Results 81 to 90 of about 4,080 (215)

Imbalance of Serum Bone-Metabolism-Related Factors Associated with Osteonecrosis of the Jaw

Biomedicines
Background: Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse effect of bone-modifying agents. The aim of this study was to elucidate the pathogenesis of MRONJ through a comprehensive comparison of bone-metabolism-related factors ...
Kazuyuki Yusa, Yuji Takeda, Nobuyuki Sasahara, Tomoharu Hemmi, Shigeo Ishikawa, Tsuneo Konta   +5 more
doaj   +1 more source

Factors affecting development of medication-related osteonecrosis of the jaw in cancer patients receiving high-dose bisphosphonate or denosumab therapy: Is tooth extraction a risk factor?

PLoS ONE, 2018
Methods for preventing medication-related osteonecrosis of the jaw (MRONJ) in cancer patients who have received high-dose bisphosphonate (BP) or denosumab (Dmab) have not yet been established.
Sakiko Soutome, Saki Hayashida, Madoka Funahara, Yuki Sakamoto, Yuka Kojima, Souichi Yanamoto, Masahiro Umeda   +6 more
doaj   +1 more source

Investigation of Sustained BMP Delivery in the Prevention of Medication‐Related Osteonecrosis of the Jaw (MRONJ) in a Rat Model

, 2019
Medication-related osteonecrosis of the jaw (MRONJ) poses an ongoing challenge for clinicians and researchers. Currently, there is a lack of preventative measures available for at-risk patients undergoing tooth extractions, especially those with prior ...
Laura J. Bray, Werner, Carsten, Maria A. Woodruff, Mikhail V. Tsurkan, Christina Theodoropoulos, Edward Hsu, Nikolarakos, Dimitrios, Hsu, Edward, Theodoropoulos, Christina, Tsurkan, Mikhail V, Bray, Laura J, Ren, Jiongyu, Siamak Saifzadeh, Dietmar W. Hutmacher, Brierly, Gary I, Jeremy Baldwin, Gary I. Brierly, Woodruff, Maria A, Jiongyu Ren, Dimitrios Nikolarakos, Carsten Werner, Saifzadeh, Siamak, Baldwin, Jeremy, Lynham, Anthony, Hutmacher, Dietmar W, Anthony Lynham   +25 more
core   +1 more source

Osteoclastic expression of higher-level regulators NFATc1 and BCL6 in medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy: a comparison with osteoradionecrosis and osteomyelitis

Journal of Translational Medicine, 2019
Background With an increasing indication spectrum of antiresorptive drugs, the medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy [MRONJ (BP)] is continuously gaining clinical relevance.
Falk Wehrhan, Christian Gross, Kay Creutzburg, Kerstin Amann, Jutta Ries, Marco Kesting, Carol-Immanuel Geppert, Manuel Weber   +7 more
doaj   +1 more source

Treatment of Medication-Related Osteonecrosis of the Jaws (MRONJ) with Topical Therapy Using Active Oxygen Gel [PDF]

Tatiana Miranda Deliberador, Carlos Stutz, Elisa Sartori, Leandro Kluppel, Rubens Moreno de Freitas Department of Implantology, Master’s Program, Latin American Institute of Dental Research and Education – ILAPEO, Curitiba, PR, BrazilCorrespondence ...
Stutz C, Sartori E, de Freitas RM, Kluppel L, Deliberador TM   +4 more
core  

Influence of Periodontal Infection upon the Stage of MRONJ

, 2017
학위논문(석사)--아주대학교 임상치의학대학원 :임상치의학과,2017. 8I.INTRODUCTION 5 II.PATIENTS AND METHODS 8 1.1 PATIENTS 8 1.2 METHODS 9 III.RESULTS 11 IV.DISCUSSION 14 V.CONCLUSION 17 VI.REFERENCES 18 VII.국문요약 20MasterPeriodontal diseases and dental diseases are proved as a ...
홍윤표
core  

Teriparatide as treatment of the Medication Related Osteonecrosis of the Jaws (MRONJ): a Scoping Review: TREATMENT OF MRONJ USING TERIPARATIDE

Introduction: Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication affecting patients undergoing therapy with bisphosphonates and other antiresorptive agents.
Bustos Ponce, Alexis Paolo, Dethlefs Canto, Jessika, Hurtado Almonacid, Montserrat, Villavicencio Duarte, Javier, Baeza Vallejos, Solange, Pérez Escobari, Javiera   +5 more
core   +1 more source

Osteoclast profile of medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy: a comparison with osteoradionecrosis and osteomyelitis

Journal of Translational Medicine, 2017
Background The medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy [MRONJ (BP)] is characterized by non-healing exposed bone in the maxillofacial region. The pathogenesis of MRONJ (BP) is not fully understood.
Christian Gross, Manuel Weber, Kay Creutzburg, Patrick Möbius, Raimund Preidl, Kerstin Amann, Falk Wehrhan   +6 more
doaj   +1 more source

Inflammation Can Be a High-Risk Factor for Mucosal Nonunion of MRONJ by Regulating SIRT1 Signaling When Treated with an Oncologic Dose of Zoledronate

Drug Design, Development and Therapy
Siqi Zhu,1– 3,* Yajun Cui,2,3,* Weidong Zhang,2,3 Yu Ji,2,3 Lingshuang Li,2,3 Shenglei Luo,4 Jing Cui,5,6 Minqi Li2,3 1School of Stomatology, Jinzhou Medical University, Jinzhou, People’s Republic of China; 2Department of Bone Metabolism, School ...
Zhu S, Cui Y, Zhang W, Ji Y, Li L, Luo S, Cui J, Li M   +7 more
doaj  

New MRONJ guidance [PDF]

British Dental Journal, 2020
openaire   +2 more sources