Results 31 to 40 of about 2,344,135 (339)
Increased Litter Size and Suckling Intensity Stimulate mRNA of RFamide-related Peptide in Rats [PDF]
Background RFamide-related peptide-3 (RFRP-3) inhibits gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in rats. This study evaluates the effects of litter size and suckling intensity on RFRP mRNA expression in the dorsomedial
Atefeh Noroozi+4 more
doaj +1 more source
Microarray profile of B cells from Graves’ disease patients reveals biomarkers of proliferation
B lymphocytes are the source of autoantibodies against the thyroid-stimulating hormone receptor (TSHR) in Graves’ disease (GD). Characterization of au toimmune B-cell expression profiles might enable a better understanding of GD pathogenesis.
Xuechao Jiang+7 more
doaj +1 more source
The onset of labor alters corticotropin-releasing hormone type 1 receptor variant expression in human myometrium : putative role of interleukin-1ß [PDF]
CRH targets the human myometrium during pregnancy. The efficiency of CRH actions is determined by expression of functional receptors (CRH-R), which are dynamically regulated.
Grammatopoulos, Dimitris+6 more
core +1 more source
mRNA (messenger RNA) is a large class of single-stranded RNA molecules, and a blueprint for protein synthesis, transferring the genetic information from the DNA to the ribosome, where they specify the amino acid sequence of the protein product. During the movement of the ribosome along the mRNA, the base sequence on the mRNA is read and each three-base
openaire +2 more sources
Erratum: Corrigendum: mRNA–mRNA duplexes that autoelicit Staufen1-mediated mRNA decay [PDF]
Nat. Struct. Mol. Biol. 20, 1214–1220 (2013); published online 22 September 2013; corrected after print 4 December 2013 In the version of this article initially published, the last sentence of the Figure 5 legend reads: “Downregulation of SOWAHC mRNA inhibits SOWAHC mRNA-CDCP1 mRNA base-pairing and thus the SOWAHC mRNA-mediated SMD of CDCP1 mRNA, an ...
Chenguang Gong+2 more
openaire +2 more sources
mRNA, a Revolution in Biomedicine [PDF]
The perspective of using messenger RNA (mRNA) as a therapeutic molecule first faced some uncertainties due to concerns about its instability and the feasibility of large-scale production. Today, given technological advances and deeper biomolecular knowledge, these issues have started to be addressed and some strategies are being exploited to overcome ...
Bruno Baptista+4 more
openaire +3 more sources
Tissue Cytokine Responses in Canine Visceral Leishmaniasis [PDF]
To elucidate the local tissue cytokine response of dogs infected with Leishmania chagasi, cytokine mRNA levels were measured in bone marrow aspirates from 27 naturally infected dogs from Brazil and were compared with those from 5 uninfected control ...
Courtenay, O.+6 more
core +2 more sources
Background: Smoking is considered the single highest risk factor for lung cancer and has been suggested to be associated with accelerated somatic mutations in respiratory mucosa that lead to the development of lung cancer.
Amresh Kumar Mishra+2 more
doaj +1 more source
Introduction: Asthma being a chronic inflammatory disease concerning to the airways involves genetic and environmental factors. It is known to develop a clinical condition of airway hyper-responsiveness, which induces frequent symptoms in patients such ...
Rashmi Pandey, Ved Prakash
doaj +1 more source
A myelopoiesis gene signature in circulating leucocytes, exemplified by increased myeloperoxidase (MPO) and proteinase 3 (PR3) mRNA levels, has been reported in patients with active anti-neutrophil cytoplasm antibody associated vasculitis (AAV) and to a ...
Basnet, Sandeep+5 more
core +2 more sources