Results 41 to 50 of about 2,522,941 (181)
Promising leads against lung cancer from the plants in Lamiaceae family [PDF]
BioImpactsIntroduction: Ceaselessly, management of cancer has been the major global challenge for healthcare professionals. As regards, lung cancer (LC) has been introduced as the second most common form of cancer in both men and women, taking the lives of more ...
Alireza Rahimlouy Aghdam +1 more
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Cells, 2020 The oocyte faces a particular challenge in terms of gene regulation. When oocytes resume meiosis at the end of the growth phase and prior to ovulation, the condensed chromatin state prevents the transcription of genes as they are required.
Marie Christou-Kent +4 more
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All Life, 2023 Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus. Recent studies have explored the involvement of long non-coding RNA (lncRNA) in diabetes, but its specific role in DPN development remains unclear.
Dongdong Yu +6 more
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A snoRNA modulates mRNA 3' end processing and regulates the expression of a subset of mRNAs. [PDF]
, 2017 mRNA 3' end processing is an essential step in gene expression. It is well established that canonical eukaryotic pre-mRNA 3' processing is carried out within a macromolecular machinery consisting of dozens of trans-acting proteins. However, it is unknown
Ding, Junjun +14 more
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Frontiers in Cell and Developmental BiologyPersistent infection with high-risk human papillomaviruses (HR-HPVs) is a major etiological factor in the development of cervical cancer, which ranks as the fourth leading cause of cancer-related mortality among women worldwide.
Noemi Baranda-Ávila +4 more
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CHEMOKINES AND THEIR RECEPTORS EXPRESSION IN BLOOD AND LIVER TISSUE IN CHRONIC HEPATITIS C
Медицинская иммунология, 2014 . Chronic hepatitis C (CHC) is widely spread disease with a long incubation period and weakle expressed clinical features. Pathogenesis of CHC despite of intensive efforts is still unclear.
K. V. Zhdanov +6 more
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Peptide-enhanced mRNA transfection in cultured mouse cardiac fibroblasts and direct reprogramming towards cardiomyocyte-like cells. [PDF]
, 2015 The treatment of myocardial infarction is a major challenge in medicine due to the inability of heart tissue to regenerate. Direct reprogramming of endogenous cardiac fibroblasts into functional cardiomyocytes via the delivery of transcription factor ...
Kim, Hyun Jin +5 more
core +3 more sources
Биопрепараты: Профилактика, диагностика, лечение, 2019 This review focuses on DNA and RNA vaccines whose potential use was first considered at the end of the 20th century. However, not a single bacterial plasmid-based or mRNA vaccine has been used since that time in public healthcare for the prevention of ...
A. A. Goryaev +4 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2017 Eukaryotic mRNA with its 5′-cap is of central importance for the cell. Many studies involving mRNA require reliable preparation and modification of 5′-capped RNAs. Depending on the length of the desired capped RNA, chemical or enzymatic preparation – or a combination of both – can be advantageous.
Fabian Muttach +2 more
openaire +3 more sources
Expression of the Thyroid Hormone Receptor Gene, erbAα, in B Lymphocytes: Alternative mRNA Processing is Independent of Differentiation but Correlates with Antisense RNA Levels [PDF]
, 1997 The erbAα gene encodes two α-thyroid hormone receptor isoforms, TRα1 and TRα2, which arise from alternatively processed mRNAs, erbAα1 (α1) and erb α2 (α2).
Hastings, Michelle Laura +4 more
core +1 more source