Results 71 to 80 of about 2,084,278 (307)

Structural characterization of

Materials & Design
The limited availability of effective adjuvants for mRNA vaccines necessitates the exploration of novel immunostimulatory agents. Here, we isolated and structurally characterized an acidic polysaccharide (LCAP) from the traditional Chinese herb ...
Chongyu Tian, Jiaojiao Nie, Yue Chen, Chao Dong, Mingshuo Ji, Yujing Liu, Jiaqi Nie, Xinhao Zhang, Jixiang Sun, Jiahan Gang, He Huang, Yongfei Zhou, Lin Jin, Wanbo Tai   +13 more
doaj   +1 more source

Selection of suitable reference genes for real-time PCR studies of early developmental stages of sturgeons [PDF]

بوم‌شناسی آبزیان, 2013
In quantitative real-time PCR, the mRNA level can be quantified in relative terms based on the expression ratio of mRNAs of the target gene and an internal reference gene.
Arash Akbarzadeh, Hamid Farahmand, Frouzandeh Mahjoubi, Mohammad Ali Nematollahi, Kamahldin Haghbeen, Hamed Kolangi Miandareh   +5 more
doaj  

Expression of Tau Protein and Tau mRNA in gastric carcinoma

Asian Journal of Medical Sciences, 2015
Aims and Objectives: To provide theoretical basis for the gastric carcinoma pathogenesis and the clinical targeted therapy. Materials and Methods: We detected the expression of Tau protein and Tau mRNA in 60 cases of gastric carcinoma tissues ...
Chun-hui Li
doaj   +1 more source

Sorting live stem cells based on Sox2 mRNA expression. [PDF]

, 2012
PMCID: PMC3507951This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited ...
Hans M. Larsson (118208), Frey Peter, Larsson, H.M., Velluto, Diana, Hans M. Larsson, Jeffrey A. Hubbell (118232), Roccio Marta, Velluto Diana, Lee, S.T., Hubbell, Jeffrey A., Jeffrey A. Hubbell, Roccio, Marta, Peter Frey (118226), Lee, ST, Roccio, M, Matthias P Lutolf, Lutolf, MP, Velluto, D., Larsson, Hans M., Matthias P. Lutolf (118222), Lutolf, M.P., Frey, P., Larsson Hans M., Jeffrey A Hubbell, Seung Tae Lee, Lutolf Matthias P., Marta Roccio, Hubbell Jeffrey A., Larsson, HM, Velluto, D, Diana Velluto (118218), Peter Frey, Matthias P. Lutolf, Hubbell, JA, Lutolf, Matthias P., Hubbell, J.A., Lee Seung Tae, Roccio, M., Frey, Peter, Lee, Seung Tae, Marta Roccio (118214), Diana Velluto, Hans M Larsson, Seung Tae Lee (118211), Frey, P, Larsson HM, Frey P, Lutolf MP, Hubbell JA, Velluto D, Roccio M, Lee ST   +51 more
core   +3 more sources

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

AUGcontext DB: a comprehensive catalog of the mRNA AUG initiator codon context across eukaryotes

RNA Biology
The mRNA translation defines the composition of the cell proteome in all forms of life and diseases. In this process, precise selection of the mRNA translation initiation site (TIS) is crucial, as it establishes the correct open reading frame for triplet
Vincent G. Osnaya, Laura Gómez-Romero, Gabriel Moreno-Hagelsieb, Greco Hernández   +3 more
doaj   +1 more source

Tspan8-Tumor Extracellular Vesicle-Induced Endothelial Cell and Fibroblast Remodeling Relies on the Target Cell-Selective Response

Cells, 2020
Tumor cell-derived extracellular vesicles (TEX) expressing tetraspanin Tspan8-alpha4/beta1 support angiogenesis. Tspan8-alpha6/beta4 facilitates lung premetastatic niche establishment.
Wei Mu, Jan Provaznik, Thilo Hackert, Margot Zöller   +3 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Unlocking the Architecture and Component Distribution of Bioengineered and Derived Colloidal Structures from Blood with Neutron Scattering

Small Structures
Blood‐ and blood cell‐derived colloidal materials are gaining traction as platforms for targeted therapeutics, imaging, and theranostics. To fully exploit their potential, high‐resolution insight into their structural and compositional features is ...
Cuong Viet Pham, Haikun Liu, Joshua P. King, Shulei Ren, Sylvain Trépout, Alexis I. Bishop, Rico F. Tabor, Karlheinz Peter, Liliana de Campo, Mark Louis P. Vidallon, Xiaowei Wang   +10 more
doaj   +1 more source

Cost-effectiveness analysis of COVID-19 booster vaccination with BNT162b2 in Japan

Expert Review of Vaccines
Background The aim of this study was to evaluate the public health and economic impact of the COVID-19 booster vaccination with BNT162b2 in Japan during an Omicron-dominant period from early 2022.Research design and methods A combined cohort Markov ...
Mitsuhiro Nagano, Kazumasa Kamei, Hiroyuki Matsuda, Chihiro Takahashi, Jingyan Yang, Koji Wada, Naohiro Yonemoto   +6 more
doaj   +1 more source