Quantifying mRNA synthesis and decay rates using small RNAs [PDF]
, 2009 Regulation of mRNA decay is a critical component of global cellular adaptation to changing environments. The corresponding changes in mRNA lifetimes can be coordinated with changes in mRNA transcription rates to fine-tune gene expression.
Bernstein +21 more
core +4 more sources
Alterations of mRNA and lncRNA profiles associated with the extracellular matrix and spermatogenesis in goats [PDF]
Animal Bioscience, 2022 Objective Spermatozoa are produced within the seminiferous tubules after sexual maturity. The expression levels of mRNAs and lncRNAs in testicular tissues are different at each stage of testicular development and are closely related to formation of the ...
Haolin Chen +7 more
doaj +1 more source
Integrative Analysis Of LncRNAs In Kidney Cancer To Discover A New LncRNA (LINC00847) As A Therapeutic Target For Staphylococcal Enterotoxin Tst Gene [PDF]
Cell Journal, 2020 Objective Bacterial toxin can cause cell death through induction of apoptosis in cancer cell lines as well as changes in the expression patterns of long non-coding RNAs (lncRNAs) and genes. In the present study, the effect of tst gene on ACHN cell lines
Maryam Safarpour-Dehkordi +2 more
doaj +1 more source
Identification of potential genes associated with immune cell infiltration in atherosclerosis
Mathematical Biosciences and Engineering, 2021 Background: This study aimed to analyze the potential genes associated with immune cell infiltration in atherosclerosis (AS). Methods: Gene expression profile data (GSE57691) of human arterial tissue samples were downloaded, and differentially ...
Xiaodong Xia +6 more
doaj +1 more source
Emerging Microbes and Infections, 2022 Host circular RNAs (circRNAs) play critical roles in the pathogenesis of viral infections. However, how viruses modulate the biogenesis of host proviral circRNAs to facilitate their replication remains unclear.
Xi Zhang +13 more
doaj +1 more source
Polyester materials for mRNA delivery
Exploration of Targeted Anti-tumor Therapy, 2022 Messenger RNA (mRNA) has recently made important progress in clinical implementation, offering a promising therapeutic option for infectious disease and cancer. However, the nature of mRNA molecules rendered them poorly bioavailable and unstable in vivo,
Wang Chen +3 more
doaj +1 more source
Conditioned spin and charge dynamics of a single electron quantum dot [PDF]
, 2017 In this article we describe the incoherent and coherent spin and charge dynamics of a single electron quantum dot. We use a stochastic master equation to model the state of the system, as inferred by an observer with access to only the measurement signal.
Ariane Beauvais (221768) +15 more
core +9 more sources
Additional diagnostic capabilities in the practice of a PAP-test using liquid-based cytology [PDF]
Клиническая практика, 2021 The role of oncogenic strains of human papillomavirus in the development of cervical cancer is currently not in doubt. In cervical cancer screening, a co-testing strategy is used, in which cytology and HPV testing are performed.
Artem K. Aksamentov +4 more
doaj +1 more source
Increased expression of aggrecan and biglycan mRNA in Achilles tendinopathy [PDF]
, 2006 To determine the expression of mRNA encoding the proteoglycans aggrecan, versican, biglycan and decorin in mid-tendon samples of chronic painful Achilles tendinopathy and ruptured Achilles tendons, compared with normal tendons.
Corps, AN +5 more
core +1 more source
An agent-based model for mRNA export through the nuclear pore complex. [PDF]
, 2014 mRNA export from the nucleus is an essential step in the expression of every protein- coding gene in eukaryotes, but many aspects of this process remain poorly understood.
Azimi, Mohammad +3 more
core +2 more sources