Results 61 to 70 of about 1,902,766 (313)
Selection of suitable reference genes for real-time PCR studies of early developmental stages of sturgeons [PDF]
بومشناسی آبزیان, 2013 In quantitative real-time PCR, the mRNA level can be quantified in relative terms based on the expression ratio of mRNAs of the target gene and an internal reference gene.
Arash Akbarzadeh +5 more
doaj
Czech Journal of Animal Science, 2008 Skeletal muscle growth is determined by the number of prenatally formed fibres and by the degree of their postnatal hypertrophy; i.e. prenatal development may influence the postnatal growth.
K. Bílek +7 more
doaj +1 more source
Increased Litter Size and Suckling Intensity Stimulate mRNA of RFamide-related Peptide in Rats [PDF]
International Journal of Fertility and Sterility, 2015 Background RFamide-related peptide-3 (RFRP-3) inhibits gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in rats. This study evaluates the effects of litter size and suckling intensity on RFRP mRNA expression in the dorsomedial
Atefeh Noroozi +4 more
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
On the role of ras and BRF1 in the regulation of ARE-dependent mRNA-turnover [PDF]
, 2004 Stability of the mRNAs of cytokines, chemokines, growth-factors, protooncogenes and others are regulated via an AU-rich element (ARE) in their 3’ untranslated region (UTR).
Leuenberger, Sabrina Angélique
core +1 more source
Small StructuresmRNA‐loaded lipid nanoparticles (LNPs) offer significant therapeutic potential for various diseases, yet their structural characteristics and component distribution remain incompletely understood. This study utilizes small‐angle neutron scattering (SANS)
Haikun Liu +12 more
doaj +1 more source
AUGcontext DB: a comprehensive catalog of the mRNA AUG initiator codon context across eukaryotes
RNA BiologyThe mRNA translation defines the composition of the cell proteome in all forms of life and diseases. In this process, precise selection of the mRNA translation initiation site (TIS) is crucial, as it establishes the correct open reading frame for triplet
Vincent G. Osnaya +3 more
doaj +1 more source
Genome-wide mRNA surveillance is coupled to mRNA export [PDF]
Genes & Development, 2004 Nuclear export of mRNA is a central step in gene expression that shows extensive coupling to transcription and transcript processing. However, little is known about the fate of mRNA and its export under conditions that damage the DNA template and RNA itself.
Haley, Hieronymus +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
SRAG Functions as a New mRNA Export Co-adaptor [PDF]
, 2012 DEAD box RNA helicases play important roles in many cellular processes including splicing, mRNA export and translation. The two domains of many DEAD box RNA helicases adopt radically different conformations according to whether they are ...
Chang, Chung-Te
core