Results 31 to 40 of about 4,080 (215)

Risk factors for the development of medication-related osteonecrosis of the jaw and effects of tooth extraction with local infection

Journal of Dental Sciences
Background/purpose: Tooth extraction has been avoided in patients receiving antiresorptive agent (ARA) therapy. This study aimed to investigate dental findings associated with medication-related osteonecrosis of the jaw (MRONJ) development in patients ...
Norio Nakamura, Mitsunobu Otsuru, Taro Miyoshi, Koki Suyama, Keisuke Omori, Kota Morishita, Sakiko Soutome, Satoshi Rokutanda, Kei-ichiro Miura, Masahiro Umeda   +9 more
doaj   +1 more source

Prevention and treatment of oral adverse effects of antiresorptive medications for osteoporosis – A position paper of the Brazilian Society of Endocrinology and Metabolism (SBEM), Brazilian Society of Stomatology and Oral Pathology (Sobep), and Brazilian Association for Bone Evaluation and Osteometabolism (Abrasso)

Archives of Endocrinology and Metabolism, 2020
Antiresorptive therapy is the main form of prevention of osteoporotic or fragility fractures. Medication-related osteonecrosis of the jaw (MRONJ) is a relatively rare but severe adverse reaction to antiresorptive and antiangiogenic drugs.
Miguel Madeira, André Caroli Rocha, Carolina Aguiar Moreira, Águida Maria Menezes Aguiar, Sergio Setsuo Maeda, Abel Silveira Cardoso, Charlles Heldan de Moura Castro, Catarina Brasil D'Alva, Barbara Campolina Carvalho Silva, Bruno Ferraz-de-Souza, Marise Lazaretti-Castro, Francisco Bandeira, Sandra R. Torres   +12 more
doaj   +1 more source

Outcomes and Limitations of Conservative treatment and Timing of Switching to Surgical Treatment for Medication-Related Osteonecrosis of the Jaw [PDF]

, 2021
薬剤関連顎骨壊死（以下，MRONJ）の治療では積極的に外科療法を推奨する報告が多くみられる一方，保存療法に関して有効性や治療成績を示した報告は少ない．われわれはMRONJ治療の現状について臨床統計学的に解析し，保存療法の治療効果と限界および外科療法への切り替え時期について検討を行った． 対象は，2008年から2020年までに当科で治療を行ったMRONJ患者157例（男性44例，女性113例，平均年齢74歳）とした． 　保存療法と外科療法の治療効果比較では，保存療法の有効率（61.7％），治癒率（38.3％
川又, 均, 和久井, 崇大, Kamimura, Ryouta, Wakui, Takahiro, 大島, 遼, Sawatani, Yuta, 上村, 亮太, 藤田, 温志, Izumi, Sayaka, 俵藤, 俊暉, Kawamata, Hitoshi, Fukumoto, Chonji, 澤谷, 祐大, Hasegawa, Tomonori, 長谷川, 智則, 福本, 正知, Oshima, Ryo, Fujita, Atsushi, 泉, さや香, Hyodo, Toshiki   +19 more
core  

Human amniotic membrane in the treatment of MRONJ [PDF]

, 2021
PURPOSE Human amniotic membrane (HAM) has biological properties which are important for the experimental and clinical applications in managing patients of various medical specialties such as oral and maxilla-facial surgery. The aim was to evaluate the use of HAM as improvement in surgical wound healing and reduction of relapse in patient affected by ...
Matteo Val, Diletta Trojan, Luca Guarda Nardini, Francesca Favaretto, Mirko Ragazzo   +4 more
openaire   +2 more sources

Medication-Related Osteonecrosis of Jaws (MRONJ) Prevention and Diagnosis: Italian Consensus Update 2020 [PDF]

