Results 101 to 110 of about 4,080 (215)

Medication-Related Osteonecrosis of the Jaw (MRONJ) [PDF]

Journal of Oral and Maxillofacial Surgery, 2021
openaire   +2 more sources

Cumulative incidence and risk factors for medication-related osteonecrosis of the jaw during long-term prostate cancer management

Scientific Reports
Bone-modifying agents (BMA) are extensively used in treating patients with prostate cancer with bone metastases. However, this increases the risk of medication-related osteonecrosis of the jaw (MRONJ).
Masaru Tani, Koji Hatano, Akihiro Yoshimura, Yuki Horibe, Yutong Liu, Nesrine Sassi, Toshiki Oka, Yohei Okuda, Akinaru Yamamoto, Toshihiro Uemura, Gaku Yamamichi, Yu Ishizuya, Yoshiyuki Yamamoto, Taigo Kato, Atsunari Kawashima, Norio Nonomura   +15 more
doaj   +1 more source

Medication-related osteonecrosis of the jaw (MRONJ)

Revista Colombiana de Ciencias Químico-Farmacéuticas
Introduction: Medication-related osteonecrosis of the jaw, formerly known as bisphosphonate-associated osteonecrosis of the jaw, is a syndrome first described in 2003. Prescription drugs such as bisphosphonates, denosumab and anti-angiogenic agents, including monoclonal antibodies, have been implicated in the development of medication-related ...
Katherine Cuenca-León, Darlin Riofrio, Santiago Reinoso-Quezada, Anabel Solano-Jara, Jaime Cuenca-León, Edisson-Mauricio Pacheco-Quito   +5 more
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Case Report: single low-dose of denosumab as a trigger of MRONJ development in a patient with osteoporosis after bisphosphonate therapy

Frontiers in Oral Health
Both denosumab (DMB) and bisphosphonates (BPs), antiresorptive drugs (ARDs) used for the treatment of osteoporosis and oncological disorders, are known for their potential to cause medication-related osteonecrosis of the jaws (MRONJ).
Dávid Száraz, Dávid Száraz, Vojtěch Peřina, Vojtěch Peřina, Jana Treglerová, Jana Treglerová, Ctirad Macháček, Ctirad Macháček, Ondřej Zendulka, Petra Bořilová Linhartová, Petra Bořilová Linhartová   +10 more
doaj   +1 more source

Prevalence and risk factors of MRONJ in breast cancer patients with CTIBL

Introduction: Patients with hormone-receptor positive breast cancer (BC) often receive Adjuvant Endocrine Therapy (AET), which can cause Cancer Treatment-Induced Bone Loss (CTIBL).
Bacci, Christian, Falci, Cristina, Roccuzzo, Francesca, Watutantrige - Fernando, Sara, Manera, Claudia, Zovato, Stefania, Boccuto, Mariagrazia   +6 more
core   +1 more source

Comprehensive profiling of plasma and exosomal microRNAs in medication-related osteonecrosis of the jaw

Scientific Reports
The role of circulating microRNAs (miRNAs) in the pathophysiology of medication-related osteonecrosis of the jaw (MRONJ) remains to be elucidated.
Sujin Oh, Minjae Park, Hyun Hwang, Jung-Hyun Park, Keun-Suh Kim, Jin-Woo Kim, Hyo-Jung Lee   +6 more
doaj   +1 more source

Early detection of medication-related osteonecrosis of the jaw (MRONJ) in patients with metastatic breast cancer using FDG-PET/CT scansResearch in context

EClinicalMedicine
Summary: Background: Patients with osseous metastatic breast cancer receive bone-modifying agents (BMAs) as part of their standard care. Medication-related osteonecrosis of the jaw (MRONJ) is one of the most important toxicities of this class of drugs ...
Miriam Emmelheinz, Daniel Egle, Samira Abdel Azim, Angela Augustin, Florentina Baumgart, Benjamin Walch, Johannes Laimer, Emanuel Bruckmoser, Lisa-Maria Rossetti, Steffen Bayerschmidt, Christian Uprimny, Marjan Arvandi, Uwe Siebert, Christian Marth, Christine Brunner   +14 more
doaj   +1 more source

Integrative Epigenomic and Targeted Protein Analysis in MRONJ: Correlating DNA Methylation with Bone Biomarkers

Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse effect of antiresorptive agents, including bisphosphonates (BPs) and denosumab (DMB).
Danxin Wang, Yan Gong, Marwa Tantawy, Villa, Alessandro, Alshammari, Raed Awadh, Joseph Katz, Wang, Danxin, Holliday, Lexie Shannon, Tantawy, Marwa, Katz, Joseph, Raed Awadh Alshammari, Gong, Yan, Elysse Castro-Hall, Castro-Hall, Elysse, Maria Abreu, Abreu, Maria, Alessandro Villa, Lexie Shannon Holliday   +17 more
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Evaluation of medication-related osteonecrosis of the jaw using the Japanese Adverse Drug Event Report database

Therapeutics and Clinical Risk Management, 2018
Ayaka Inada, Keiko Hosohata, Saki Oyama, Iku Niinomi, Yasuhiro Mori, Yuki Yamaguchi, Mayako Uchida, Kazunori Iwanaga Education and Research Center for Clinical Pharmacy, Osaka University of Pharmaceutical Sciences, Takatsuki, Osaka 569-1094, Japan ...
Inada A, Hosohata K, Oyama S, Niinomi I, Mori Y, Yamaguchi Y, Uchida M, Iwanaga K   +7 more
doaj  

Duration of Bisphosphonate administration and risk factors in MRONJ : A Retrospective study

, 2019
본 연구는 유방암과 전립선암 등 고형암환자의 골 전이와 골다공증의 예방과 치료를 위하여 비스포스포네이트를 투여한 후 MRONJ (Medication related osteonecrosis of the jaw)가 발병하여, 이화여자대학교 의료원 목동병원 구강악안면외과로 의뢰되어 2010년 1월 1일부터 2018년 8월 31일 사이에 MRONJ 확진으로 턱뼈 괴사 관련 수술적 치료를 시행 받은 유방암, 다발성 골수종, 골다공증의 기저질환이 있는 74명 중
김은실
core   +1 more source