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Yeast Sm-like proteins function in mRNA decapping and decay [PDF]
One of the main mechanisms of messenger RNA degradation in eukaryotes occurs by deadenylation-dependent decapping which leads to 5'-to-3' decay1, 2. A family of Sm-like (Lsm) proteins has been identified, members of which contain the 'Sm' sequence motif,
Jean Beggs +2 more
exaly +2 more sources
An essential component of the decapping enzyme required for normal rates of mRNA turnover
A MAJOR pathway of messenger RNA degradation in eukaryotic cells is initiated by shortening of the poly(A) tail, which, at least in yeast, triggers a decapping reaction, thereby exposing the mRNA to 5′→ 3′ degradation1–4.
Roy Parker, Audrey Stevens
exaly +3 more sources
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Mechanisms And Control Of mRNA Decapping in Saccharomyces cerevisiae
Annual Review of Biochemistry, 2000Roy Parker, M Tucker
exaly
Structural and functional control of the eukaryotic mRNA decapping machinery
Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms, 2013Haiwei Song +2 more
exaly
Isolation and characterization of Dcp1p, the yeast mRNA decapping enzyme
EMBO Journal, 1998Roy Parker
exaly
The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases
EMBO Journal, 2002Megerditch Kiledjian, Xinfu Jiao
exaly
A novel mRNA‐decapping activity in HeLa cytoplasmic extracts is regulated by AU‐rich elements
EMBO Journal, 2001Jeffrey Wilusz +2 more
exaly

