Analysis of mRNA m6A modification and mRNA expression profiles in middle ear cholesteatoma
Introduction: Middle ear cholesteatoma is characterized by the hyperproliferation of keratinocytes. In recent decades, N6-methyladenosine (m6A) modification has been shown to play an essential role in the pathogenesis of many proliferative diseases ...
Shumin Xie +6 more
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Identification of lncRNA and mRNA Expression Profile in Relapsed Graves’ Disease [PDF]
Background: Graves’ disease (GD) is a common autoimmune disease, and its pathogenesis is unclear. Studies have found that the occurrence of GD is related to the immune disorder caused by the interaction of genetic susceptibility and environmental factors.
Qiuming Yao +5 more
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CYP2C8 and CYP2C9 mRNA expression profile in the human fetus [PDF]
CYP2C8 and CYP2C9 are involved in the inactivation of several NSAIDs, including ibuprofen. CYP2C9 is the major form in human liver whereas CYP2C8 has been proposed to be the main CYP2C enzyme in fetal liver.
Maria eJohansson +3 more
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The mRNA Expression Profile of Psoriatic Lesion Distinct from Non-Lesion [PDF]
Xinhua Li,1 Jianxiao Xing,1 Fangdi Wang,1 Juan Li,1 Junqin Li,1 Ruixia Hou,1 Kaiming Zhang2 1Shanxi Key Laboratory of Stem Cell for Immunological Dermatosis, Taiyuan Central Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, 030009, People ...
Li X +6 more
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Characterize Protein Functional Relationships Based on Mrna Expression Profile [PDF]
INTRODUCTION. Protein families are distinguished by members that exhibit sequence and biomedical function similarity. For most gene changes in protein abundance are related to changes in mRNA abundance, which are immensely informative about cell state and the activity of genes.
Wei Ding +4 more
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Anionic Complex with Efficient Expression and Good Safety Profile for mRNA Delivery
We previously found that a complex comprising plasmid DNA (pDNA), polyethylenimine (PEI), and γ-polyglutamic acid (γ-PGA) had high transgene efficiency without cytotoxicity in vitro and in vivo.
Eri Hamada +7 more
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Nutrient supply affects the mRNA expression profile of the porcine skeletal muscle [PDF]
Background The genetic basis of muscle fat deposition in pigs is not well known. So far, we have only identified a limited number of genes involved in the absorption, transport, storage and catabolism of lipids.
Tainã Figueiredo Cardoso +7 more
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A Transformative Technology Linking Patient’s mRNA Expression Profile to Anticancer Drug Efficacy
As precision medicine such as targeted therapy and immunotherapy often have limited accessibility, low response rate, and evolved resistance, it is urgent to develop simple, low-cost, and quick-turnaround personalized diagnostic technologies for drug ...
Chen Yeh, Shu-Ti Lin, Hung-Chih Lai
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Tissue-specific mRNA expression profile of ESR2 gene in goat [PDF]
Objective Estimates show that in the world about 30 million goats and in Iran about five million Cashmere goat are bred. One of the most important of these breeds is the Raini Cashmere goat.
Mohammadreza Mohammadabadi
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Tissue-specific mRNA expression profile of BMP15 gene in goat [PDF]
Objective Three fecundity genes have been identified, namely bone morphogenetic protein receptor type 1B (BMPR1B; or activin-like kinase 6, ALK6) known as FecB on chromosome 6, growth differentiation factor 9 (GDF9) known as FecG on chromosome 5, and ...
Mohammadreza Mohammadabadi +1 more
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