Results 21 to 30 of about 664,318 (297)

Integrated ordination of miRNA and mRNA expression profiles [PDF]

BMC Genomics, 2015
Several studies have investigated miRNA and mRNA co-expression to identify regulatory networks at the transcriptional level. A typical finding of these studies is the presence of both negative and positive miRNA-mRNA correlations. Negative correlations are consistent with the expected, faster degradation of target mRNAs, whereas positive correlations ...
DIAZ, GIACOMO, Zamboni, Fausto, Tice, Ashley, FARCI, PATRIZIA   +3 more
openaire   +2 more sources

Insight into Liver lncRNA and mRNA Profiling at Four Developmental Stages in Ningxiang Pig

Biology, 2021
Ningxiang pigs, a fat-type pig, are native to Ningxiang County in Hunan Province, with thousands of years of breeding history. This study aims to explore the expression profiles and functional networks on messenger RNAs (mRNAs) and long non-coding RNAs ...
Yan Gong, Yuebo Zhang, Biao Li, Yu Xiao, Qinghua Zeng, Kang Xu, Yehui Duan, Jianhua He, Haiming Ma   +8 more
doaj   +1 more source

Expression profile of mRNAs from human pancreatic islet tumors [PDF]

Journal of Molecular Endocrinology, 2003
In order to understand the tIssue specificity of the endocrine pancreas, it is important to clarify the expression profile of mRNAs in various states of the tIssue. A total of approximately 9000 non-redundant expressed genes from human pancreatic islets and insulinoma have so far been determined as expressed sequence tags (ESTs) and deposited in public
L, Jin, H, Wang, T, Narita, R, Kikuno, O, Ohara, N, Shihara, T, Nishigori, Y, Horikawa, J, Takeda   +8 more
openaire   +2 more sources

Importin α mRNAs have distinct expression profiles during spermatogenesis [PDF]

Developmental Dynamics, 2005
AbstractImportin proteins control access to the cell nucleus by mediating the nuclear transport of specific cargoes. We hypothesized that developmental regulation of gene expression may be partially effected by changes in the nuclear transport machinery complement, manifested as regulated expression of importin α family genes.
Cathryn A, Hogarth, Sophina, Calanni, David A, Jans, Kate L, Loveland   +3 more
openaire   +2 more sources

Using mRNA expression profiling to determine anticancer drug efficacy [PDF]

Cytometry, 2001
AbstractPharmacogenomics is a fast‐growing field of investigations that aims to further elucidate the inherited nature of interindividual differences in drug disposition and effects, with the ultimate goal of providing a stronger scientific basis for selecting the optimal drug therapy.
Gerrit, Los, Fei, Yang, Goli, Samimi, Gerald, Manorek, Ivelina M, Guerorguieva, Stephan, Howell, Nielka, van Erp, James K, Breaux   +7 more
openaire   +2 more sources

Tissue-specific mRNA expression profiling in grape berry tissues [PDF]

BMC Genomics, 2007
AbstractBackgroundBerries of grape (Vitis vinifera) contain three major tissue types (skin, pulp and seed) all of which contribute to the aroma, color, and flavor characters of wine. The pericarp, which is composed of the exocarp (skin) and mesocarp (pulp), not only functions to protect and feed the developing seed, but also to assist in the dispersal ...
Grimplet, Jerome, Deluc, Laurent G., Tillett, Richard L., Wheatley, Matthew D., Schlauch, Karen A., Cramer, Grant R., Cushman, John C.   +6 more
openaire   +4 more sources

Expression profiling of metalloproteinases and tissue inhibitors of metalloproteinases in normal and degenerate human achilles tendon [PDF]

, 2006
To profile the messenger RNA (mRNA) expression for the 23 known genes of matrix metalloproteinases (MMPs), 19 genes of ADAMTS, 4 genes of tissue inhibitors of metalloproteinases (TIMPs), and ADAM genes 8, 10, 12, and 17 in normal, painful, and ruptured ...
Alfredson, Alfredson, Amour, Amour, Anthony N. Corps, Archambault, Arnoczky, Asakura, Astrom, Baker, BenEzra, Bjur, Black, Brew, Brian L. Hazleman, Caroline J. Pennington, Cawston, Clancy, Conover, Dickinson, Drummond, Dylan R. Edwards, Fenwick, Gavin C. Jones, Graham P. Riley, Hannafin, Hashimoto, Hieta, Ian M. Clark, Iba, Iba, Ireland, Jarvinen, Jones, Jozsa, Kannus, Kashiwagi, Kashiwagi, Killar, Kurisaki, Lavagnino, Lo, Loechel, Ma, Majima, Malfait, Michelle M. Bradley, Movin, Mueller, Muller, Nakamura, Nuttall, Pei, Pendas, Porter, Primakoff, Rees, Riley, Riley, Riley, Roy, Sandy, Sandy, Sedlacek, Somerville, Sternlicht, Thodeti, Tipton, Tsuzaki, Van Meurs, Van Meurs, Velasco, Yasuda, Yu   +73 more
core   +1 more source

Expression Profiles of Mouse Kell, XK, and XPLAC mRNA [PDF]

Journal of Histochemistry & Cytochemistry, 2007
Kell and XK are related because in red cells they exist as a disulfide-bonded complex. Kell is an endothelin-3-converting enzyme, and XK is predicted to be a transporter. Absence of XK, which is accompanied by reduced Kell on red cells, results in acanthocytosis and late-onset forms of central nervous system and neuromuscular abnormalities that ...
Soohee, Lee, Quan, Sha, Xu, Wu, Giulia, Calenda, Jianbin, Peng   +4 more
openaire   +2 more sources

Platelet Gene Expression as a Biomarker Risk Stratification Tool in Acute Myocardial Infarction: A Pilot Investigation

Clinical Medicine Insights: Blood Disorders, 2010
Platelets play a major role in the pathophysiology of acute myocardial infarction (AMI). Recent evidence reveals megakaryocyte-derived platelet pre-mRNA is spliced to mRNA and then translated into functional proteins in response to external stimulation ...
David C. Calverley, Ivan P. Casserly, Qamrul G. Choudhury, Tzu L. Phang, Bifeng Gao, John C. Messenger, Mark W. Geraci   +6 more
doaj   +2 more sources

Generation and characterization of a mouse line for monitoring translation in dopaminergic neurons [PDF]

, 2017
We developed a mouse line targeting midbrain dopamine neurons for Translating Ribosome Affinity Purification(TRAP). Here, we briefly report on the basic characterization of this mouse line including confirmation of expression of the transgene in midbrain
Dougherty, Joseph D
core   +2 more sources