan and decorin in mid-tendon samples of chronic painful Achilles tendinopathy and ruptured Achilles tendons, compared with normal tendons.
Corps, AN +5 more
core +1 more source
Quantifying mRNA synthesis and decay rates using small RNAs [PDF]
, 2009 Regulation of mRNA decay is a critical component of global cellular adaptation to changing environments. The corresponding changes in mRNA lifetimes can be coordinated with changes in mRNA transcription rates to fine-tune gene expression.
Bernstein +21 more
core +3 more sources
FEBS Letters, 2001 Export of mRNA through nuclear pore complexes (NPC) is preceded by multiple and well coordinated processing steps, resulting in the formation of an export competent ribonucleoprotein complex (mRNP). Numerous factors involved in the translocation of the mRNP through the NPC and its release into the cytoplasm have been isolated mainly through genetic ...
Zenklusen, D, Stutz, Françoise
openaire +4 more sources