A workflow to define structural classes and classify nucleic acids circular dichroism spectra
QRB DiscoveryCircular dichroism (CD) spectroscopy is a widely utilized technique for studying the structures of chiral molecules, including nucleic acids. It is particularly valued for its ability to quickly probe structural changes in these biomolecules. Despite its
Kevin Mosca +5 more
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EXPRESSION OF AID-SPECIFIC mRNA IN PERIPHERAL BLOOD LYMPHOCYTES IN BRONCHIAL ASTHMA
Медицинская иммунология, 2015 The aim of this study was to evaluate a possible role of AID (AICDA – activation-induced (cytidine) deaminase) in the bronchial asthma (BA) pathogenesis. Materials and methods.
V. N. Mineev +2 more
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Estradiol, Progesterone, and Transforming Growth Factor α Regulate Insulin-Like Growth Factor Binding Protein-3 (IGFBP3) Expression in Mouse Endometrial Cells [PDF]
, 2009 Insulin-like growth factor 1 (IGF1) Is Involved in the proliferation of mouse and rat endometrial cells in a paracrine or autocrine manner. Insulin-like growth factor binding protein-3 (IGFBP3) modulates actions of IGFs directly or indirectly.
Hembree JR +10 more
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Induction of WNT16 via peptide-mRNA nanoparticle-based delivery maintains cartilage homeostasis [PDF]
, 2020 Osteoarthritis (OA) is a progressive joint disease that causes significant disability and pain and for which there are limited treatment options. We posit that delivery of anabolic factors that protect and maintain cartilage homeostasis will halt or ...
Akk, Antonina +6 more
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Genomic structure and expression of the porcine ACTC1 gene
Czech Journal of Animal Science, 2018 A partial cDNA (~1200 bp) of the porcine ACTC1 gene was identified in the subtracted foetal hind limb muscle cDNA library (44 days of gestation; using m. biceps femoris cDNA as the driver).
Antonín Stratil +9 more
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Small StructuresmRNA‐loaded lipid nanoparticles (LNPs) offer significant therapeutic potential for various diseases, yet their structural characteristics and component distribution remain incompletely understood. This study utilizes small‐angle neutron scattering (SANS)
Haikun Liu +12 more
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Cost-effectiveness analysis of COVID-19 booster vaccination with BNT162b2 in Japan
Expert Review of VaccinesBackground The aim of this study was to evaluate the public health and economic impact of the COVID-19 booster vaccination with BNT162b2 in Japan during an Omicron-dominant period from early 2022.Research design and methods A combined cohort Markov ...
Mitsuhiro Nagano +6 more
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Selection of suitable reference genes for real-time PCR studies of early developmental stages of sturgeons [PDF]
بومشناسی آبزیان, 2013 In quantitative real-time PCR, the mRNA level can be quantified in relative terms based on the expression ratio of mRNAs of the target gene and an internal reference gene.
Arash Akbarzadeh +5 more
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Czech Journal of Animal Science, 2008 Skeletal muscle growth is determined by the number of prenatally formed fibres and by the degree of their postnatal hypertrophy; i.e. prenatal development may influence the postnatal growth.
K. Bílek +7 more
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Increased Litter Size and Suckling Intensity Stimulate mRNA of RFamide-related Peptide in Rats [PDF]
International Journal of Fertility and Sterility, 2015 Background RFamide-related peptide-3 (RFRP-3) inhibits gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in rats. This study evaluates the effects of litter size and suckling intensity on RFRP mRNA expression in the dorsomedial
Atefeh Noroozi +4 more
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