Results 11 to 20 of about 5,429,710 (293)

MMpred: functional miRNA – mRNA interaction analyses by miRNA expression prediction [PDF]

open access: yes, 2012
Background: MicroRNA (miRNA) directed gene repression is an important mechanism of posttranscriptional regulation. Comprehensive analyses of how microRNA influence biological processes requires paired miRNA-mRNA expression datasets.
Wilson, Paul   +5 more
core   +8 more sources

Profile of PD-L1 mRNA Expression in Childhood Acute Leukemia

open access: yesAsian Pacific Journal of Cancer Biology, 2021
Background: Programmed Death Ligand 1 (PD-L1) expression was used to determine type of patients who respond to immunotherapy using immune checkpoint inhibitor in several solid malignancies. However, the role of PD-L1 in hematological malignancies is less
Muhammad Al Azhar   +2 more
doaj   +1 more source

Integrated ordination of miRNA and mRNA expression profiles [PDF]

open access: yesBMC Genomics, 2015
Several studies have investigated miRNA and mRNA co-expression to identify regulatory networks at the transcriptional level. A typical finding of these studies is the presence of both negative and positive miRNA-mRNA correlations. Negative correlations are consistent with the expected, faster degradation of target mRNAs, whereas positive correlations ...
DIAZ, GIACOMO   +3 more
openaire   +2 more sources

Integrated analysis of microRNA and mRNA expression profiles in Preeclampsia

open access: yesBMC Medical Genomics, 2023
Abstract Background Preeclampsia (PE), a pregnancy specific syndrome, is one kind of common gestational hypertension disease, which can cause maternal and perinatal mortality and morbidity. This study was conducted to identify key microRNAs (miRNAs), mRNAs and related signaling pathways in the pathogenesis of PE.
Zepeng Ping   +4 more
openaire   +3 more sources

Insight into Liver lncRNA and mRNA Profiling at Four Developmental Stages in Ningxiang Pig

open access: yesBiology, 2021
Ningxiang pigs, a fat-type pig, are native to Ningxiang County in Hunan Province, with thousands of years of breeding history. This study aims to explore the expression profiles and functional networks on messenger RNAs (mRNAs) and long non-coding RNAs ...
Yan Gong   +8 more
doaj   +1 more source

Expression profile of lncRNAs and mRNAs in intestinal macrophages

open access: yesMolecular Medicine Reports, 2020
Non-coding RNAs (ncRNAs) have been previously reported to serve an important role in transcription. In addition, several studies have revealed that long ncRNAs (lncRNAs) have a crucial role in human diseases. However, the association between lncRNAs and inflammation‑induced intestinal macrophages in the intestinal mucosal barrier has remained elusive ...
Naseer, Qais Ahmad   +8 more
openaire   +3 more sources

Expression Profiles of Mouse Kell, XK, and XPLAC mRNA [PDF]

open access: yesJournal of Histochemistry & Cytochemistry, 2007
Kell and XK are related because in red cells they exist as a disulfide-bonded complex. Kell is an endothelin-3-converting enzyme, and XK is predicted to be a transporter. Absence of XK, which is accompanied by reduced Kell on red cells, results in acanthocytosis and late-onset forms of central nervous system and neuromuscular abnormalities that ...
Soohee, Lee   +4 more
openaire   +2 more sources

Cancer-Related Ischemic Stroke Has a Distinct Blood mRNA Expression Profile

open access: yesStroke, 2019
Babak Navi   +2 more
exaly   +2 more sources

Transcriptional Profiling of mRNA Expression in the Mouse Distal Colon [PDF]

open access: yesGastroenterology, 2008
Intestinal epithelial cells and the myenteric plexus of the mouse gastrointestinal tract contain a circadian clock-based intrinsic time-keeping system. Because disruption of the biological clock has been associated with increased susceptibility to colon cancer and gastrointestinal symptoms, we aimed to identify rhythmically expressed genes in the mouse
Hoogerwerf, WA   +9 more
openaire   +3 more sources

Integrated analysis of mRNA and protein expression profiling in tubal endometriosis [PDF]

open access: yesReproduction, 2020
Abstract Tubal endometriosis (tubal EM) is a subtype of endometriosis (EM) associated with fallopian tube impairments and infertility. Since the molecular mechanism underlying tubal EM is not clear, we assume that an aberrant transcriptome of fallopian tube epithelium and microenvironment changes caused by cytokines in tubal fluid are
Qi, Hang   +6 more
openaire   +2 more sources

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