Results 61 to 70 of about 2,084 (136)

How does medication-related osteonecrosis of the jaw (MRONJ) influence the health-related quality of life after surgery?

BMC Oral Health
Background Medication-Related Osteonecrosis of the Jaw (MRONJ), an established side effect of antiresorptive and antiangiogenic medication, could sometimes require surgical intervention, such as decortication. The objectives of this retrospective patient
Oliver Bissinger, Josefa Greiser, Elisabeth Maier, Philipp Ehrmann, Tamara Kakoschke, Klaus-Dietrich Wolff, Carolin Götz   +6 more
doaj   +1 more source

Imbalance of Serum Bone-Metabolism-Related Factors Associated with Osteonecrosis of the Jaw

Biomedicines
Background: Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse effect of bone-modifying agents. The aim of this study was to elucidate the pathogenesis of MRONJ through a comprehensive comparison of bone-metabolism-related factors ...
Kazuyuki Yusa, Yuji Takeda, Nobuyuki Sasahara, Tomoharu Hemmi, Shigeo Ishikawa, Tsuneo Konta   +5 more
doaj   +1 more source

Osteoclast profile of medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy: a comparison with osteoradionecrosis and osteomyelitis

Journal of Translational Medicine, 2017
Background The medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy [MRONJ (BP)] is characterized by non-healing exposed bone in the maxillofacial region. The pathogenesis of MRONJ (BP) is not fully understood.
Christian Gross, Manuel Weber, Kay Creutzburg, Patrick Möbius, Raimund Preidl, Kerstin Amann, Falk Wehrhan   +6 more
doaj   +1 more source

Inflammation Can Be a High-Risk Factor for Mucosal Nonunion of MRONJ by Regulating SIRT1 Signaling When Treated with an Oncologic Dose of Zoledronate

Drug Design, Development and Therapy
Siqi Zhu,1– 3,* Yajun Cui,2,3,* Weidong Zhang,2,3 Yu Ji,2,3 Lingshuang Li,2,3 Shenglei Luo,4 Jing Cui,5,6 Minqi Li2,3 1School of Stomatology, Jinzhou Medical University, Jinzhou, People’s Republic of China; 2Department of Bone Metabolism, School ...
Zhu S, Cui Y, Zhang W, Ji Y, Li L, Luo S, Cui J, Li M   +7 more
doaj  

Preparing Dental Hygiene Students to Care for Patients With Breast Cancer

Journal of Dental Education, Volume 90, Issue S1, Page S6-S7, June 2026.
Denise M. Messina, Matthew J. Messina
wiley   +1 more source

Survey of Dentists’ Knowledge Regarding Medication-Related Osteonecrosis of the Jaws.

Batna Journal of Medical Sciences
Objective: To evaluate the knowledge of dentists regarding medication-related osteonecrosis of the jaws (MRONJ) in the municipality of Annaba.
Meriem TAGUIA, Razika SALAH MARS
doaj   +1 more source

Case Report: single low-dose of denosumab as a trigger of MRONJ development in a patient with osteoporosis after bisphosphonate therapy

Frontiers in Oral Health
Both denosumab (DMB) and bisphosphonates (BPs), antiresorptive drugs (ARDs) used for the treatment of osteoporosis and oncological disorders, are known for their potential to cause medication-related osteonecrosis of the jaws (MRONJ).
Dávid Száraz, Dávid Száraz, Vojtěch Peřina, Vojtěch Peřina, Jana Treglerová, Jana Treglerová, Ctirad Macháček, Ctirad Macháček, Ondřej Zendulka, Petra Bořilová Linhartová, Petra Bořilová Linhartová   +10 more
doaj   +1 more source

Cumulative incidence and risk factors for medication-related osteonecrosis of the jaw during long-term prostate cancer management

Scientific Reports
Bone-modifying agents (BMA) are extensively used in treating patients with prostate cancer with bone metastases. However, this increases the risk of medication-related osteonecrosis of the jaw (MRONJ).
Masaru Tani, Koji Hatano, Akihiro Yoshimura, Yuki Horibe, Yutong Liu, Nesrine Sassi, Toshiki Oka, Yohei Okuda, Akinaru Yamamoto, Toshihiro Uemura, Gaku Yamamichi, Yu Ishizuya, Yoshiyuki Yamamoto, Taigo Kato, Atsunari Kawashima, Norio Nonomura   +15 more
doaj   +1 more source

Development of a Medication-Related Osteonecrosis of the Jaw Prediction Model Using the FDA Adverse Event Reporting System Database and Machine Learning

Pharmaceuticals
Background: Medication-related osteonecrosis of the jaw (MRONJ) is a rare but serious adverse event. Herein, we conducted a quantitative structure–activity relationship analysis using the U.S.
Shinya Toriumi, Komei Shimokawa, Munehiro Yamamoto, Yoshihiro Uesawa   +3 more
doaj   +1 more source

Comprehensive profiling of plasma and exosomal microRNAs in medication-related osteonecrosis of the jaw

Scientific Reports
The role of circulating microRNAs (miRNAs) in the pathophysiology of medication-related osteonecrosis of the jaw (MRONJ) remains to be elucidated.
Sujin Oh, Minjae Park, Hyun Hwang, Jung-Hyun Park, Keun-Suh Kim, Jin-Woo Kim, Hyo-Jung Lee   +6 more
doaj   +1 more source