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Yeast Sm-like proteins function in mRNA decapping and decay [PDF]

open access: yesNature, 2000
One of the main mechanisms of messenger RNA degradation in eukaryotes occurs by deadenylation-dependent decapping which leads to 5'-to-3' decay1, 2. A family of Sm-like (Lsm) proteins has been identified, members of which contain the 'Sm' sequence motif,
Jean Beggs   +2 more
exaly   +2 more sources

An essential component of the decapping enzyme required for normal rates of mRNA turnover

open access: yesNature, 1996
A MAJOR pathway of messenger RNA degradation in eukaryotic cells is initiated by shortening of the poly(A) tail, which, at least in yeast, triggers a decapping reaction, thereby exposing the mRNA to 5′→ 3′ degradation1–4.
Roy Parker, Audrey Stevens
exaly   +3 more sources
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Mechanisms And Control Of mRNA Decapping in Saccharomyces cerevisiae

Annual Review of Biochemistry, 2000
Roy Parker, M Tucker
exaly  

Structural and functional control of the eukaryotic mRNA decapping machinery

Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms, 2013
Haiwei Song   +2 more
exaly  

Monitoring mRNA Decapping Activity

Methods, 1999
Stuart W Peltz   +2 more
exaly  

A novel mRNA‐decapping activity in HeLa cytoplasmic extracts is regulated by AU‐rich elements

EMBO Journal, 2001
Jeffrey Wilusz   +2 more
exaly  

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