Results 31 to 40 of about 5,749,254 (300)

Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system [PDF]

, 2015
This work was supported by Medical Research Scotland (FRG353 to VAS), the FP7- Directorate-General for Research and Innovation of the European Commission (EU HEALTHF4-2012-305033 to Coordinating Action Systems Medicine to DJH); the Chief Scientist Office
Smith, V. Anne, Um, In Hwa, Harrison, David J, Langdon, Simon, Smith, V Anne, Koussounadis, Antonis, Harrison, David James, Langdon, Simon P., Um, In Hwa; id_orcid, Harrison, David James; id_orcid, Smith, V Anne; id_orcid   +10 more
core   +1 more source

Post-transcriptional regulation of 5-lipoxygenase mRNA expression via alternative splicing and nonsense-mediated mRNA decay [PDF]

, 2012
5-Lipoxygenase (5-LO) catalyzes the two initial steps in the biosynthesis of leukotrienes (LT), a group of inflammatory lipid mediators derived from arachidonic acid.
Laura Pufahl (182448), Manuel Grez, Grez, Manuel, Ochs, Meike J., Sorg, Bernd L., Beatrix Suess (17019), Sorg Bernd L., Laura Pufahl, Sorg, Bernd Lothar, Bernd L Sorg, Beatrix Suess, Bernd L. Sorg (182441), Suess Beatrix, Grez Manuel, Steinhilber Dieter, Dieter Steinhilber (182458), Meike J. Ochs (182432), Suess, Beatrix, Manuel Grez (182453), Dieter Steinhilber, Meike J Ochs, Pufahl, Laura, Süß, Beatrix, Pufahl Laura, Ochs, Meike, Steinhilber, Dieter, Ochs Meike J.   +26 more
core   +2 more sources

HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis [PDF]

Nucleic Acids Research, 2012
The HemaExplorer (http://servers.binf.ku.dk/hemaexplorer) is a curated database of processed mRNA Gene expression profiles (GEPs) that provides an easy display of gene expression in haematopoietic cells. HemaExplorer contains GEPs derived from mouse/human haematopoietic stem and progenitor cells as well as from more differentiated cell types. Moreover,
Frederik Otzen Bagger, Nicolas Rapin, Kim Theilgaard-Mönch, Bogumil Kaczkowski, Lina A. Thoren, Johan Jendholm, Ole Winther, Bo T. Porse   +7 more
openaire   +6 more sources

LncRNA‐mRNA expression profiles and functional networks in osteoclast differentiation [PDF]

Journal of Cellular and Molecular Medicine, 2020
AbstractHuman osteoclasts are differentiated from CD14+ monocytes and are responsible for bone resorption. Long non‐coding RNAs (lncRNAs) have been proved to be significantly involved in multiple biologic processes, especially in cell differentiation. However, the effect of lncRNAs in osteoclast differentiation is less appreciated.
Wenjie Liu, Zhaofeng Li, Zhaopeng Cai, Zhongyu Xie, Jinteng Li, Ming Li, Shuizhong Cen, Su'an Tang, Guan Zheng, Guiwen Ye, Hongjun Su, Shan Wang, Peng Wang, Huiyong Shen, Yanfeng Wu   +14 more
openaire   +2 more sources

The mRNA expression of hTERT in human breast carcinomas correlates with VEGF expression [PDF]

, 2004
Background Telomerase is a ribonucleoprotein enzyme that synthesises telomeres after cell division and maintains chromosomal stability leading to cellular immortalisation.
Newbold, RF, Kirkpatrick, KL, Mokbel, K
core   +1 more source

Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast [PDF]

, 2007
Splicing of pre-mRNA is a critical step in mRNA maturation and disturbances cause several genetic disorders. We apply the synthetic tetracycline (tc)-binding riboswitch to establish a gene expression system for conditional tc-dependent control of pre ...
Weigand, Julia E., Suess, Beatrix, Weigand, Julia, Süß, Beatrix   +3 more
core   +1 more source

Genome‑wide profiling of lncRNA and mRNA expression in CRSwNP

Molecular Medicine Reports, 2019
Chronic rhinosinusitis with nasal polyps (CRSwNP) is one of the most prevalent chronic diseases. In patients with CRSwNP, the present study performed comprehensive bioinformatics analyses to characterize the transcriptome profiles of mRNAs and long non‑coding RNAs (lncRNAs). A total of 265 differentially expressed lncRNAs and 994 mRNAs were identified.
Minglei, Liu, Ping, Guo, Jun, An, Chao, Guo, Fengxiang, Lu, Yanhua, Lei   +5 more
openaire   +3 more sources

Genome-wide expression profiling of in vivo-derived bloodstream parasite stages and dynamic analysis of mRNA alterations during synchronous differentiation in Trypanosoma brucei [PDF]

, 2009
Background: Trypanosomes undergo extensive developmental changes during their complex life cycle. Crucial among these is the transition between slender and stumpy bloodstream forms and, thereafter, the differentiation from stumpy to tsetse-midgut ...
Ross Alan, Sarah Kabani, Katelyn Fenn, Keith Matthews, Matthews Keith, Kabani, Sarah, Matthews, Keith; id_orcid, Terry K Smith, Ghazal, Peter, Fenn Katelyn, Al Ivens, Smith Terry K, Smith, Terry K., Ghazal Peter, Kabani Sarah, Smith, Terry K, Ross, Alan, Fenn, Katelyn, Peter Ghazal, Ivens, Al, Matthews, Keith, Ivens Al, Alan Ross, Smith, Terry K.; id_orcid   +23 more
core   +1 more source

miRTarVis: an interactive visual analysis tool for microRNA-mRNA expression profile data. [PDF]

BMC Proc, 2015
Background MicroRNAs (miRNA) are short nucleotides that down-regulate its target genes. Various miRNA target prediction algorithms have used sequence complementarity between miRNA and its targets.
Jung D, Kim B, Freishtat RJ, Giri M, Hoffman E, Seo J.   +5 more
europepmc   +4 more sources

Altered expression of mRNA profiles in blood of early-onset schizophrenia [PDF]

Scientific Reports, 2016
AbstractTo identify gene expression abnormalities in schizophrenia (SZ), we generated whole-genome gene expression profiles using microarrays on peripheral blood mononuclear cells (PBMCs) from 18 early-onset SZ cases and 12 controls. We detected 84 transcripts differentially expressed by diagnostic status, with 82 genes being upregulated and 2 ...
Yong Xu, Yin Yao Shugart, Guoqiang Wang, Zaohuo Cheng, Chunhui Jin, Kai Zhang, Jun Wang, Hao Yu, Weihua Yue, Fuquan Zhang, Dai Zhang   +10 more
openaire   +2 more sources