Results 1 to 10 of about 5,429,710 (293)

Analysis of mRNA m6A modification and mRNA expression profiles in middle ear cholesteatoma

open access: yesFrontiers in Genetics, 2023
Introduction: Middle ear cholesteatoma is characterized by the hyperproliferation of keratinocytes. In recent decades, N6-methyladenosine (m6A) modification has been shown to play an essential role in the pathogenesis of many proliferative diseases ...
Shumin Xie   +6 more
doaj   +5 more sources

Identification of lncRNA and mRNA Expression Profile in Relapsed Graves’ Disease [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2021
Background: Graves’ disease (GD) is a common autoimmune disease, and its pathogenesis is unclear. Studies have found that the occurrence of GD is related to the immune disorder caused by the interaction of genetic susceptibility and environmental factors.
Qiuming Yao   +5 more
doaj   +5 more sources

CYP2C8 and CYP2C9 mRNA expression profile in the human fetus [PDF]

open access: yesFrontiers in Genetics, 2014
CYP2C8 and CYP2C9 are involved in the inactivation of several NSAIDs, including ibuprofen. CYP2C9 is the major form in human liver whereas CYP2C8 has been proposed to be the main CYP2C enzyme in fetal liver.
Maria eJohansson   +3 more
doaj   +5 more sources

The mRNA Expression Profile of Psoriatic Lesion Distinct from Non-Lesion [PDF]

open access: yesClinical, Cosmetic and Investigational Dermatology, 2022
Xinhua Li,1 Jianxiao Xing,1 Fangdi Wang,1 Juan Li,1 Junqin Li,1 Ruixia Hou,1 Kaiming Zhang2 1Shanxi Key Laboratory of Stem Cell for Immunological Dermatosis, Taiyuan Central Hospital of Shanxi Medical University, Taiyuan, Shanxi Province, 030009, People ...
Li X   +6 more
doaj   +2 more sources

Characterize Protein Functional Relationships Based on Mrna Expression Profile [PDF]

open access: yesThe Scientific World Journal, 2002
INTRODUCTION. Protein families are distinguished by members that exhibit sequence and biomedical function similarity. For most gene changes in protein abundance are related to changes in mRNA abundance, which are immensely informative about cell state and the activity of genes.
Wei Ding   +4 more
doaj   +3 more sources

Anionic Complex with Efficient Expression and Good Safety Profile for mRNA Delivery

open access: yesPharmaceutics, 2021
We previously found that a complex comprising plasmid DNA (pDNA), polyethylenimine (PEI), and γ-polyglutamic acid (γ-PGA) had high transgene efficiency without cytotoxicity in vitro and in vivo.
Eri Hamada   +7 more
doaj   +3 more sources

Nutrient supply affects the mRNA expression profile of the porcine skeletal muscle [PDF]

open access: yesBMC Genomics, 2017
Background The genetic basis of muscle fat deposition in pigs is not well known. So far, we have only identified a limited number of genes involved in the absorption, transport, storage and catabolism of lipids.
Tainã Figueiredo Cardoso   +7 more
doaj   +2 more sources

A Transformative Technology Linking Patient’s mRNA Expression Profile to Anticancer Drug Efficacy

open access: yesOnco
As precision medicine such as targeted therapy and immunotherapy often have limited accessibility, low response rate, and evolved resistance, it is urgent to develop simple, low-cost, and quick-turnaround personalized diagnostic technologies for drug ...
Chen Yeh, Shu-Ti Lin, Hung-Chih Lai
doaj   +3 more sources

Tissue-specific mRNA expression profile of ESR2 gene in goat [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2021
Objective Estimates show that in the world about 30 million goats and in Iran about five million Cashmere goat are bred. One of the most important of these breeds is the Raini Cashmere goat.
Mohammadreza Mohammadabadi
doaj   +1 more source

Tissue-specific mRNA expression profile of BMP15 gene in goat [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2020
Objective Three fecundity genes have been identified, namely bone morphogenetic protein receptor type 1B (BMPR1B; or activin-like kinase 6, ALK6) known as FecB on chromosome 6, growth differentiation factor 9 (GDF9) known as FecG on chromosome 5, and ...
Mohammadreza Mohammadabadi   +1 more
doaj   +1 more source

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