Results 1 to 10 of about 664,318 (297)

Classifying Gene Expression Profiles from Pairwise mRNA Comparisons [PDF]

Statistical Applications in Genetics and Molecular Biology, 2004
We present a new approach to molecular classification based on mRNA comparisons. Our method, referred to as the top-scoring pair(s) (TSP) classifier, is motivated by current technical and practical limitations in using gene expression microarray data for class prediction, for example to detect disease, identify tumors or predict treatment response ...
Geman, Donald, d'Avignon, Christian, Naiman, Daniel Q., Winslow, Raimond L.   +3 more
openaire   +2 more sources

Oxidized LDL induces alternative macrophage phenotype through activation of CD36 and PAFR [PDF]

, 2013
OxLDL is recognized by macrophage scavenger receptors, including CD36; we have recently found that Platelet-Activating Factor Receptor (PAFR) is also involved.
Ferracini, M., Gidlund, M., Jancar, S., Koga, M.M., Pecenin, M., Rios, F.J.   +5 more
core   +3 more sources

The Potential Roles of Long Noncoding RNAs (lncRNA) in Glioblastoma Development [PDF]

, 2016
Long noncoding RNA (lncRNA) may contribute to the initiation and progression of tumor. In this study, we first systematically compared lncRNA and mRNA expression between glioblastoma and paired normal brain tissues using microarray data.
Eischen, Christine M., Fan, Wenhong, Liu, Shuang, Mitra, Ramkrishna, Yin, Feng, Zhao, Ming-Ming, Zhao, Zhongming   +6 more
core   +2 more sources

Expression profile of lncRNAs and mRNAs in intestinal macrophages

Molecular Medicine Reports, 2020
Non-coding RNAs (ncRNAs) have been previously reported to serve an important role in transcription. In addition, several studies have revealed that long ncRNAs (lncRNAs) have a crucial role in human diseases. However, the association between lncRNAs and inflammation‑induced intestinal macrophages in the intestinal mucosal barrier has remained elusive ...
Naseer, Qais Ahmad, Liu, Lulu, Xue, Xiaofei, Chen, Siche, Chen, Jixiang, Qu, Jianguo, Cui, Lei, Wang, Xiaogang, Dang, Shengchun   +8 more
openaire   +3 more sources

Antinociceptive Effects of Intrathecal Landiolol Injection in a Rat Formalin Pain Model [PDF]

, 2012
Perioperative beta-blocker administration has recently been recommended for patients undergoing cardiac or other surgery due to the beneficial cardiovascular effects of these agents.
Itano, Yoshitaro, Kaku, Ryuji, Kanzaki, Hirotaka, Matsuoka, Yoshikazu, Mizobuchi, Satoshi, Morita, Kiyoshi, Nishie, Hiroyuki, Obata, Norihiko, Ouchida, Mamoru, Taniguchi, Arata, Tomotsuka, Naoto   +10 more
core   +1 more source

Transcriptional profiling reveals extraordinary diversity among skeletal muscle tissues [PDF]

, 2018
Skeletal muscle comprises a family of diverse tissues with highly specialized functions. Many acquired diseases, including HIV and COPD, affect specific muscles while sparing others.
Andrade, Francisco, Douglas, Collin M, Esser, Karyn A, Gong, Ming C, Gutierrez-Monreal, Miguel A, Hoffmann, Christy, Hughes, Laura D, Hughes, Michael E, Lahens, Nicholas F, Lewis, Scott A, Li, Jiajia, Riley, Lance A, Terry, Erin E, Wallace, Matthew J, Zhang, Xiping   +14 more
core   +4 more sources

MicroRNA–mRNA expression profiles associated with medulloblastoma subgroup 4

Cancer Management and Research, 2018
Medulloblastoma (MB), the most common malignant brain tumor in children, is divided into four tumor subgroups: wingless-type (WNT), sonic hedgehog (SHH), Group 3, and Group 4. Ideally, clinical practice and treatment design should be subgroup specific. While WNT and SHH subgroups have well-defined biomarkers, distinguishing Group 3 from Group 4 is not ...
Sivan Gershanov, Helen Toledano, Shalom Michowiz, Orit Barinfeld, Albert Pinhasov, Nitza Goldenberg-Cohen, Mali Salmon-Divon   +6 more
openaire   +5 more sources

Comprehensive Analysis and Co-Expression Network of mRNAs and lncRNAs in Pressure Overload-Induced Heart Failure

Frontiers in Genetics, 2019
Aim: Heart failure (HF) is the end stage of various cardiovascular diseases. However, the precise regulation of gene expression profiles and functional mechanisms of long non-coding RNAs (lncRNAs) in HF remain to be elucidated. The present study aimed to
Shuping Chen, Qiong Ma, Yanbo Xue, Jingwen Zhang, Guodong Yang, Tingzhong Wang, Tingzhong Wang, Tingzhong Wang, Aiqun Ma, Aiqun Ma, Aiqun Ma, Ling Bai   +11 more
doaj   +1 more source

Elucidating the Molecular Mechanism of Ischemic Stroke Using Integrated Analysis of miRNA, mRNA, and lncRNA Expression Profiles

Frontiers in Integrative Neuroscience, 2021
Objective: This study aimed to investigate the possible molecular mechanisms associated with ischemic stroke through the construction of a lncRNA-miRNA-mRNA network.
Yaxuan Sun, Jing Wang, Bin Han, Kun Meng, Yan Han, Yongxia Ding   +5 more
doaj   +1 more source

Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells [PDF]

, 2012
It is now recognized that small noncoding RNA sequences have the ability to mediate transcriptional activation of specific target genes in human cells.
Alluin, J, Habib, N, Kasahara, N, Mintz, P, Rossi, J, Sun, G, Sætrom, P, Voutila, J   +7 more
core   +4 more sources