Results 81 to 90 of about 2,522,941 (181)
Science, 2016 DNA Events DNA is packaged into chromatin, and it must be actively unpacked, or remodeled, for genes to be transcribed into mRNA. That mRNA, synthesized in the nucleus, is also packed onto proteins, forming mRNA ribonucleoparticles (mRNPs). mRNPs are then shunted into the cytoplasm. Babour et al.
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A minimum principle in mRNA editing ?
, 2001 mRNA editing of sequences of many species is analyzed. The nature of the inserted nucleotides and the position of the insertion sites, once fixed the edited peptide chain, are explained by introducing a minimum principle in the framework of the crystal ...
Frappat, L., Sciarrino, A., Sorba, P.
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Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay. [PDF]
, 2015 Skeletal muscle satellite cells in their niche are quiescent and upon muscle injury, exit quiescence, proliferate to repair muscle tissue, and self-renew to replenish the satellite cell population.
Blackshear, Perry J +7 more
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An ensemble method to predict target genes and pathways in uveal melanoma
Open Life Sciences, 2018 This work proposes to predict target genes and pathways for uveal melanoma (UM) based on an ensemble method and pathway analyses. Methods: The ensemble method integrated a correlation method (Pearson correlation coefficient, PCC), a causal inference ...
Wei Chao, Wang Lei, Zhang Han
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Ontogenic Profile of Gluconeogenic Key Enzyme Gene Expressions in Embryonic Chicken Liver and Muscle
The Journal of Poultry Science, 2013 To elucidate biochemical mechanisms underlining high plasma glucose in chicken embryo, gene expression profile of gluconeogenic key enzymes were characterized.
Tushar K. Roy +4 more
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SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019 The present study describes the synthesis of a series of 22 chalcone analogs. These compounds were evaluated as potential human MAO-A and MAO-B inhibitors. The compounds showed varied selectivity against the two isoforms. The IC50 values were found to be
Raed Shalaby +8 more
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4 open, 2019 It is increasingly evident that carcinogenesis, in the vast majority of cancers, cannot be explained simply through an accumulation of somatic mutations, or epigenetics, the stem cell theory, or the Warburg effect.
Brücher Björn L.D.M., Jamall Ijaz S.
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International Journal of General Medicine, 2023 Sheng Liu,1,* Guanyun Shi,1 Zhengbo Pan,1 Weisong Cheng,1 Linfei Xu,1 Xingzhang Lin,1 Yongfeng Lin,1 Liming Zhang,1 Guanghua Ji,1 Xin Lv,1 Dongguo Wang2,* 1Department of Urinary Surgery, Taizhou Municipal Hospital Affiliated with Taizhou ...
Liu S +10 more
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Acta Biochimica et Biophysica SinicaIn eukaryotic cells, gene expression begins with transcription in the nucleus, followed by the maturation of messenger RNAs (mRNAs). These mRNA molecules are then exported to the cytoplasm through the nuclear pore complex (NPC), a process that serves as a critical regulatory phase of gene expression.
Chen Suli +3 more
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The Development of mRNA Vaccines for Infectious Diseases: Recent Updates
Infection and Drug Resistance, 2021 Nitika,1,2 Jiao Wei,1,2 Ai-Min Hui1,2 1Fosun Pharma USA Inc., Boston, MA, USA; 2Shanghai Fosun Pharmaceutical Industrial Development, Co., Ltd., Shanghai, People’s Republic of ChinaCorrespondence: Ai-Min HuiShanghai Fosun Pharmaceutical Industrial ...
Nitika, Wei J, Hui AM
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