Results 61 to 70 of about 2,541,766 (304)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Small StructuresmRNA‐loaded lipid nanoparticles (LNPs) offer significant therapeutic potential for various diseases, yet their structural characteristics and component distribution remain incompletely understood. This study utilizes small‐angle neutron scattering (SANS)
Haikun Liu +12 more
doaj +1 more source
Cost-effectiveness analysis of COVID-19 booster vaccination with BNT162b2 in Japan
Expert Review of VaccinesBackground The aim of this study was to evaluate the public health and economic impact of the COVID-19 booster vaccination with BNT162b2 in Japan during an Omicron-dominant period from early 2022.Research design and methods A combined cohort Markov ...
Mitsuhiro Nagano +6 more
doaj +1 more source
Selection of suitable reference genes for real-time PCR studies of early developmental stages of sturgeons [PDF]
بومشناسی آبزیان, 2013 In quantitative real-time PCR, the mRNA level can be quantified in relative terms based on the expression ratio of mRNAs of the target gene and an internal reference gene.
Arash Akbarzadeh +5 more
doaj
Czech Journal of Animal Science, 2008 Skeletal muscle growth is determined by the number of prenatally formed fibres and by the degree of their postnatal hypertrophy; i.e. prenatal development may influence the postnatal growth.
K. Bílek +7 more
doaj +1 more source
Increased Litter Size and Suckling Intensity Stimulate mRNA of RFamide-related Peptide in Rats [PDF]
International Journal of Fertility and Sterility, 2015 Background RFamide-related peptide-3 (RFRP-3) inhibits gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in rats. This study evaluates the effects of litter size and suckling intensity on RFRP mRNA expression in the dorsomedial
Atefeh Noroozi +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
AUGcontext DB: a comprehensive catalog of the mRNA AUG initiator codon context across eukaryotes
RNA BiologyThe mRNA translation defines the composition of the cell proteome in all forms of life and diseases. In this process, precise selection of the mRNA translation initiation site (TIS) is crucial, as it establishes the correct open reading frame for triplet
Vincent G. Osnaya +3 more
doaj +1 more source
Expression of plasma prekallikrein mRNA in human nonhepatic tissues and cell lineages suggests special local functions of the enzyme [PDF]
, 1999 At present it is generally accepted that plasma prekallikrein (PPK) is synthesized in the liver and secreted into the bloodstream. Surprisingly, it has recently been shown that PPK mRNA is present also in RNA from the kidney, adrenal gland and placenta ...
Arnhold, Marianne +4 more
core +1 more source
, 2023 mRNA (messenger RNA) is a large class of single-stranded RNA molecules, and a blueprint for protein synthesis, transferring the genetic information from the DNA to the ribosome, where they specify the amino acid sequence of the protein product. During the movement of the ribosome along the mRNA, the base sequence on the mRNA is read and each three-base
openaire +2 more sources