Results 21 to 30 of about 5,429,710 (293)

An Integrated Analysis of miRNA, lncRNA, and mRNA Expression Profiles [PDF]

BioMed Research International, 2014
Increasing amounts of evidence indicate that noncoding RNAs (ncRNAs) have important roles in various biological processes. Here, miRNA, lncRNA, and mRNA expression profiles were analyzed in human HepG2 and L02 cells using high-throughput technologies.
Guo, Li, Zhao, Yang, Yang, Sheng, Zhang, Hui, Chen, Feng   +4 more
openaire   +2 more sources

The mRNA expression of hTERT in human breast carcinomas correlates with VEGF expression [PDF]

, 2004
Background Telomerase is a ribonucleoprotein enzyme that synthesises telomeres after cell division and maintains chromosomal stability leading to cellular immortalisation.
Newbold, RF, Kirkpatrick, KL, Mokbel, K
core   +1 more source

Platelet Gene Expression as a Biomarker Risk Stratification Tool in Acute Myocardial Infarction: A Pilot Investigation

Clinical Medicine Insights: Blood Disorders, 2010
Platelets play a major role in the pathophysiology of acute myocardial infarction (AMI). Recent evidence reveals megakaryocyte-derived platelet pre-mRNA is spliced to mRNA and then translated into functional proteins in response to external stimulation ...
David C. Calverley, Ivan P. Casserly, Qamrul G. Choudhury, Tzu L. Phang, Bifeng Gao, John C. Messenger, Mark W. Geraci   +6 more
doaj   +2 more sources

Post-transcriptional regulation of 5-lipoxygenase mRNA expression via alternative splicing and nonsense-mediated mRNA decay [PDF]

, 2012
5-Lipoxygenase (5-LO) catalyzes the two initial steps in the biosynthesis of leukotrienes (LT), a group of inflammatory lipid mediators derived from arachidonic acid.
Laura Pufahl (182448), Manuel Grez, Grez, Manuel, Ochs, Meike J., Sorg, Bernd L., Beatrix Suess (17019), Sorg Bernd L., Laura Pufahl, Sorg, Bernd Lothar, Bernd L Sorg, Beatrix Suess, Bernd L. Sorg (182441), Suess Beatrix, Grez Manuel, Steinhilber Dieter, Dieter Steinhilber (182458), Meike J. Ochs (182432), Suess, Beatrix, Manuel Grez (182453), Dieter Steinhilber, Meike J Ochs, Pufahl, Laura, Süß, Beatrix, Pufahl Laura, Ochs, Meike, Steinhilber, Dieter, Ochs Meike J.   +26 more
core   +2 more sources

HemaExplorer: a database of mRNA expression profiles in normal and malignant haematopoiesis [PDF]

Nucleic Acids Research, 2012
The HemaExplorer (http://servers.binf.ku.dk/hemaexplorer) is a curated database of processed mRNA Gene expression profiles (GEPs) that provides an easy display of gene expression in haematopoietic cells. HemaExplorer contains GEPs derived from mouse/human haematopoietic stem and progenitor cells as well as from more differentiated cell types. Moreover,
Frederik Otzen Bagger, Nicolas Rapin, Kim Theilgaard-Mönch, Bogumil Kaczkowski, Lina A. Thoren, Johan Jendholm, Ole Winther, Bo T. Porse   +7 more
openaire   +6 more sources

LncRNA‐mRNA expression profiles and functional networks in osteoclast differentiation [PDF]

Journal of Cellular and Molecular Medicine, 2020
AbstractHuman osteoclasts are differentiated from CD14+ monocytes and are responsible for bone resorption. Long non‐coding RNAs (lncRNAs) have been proved to be significantly involved in multiple biologic processes, especially in cell differentiation. However, the effect of lncRNAs in osteoclast differentiation is less appreciated.
Wenjie Liu, Zhaofeng Li, Zhaopeng Cai, Zhongyu Xie, Jinteng Li, Ming Li, Shuizhong Cen, Su'an Tang, Guan Zheng, Guiwen Ye, Hongjun Su, Shan Wang, Peng Wang, Huiyong Shen, Yanfeng Wu   +14 more
openaire   +2 more sources

Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system [PDF]

, 2015
This work was supported by Medical Research Scotland (FRG353 to VAS), the FP7- Directorate-General for Research and Innovation of the European Commission (EU HEALTHF4-2012-305033 to Coordinating Action Systems Medicine to DJH); the Chief Scientist Office
Smith, V. Anne, Um, In Hwa, Harrison, David J, Langdon, Simon, Smith, V Anne, Koussounadis, Antonis, Harrison, David James, Langdon, Simon P.   +7 more
core   +1 more source

Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast [PDF]

, 2007
Splicing of pre-mRNA is a critical step in mRNA maturation and disturbances cause several genetic disorders. We apply the synthetic tetracycline (tc)-binding riboswitch to establish a gene expression system for conditional tc-dependent control of pre ...
Weigand, Julia E., Suess, Beatrix, Weigand, Julia, Süß, Beatrix   +3 more
core   +1 more source

Genome‑wide profiling of lncRNA and mRNA expression in CRSwNP

Molecular Medicine Reports, 2019
Chronic rhinosinusitis with nasal polyps (CRSwNP) is one of the most prevalent chronic diseases. In patients with CRSwNP, the present study performed comprehensive bioinformatics analyses to characterize the transcriptome profiles of mRNAs and long non‑coding RNAs (lncRNAs). A total of 265 differentially expressed lncRNAs and 994 mRNAs were identified.
Minglei, Liu, Ping, Guo, Jun, An, Chao, Guo, Fengxiang, Lu, Yanhua, Lei   +5 more
openaire   +3 more sources

Comprehensive Analysis and Co-Expression Network of mRNAs and lncRNAs in Pressure Overload-Induced Heart Failure

Frontiers in Genetics, 2019
Aim: Heart failure (HF) is the end stage of various cardiovascular diseases. However, the precise regulation of gene expression profiles and functional mechanisms of long non-coding RNAs (lncRNAs) in HF remain to be elucidated. The present study aimed to
Shuping Chen, Qiong Ma, Yanbo Xue, Jingwen Zhang, Guodong Yang, Tingzhong Wang, Tingzhong Wang, Tingzhong Wang, Aiqun Ma, Aiqun Ma, Aiqun Ma, Ling Bai   +11 more
doaj   +1 more source