, 2020
The Medication-Related Osteonecrosis of Jaws (MRONJ) diagnosis process and its prevention play a role of great and rising importance, not only on the Quality of Life (QoL) of patients, but also on the decision-making process by the majority of dentists ...
Bedogni A., Vittorio Fusco, Meleti M., Colella G., Santarelli A., Antonio Lo Casto, Mignogna M. D., Gabriele, Mario, Panzarella V, Santarelli A, giuseppina campisi, Biasotto M., Vescovi P., Favia G, Vescovi P, Marchetti C., Favia, Gianfranco, Campisi, Giuseppina, Mario Gabriele, Di Fede, Olga, Fusco V, Mignogna, Michele D, Consolo U., Campisi G., Mauceri, Rodolfo, Ugo Consolo, olga di fede, Biasotto M, Favia G., Di Fede O, Panzarella, Vera, Oteri, Giacomo, Consolo U, Meleti M, Gabriele M, Prof. Lorenzo Lo Muzio, Campisi G, Lo Muzio, Lorenzo, Marco Mascitti, Claudio Marchetti, Andrea Santarelli, Gabriele M., Vera Panzarella, Fusco V., Marcianò A, Giacomo Oteri, Marchetti, Claudio, Romeo U., Colella G, Bertoldo, Francesco, Biasotto, Matteo, Bedogni, Alberto, Mignogna MD, Marco Meleti, Marciano A., Oteri G., Marchetti C, Colella, Giuseppe, Santarelli, Andrea, Bettini G., Lo Casto A., Alberto Bedogni, Lorenzo Lo Muzio, Romeo U, Antonia Marcianò, Mauceri R, Rodolfo Mauceri, Oteri G, Mascitti M., Bertoldo F., Michele D. Mignogna, Bertoldo F, Giordana Bettini, Mauceri R., Lo Casto A, Gianfranco Favia, Lo Muzio L, Paolo Vescovi, Matteo Biasotto, Mascitti M, Marcianò, Antonia, Lo Muzio L., Di Fede O., Mascitti, Marco, Bettini G, Francesco BERTOLDO, Consolo, Ugo, Panzarella V., Vescovi, Paolo, Giuseppe Colella, Meleti, Marco, umberto romeo, Bettini, Giordana, Romeo, Umberto, Fusco, Vittorio, Lo Casto, Antonio   +95 more
core   +1 more source

Medication-related osteonecrosis of the jaw without osteolysis on computed tomography: a retrospective and observational study

Scientific Reports, 2023
Medication-related osteonecrosis of the jaw (MRONJ) is a refractory osteonecrosis caused by antiresorptive agents such as bisphosphonate and denosumab (DMB).
Yuki Sakamoto, Shunsuke Sawada, Yuka Kojima   +2 more
doaj   +1 more source

Local delivery of VEGF-Hydrogel in developing MRONJ lesion modulates socket healing and systemic cytokine response

, 2017
Objectives: Aetiopathogenesis of medication-related osteonecrosis of the jaw (MRONJ)was classically considered to involve direct suppression of osteoclast-induced boneremodelling and cytotoxic effects of Zoledronic acid (ZA).
Sharma, Chakrabhavi Gundurao Dileep, Hamlet, Stephen, Ivanovski, Saso   +2 more
core   +2 more sources

Medication Related Osteonecrosis of the Jaw: Knowledge, Attitudes and Practice Patterns Among Australian Dental Practitioners

Australian Dental Journal, EarlyView.
ABSTRACT Background Medication related osteonecrosis of the jaw (MRONJ) is a debilitating condition associated with antiresorptive and antiangiogenic therapies. As the use of these medications continues to increase, dental practitioners play a critical role in prevention and management of at‐risk patients. This survey evaluated the awareness, knowledge
Ying Shi Chang, Christopher Friel, Gary Low, Albert Yaacoub, Stephen Clive Cox   +4 more
wiley   +1 more source

Case series of medication-related osteonecrosis of the jaw (MRONJ) patients prescribed a drug holiday

, 2023
The role of a drug holiday in the management of medication-related osteonecrosis of the jaw (MRONJ) remains controversial. Current UK guidance does not recommend this practice given the lack of conclusive evidence, and potential risk of skeletal-related ...
Gormley, Mark, Hamid, Aruche, Bell, Christopher, Thomas, Steve J   +3 more
core   +1 more source

The Effects of Simulation‐Based Interprofessional Education on Oncology Oral Care Competencies Among Dental and Dental Hygiene Students

European Journal of Dental Education, EarlyView.
ABSTRACT Introduction This study applied simulation‐based interprofessional education (IPE) principles to develop an oncology oral care scenario, with the aim of evaluating the intervention's effects on the IPE core competencies of dental and dental hygiene students before their clinical internships. Materials and Methods Twenty‐eight fifth‐year dental
Shin‐Ru Liao, Pei‐Chen Lin, Ai‐Hua Chang, Kun‐Tsung Lee, Peih‐Ying Lu, Hsiao‐Ling Huang, Ju‐Hui Wu   +6 more
wiley   +1 more source