Results 41 to 50 of about 2,084 (136)

Medication-related osteonecrosis of the jaw after dental clearance: Prevalence in an oncology center

Saudi Dental Journal, 2022
Objective: Medication-related osteonecrosis of the jaw (MRONJ), a complication of bisphosphonate therapy, has significant morbidity. This study aimed to determine the prevalence of MRONJ and compare its risks among patients who received antiresorptive or
Saad Hajeri, BDS, Yasir Alturkistany, BDS, MBA   +1 more
doaj   +1 more source

New Insights Into Diffuse Sclerosing Osteomyelitis: Is There a Role of ANA and Vitamin B6?

Oral Diseases, EarlyView.
ABSTRACT Object Diffuse sclerosing osteomyelitis is a poorly understood chronic disease, which appears predominantly in the mandible. Female patients are more often affected than men. DSO is an ultra‐rare disease and incidence is unknown; diagnosis can be very challenging; pathogenesis is poorly understood.
Katharina Theresa Obermeier, Tim Hildebrandt, Ina Dewenter, Wenko Smolka, Eric Hesse, Philipp Poxleitner, Sven Otto   +6 more
wiley   +1 more source

Radiographic Analysis of MRONJ in Osteoporotic and Oncologic Patients on Bisphosphonates or Denosumab

Oral Diseases, EarlyView.
ABSTRACT Introduction Medication‐Related Osteonecrosis of the Jaw (MRONJ) is a severe adverse effect of antiresorptive and antiangiogenic treatment, primarily in osteoporotic and oncologic patients. The disease is characterized by persistent jawbone necrosis that results in significant impairment of the quality of life of involved patients.
Omar Ghanaiem, Gavriel Chaushu, Daya Masri   +2 more
wiley   +1 more source

Dentists' knowledge about medication-related osteonecrosis of the jaw and its management

Heliyon, 2020
Objectives: To assess the knowledge of dentists regarding medication-related osteonecrosis of the jaw (MRONJ). Methods: In this cross-sectional study, 74 dentists from governmental hospitals in Riyadh (Dental University Hospital in King Saud University ...
R. Al-Eid, T. Alduwayan, M. Bin Khuthaylah, M. Al Shemali   +3 more
doaj   +1 more source

The Role of the Mylohyoid Line in the Spread of Mandibular Odontogenic Deep Neck Infection

Oral Diseases, EarlyView.
ABSTRACT Introduction Although mandibular odontogenic deep neck infections are occasionally fatal, the transmission pathway has not been elucidated. Materials and Methods This multicenter retrospective study was comprised of the patients of both sexes who were over 18 years of age and who had mandibular odontogenic deep neck abscesses.
Eiji Iwata, Kyoichi Obata, Shogo Kikuta, Naoki Kaneko, Kotaro Sato, Norio Kitagawa, Yohei Takeshita, Katsuhisa Matsuo, Junsei Sameshima, Akira Tachibana, Shintaro Kawano, Jingo Kusukawa, Masaya Akashi, Soichiro Ibaragi, Joe Iwanaga   +14 more
wiley   +1 more source

Potential role of comprehensive dental care in preventing medication related osteonecrosis of the jaw (MRONJ): a single centre study

BMC Oral Health
Objective Medication-related osteonecrosis of the jaw bones (MRONJ) is a well-known complication of antiresorptive and antiangiogenic drugs. Since the first report, more occurrences of MRONJ have been described worldwide.
Kamila Alblazi, Syed Nabil, Nor Rafeah Tumian, Siti Salmiah Mohd Yunus, Roszalina Ramli   +4 more
doaj   +1 more source

Is Fluorescence‐Guided Surgery Reliable for the Treatment of MRONJ? A Systematic Review and Meta‐Analysis

Oral Diseases, EarlyView.
ABSTRACT Background Identification of healthy bone margins is a critical step in the surgical resective treatment of medication‐related osteonecrosis of the jaw (MRONJ). Fluorescence‐guided surgery (FGS) has been proposed as a method to identify resection margins and improve clinical outcomes.
Paolo De Angelis, Alessandro Donato Tescione, Ivan Michele Aniceto, Cosimo Rupe, Gioele Gioco, Romeo Patini, Carlo Lajolo   +6 more
wiley   +1 more source

Medication-related osteonecrosis of the jaws: a series of 22 cases highlighting their histopathological features [PDF]

Brazilian Oral Research
This study aimed to assess the clinicopathological characteristics of medication-related osteonecrosis of the jaw (MRONJ), addressing histopathological features and bone structure.
Dandara Andrade de SANTANA, Yann Victor Paiva BASTOS, Paulo Tambasco de OLIVEIRA, Bruno Cunha PIRES, Flávia Caló Aquino XAVIER, Águida Cristina Gomes Henriques LEITÃO, Larissa Abbehusen COUTO, André Sampaio SOUZA, Luciana Maria Pedreira RAMALHO, Patrícia Ramos CURY, Jean Nunes dos SANTOS   +10 more
doaj   +1 more source

Combined Effects of Romosozumab and Zoledronate on the Development of Osteonecrosis of the Jaw

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to assess the occurrence of medication‐related osteonecrosis of the jaw (MRONJ) in mice following the sequential administration of romosozumab and zoledronate and to confirm their inhibitory effects on osteoclast differentiation in vitro.
Hae‐Seo Park, Shihyun Kim, Seo‐Yeong An, Reuben H. Kim, Jongho Choi, Moon‐Young Kim   +5 more
wiley   +1 more source

Oral Health Screening Prior to Oncological Treatment—The Helsinki Protocol

Oral Diseases, EarlyView.
ABSTRACT Objectives Oncological treatments can have adverse effects on oral health and cause long‐term complications such as osteonecrosis. This retrospective study investigated the oral health of head and neck cancer patients before radiotherapy and patients with multiple myeloma, breast, prostate, lung, and kidney cancers before antiresorptive ...
Jemina Järvinen, Johanna Uittamo, Hanna Välimaa, Tero Puolakkainen, Aleksi Haapanen   +4 more
wiley   +1 more source