Results 51 to 60 of about 5,429,710 (293)

Consensus clustering and functional interpretation of gene-expression data [PDF]

, 2004
Microarray analysis using clustering algorithms can suffer from lack of inter-method consistency in assigning related gene-expression profiles to clusters.
Liu, X, Orengo, Christine, Martin, N, Kellam, P., Paul Kellam, Liu, X., Swift, Stephen, Swift, S, Orengo, C.A., Tucker, Allan, Tucker, A., Tucker, A, Liu, XH, Allan Tucker, Vinciotti, Veronica, Christine Orengo, Veronica Vinciotti, Vinciotti, V., Xiaohui Liu, Swift, S., Kellam, P, Liu, Xiaohui, Vinciotti, V, Stephen Swift, Kellam, Paul, Orengo, C, Martin, Nigel, Nigel Martin   +27 more
core   +1 more source

Expression profile analysis of 5-day-old neonatal piglets infected with porcine Deltacoronavirus

BMC Veterinary Research, 2019
Background Porcine deltacoronavirus (PDCoV) is a novel coronavirus that can cause diarrhea in nursing piglets. This study was aimed to investigate the roles of host differentially expressed genes on metabolic pathways in PDCoV infections.
Jiao L. Wu, Kai J. Mai, Di Li, Rui T. Wu, Zi X. Wu, Xiao Y. Tang, Qian N. Li, Yuan Sun, Tian Lan, Xiang B. Zhang, Jing Y. Ma   +10 more
doaj   +1 more source

Culture-induced changes in mRNA expression levels of efflux and SLC-transporters in brain endothelial cells

Fluids and Barriers of the CNS, 2020
Background The complexity of the neurovascular unit (NVU) poses a challenge in the investigations of drug transport across the blood–brain barrier (BBB) and the function of the brain capillary endothelium.
C. Goldeman, B. Ozgür, B. Brodin
doaj   +1 more source

Kaposin-B enhances the PROX1 mRNA stability during lymphatic reprogramming of vascular endothelial cells by Kaposi's sarcoma herpes virus. [PDF]

, 2010
Kaposi's sarcoma (KS) is the most common cancer among HIV-positive patients. Histogenetic origin of KS has long been elusive due to a mixed expression of both blood and lymphatic endothelial markers in KS tumor cells.
Kafka, Darren, Koh, Chester J., Aguilar Berenice, Yoo, Jaehyuk, Hong Young-Kwon, Hong, Young-Kwon, Lee, Sunju, Choi, Inho, Yoo Jaehyuk, Haas, Jürgen G., Kang Jinjoo, Lee Ha Neul, Swapnika Ramu, Kang, Jinjoo, Young-Kwon Hong, Juneyong Lee, Ramu, Swapnika, Darren Kafka, Lee, Juneyong, Kafka Darren, Lee Sunju, Choi Inho, Juergen Haas, Haas, Juergen, Lee Juneyong, Sunju Lee, Inho Choi, Ha Neul Lee, Haas Juergen, Aguilar, Berenice, Chester J. Koh, Jinjoo Kang, Chester J Koh, Jaehyuk Yoo, Koh Chester J., Berenice Aguilar, Ramu Swapnika, Lee, Ha Neul   +37 more
core   +1 more source

Cloning, phylogenetic analysis, tissue expression profiling, and functional roles of NPC1L1 in chickens, quails, and ducks

Poultry Science
The Niemann-Pick C1-Like 1 (NPC1L1) protein, primarily expressed in the epithelial cells of the small intestine, is essential for cholesterol absorption from both dietary intake and biliary secretion.
Xin Shu, Ziwei Chen, Hui Wang, Bingjie Xu, Li Liu, Jilong Zhang, Xiaotong Zheng, Jianfei Chen   +7 more
doaj   +1 more source

Modification of N6-methyladenosine RNA methylation on heat shock protein expression.

PLoS ONE, 2018
This study was conducted to investigate effect of N6-methyladenosine (m6A) RNA methylation on Heat shock proteins (HSPs) and dissect the profile of HSP RNA methylation. The results showed that m6A methyltransferases METTL3 mRNA was decreased in responses
Jiayao Yu, Yi Li, Tian Wang, Xiang Zhong
doaj   +1 more source

Evaluating the mRNA expression profile of APC in Pterygium

Acta Medica International, 2015
Introduction: The exact etiology of pterygium is unknown. Most of population based studies implicating that pterygium has a benign behavior rather than destructive condition. Changed expression of cell cycle-related genes may lead to the abnormal cell proliferation and finally to malignancy phenotype. The aim of this study was evaluation the expression
Maryam Najafi, DorMohammad Kordi-Tamandani, Mohammad Arish   +2 more
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Analysis of Methylation Patterns and Expression Profiles of P14 Gene in Patients with Oral Squamous Cell Carcinoma

The International Journal of Biological Markers, 2010
Aims To analyze the promoter methylation profile and mRNA expression of the p14 ARF gene in oral squamous cell carcinoma (OSCC). Methods Promoter methylation of the p14 ARF gene was investigated by methylation-specific polymerase chain reaction in ...
Dor Mohammad Kordi-Tamandani, Abdolkarim Moazeni-Roodi, Mohammad Ayoub Rigi Ladez, Mohammad Hashemi, Elnaz Birjandian, Adam Torkamanzehi   +5 more
doaj   +1 more source

Modeling miRNA-mRNA interactions that cause phenotypic abnormality in breast cancer patients.

PLoS ONE, 2017
BackgroundThe dysregulation of microRNAs (miRNAs) alters expression level of pro-oncogenic or tumor suppressive mRNAs in breast cancer, and in the long run, causes multiple biological abnormalities.
Sanghoon Lee, Xia Jiang
doaj   +1 more source