Results 21 to 30 of about 4,080 (215)

Clinical values of serum Semaphorin 4D (Sema4D) in medication‑related osteonecrosis of the jaw

European Journal of Medical Research, 2023
Background Bisphosphonates (BPs) are widely used in clinical practice to prevent and treat bone metabolism-related diseases. Medication-related osteonecrosis of the jaw (MRONJ) is one of the major sequelae of BPs use. Early prediction and intervention of
Hong Mu, Ying Pang, Lili Liu, Jingbo Liu, Chunsheng Liu   +4 more
doaj   +1 more source

Osteoporosis Management after the Occurrence of Medication-Related Osteonecrosis of the Jaw: A 13-Year Experience at a Tertiary Center [PDF]

Endocrinology and Metabolism
Background We investigated osteoporosis management strategies and clinical outcomes following the occurrence of medicationrelated osteonecrosis of the jaw (MRONJ).
Chun Ho Wong, Kimberly Hang Tsoi, Jingya Jane Pu, Nancy Su Jiang, Stacey Sheung Yi Chan, Connie Hong Nin Loong, Xincheng Zou, Carol Ho Yi Fong, Eunice Ka Hong Leung, Alan Chun Hong Lee, Chi Ho Lee, Kathryn Choon Beng Tan, Yu Cho Woo, Yu-xiong Su, David Tak Wai Lui   +14 more
doaj   +1 more source

MRONJ in breast cancer patients under bone modifying agents for cancer treatment-induced bone loss (CTIBL): a multi-hospital-based case series

BMC Oral Health, 2023
Background Cancer treatment-induced bone loss (CTIBL) is the most common adverse event experienced by patients affected by breast cancer (BC) patients, without bone metastases.
Rodolfo Mauceri, Martina Coppini, Massimo Attanasio, Alberto Bedogni, Giordana Bettini, Vittorio Fusco, Amerigo Giudice, Filippo Graziani, Antonia Marcianò, Marco Nisi, Gaetano Isola, Rosalia Maria Leonardi, Giacomo Oteri, Corrado Toro, Giuseppina Campisi   +14 more
doaj   +1 more source

Role of preoperative SPECT/CT standardized uptake values in medication-related osteonecrosis of the jaw: a preliminary study of SPECT/CT in relation to cone-beam CT and histopathological findings of the resected bone of mandibulectomy

The Egyptian Journal of Radiology and Nuclear Medicine, 2023
Background SPECT/CT has been applied for preoperative planning of MRONJ. Furthermore, the SUV using bone SPECT/CT has enabled quantitative analysis of jaw lesions.
Eizaburo Kobayashi, Yasuhito Tezuka, Junya Ono, Yasuo Okada, Ichiro Ogura   +4 more
doaj   +1 more source

Medication-Related Osteonecrosis of the Jaw Spontaneously Occurred in a Patient with Chronic Myelogenous Leukemia Only by Imatinib: A Report of a Rare Case

Case Reports in Dentistry, 2021
The prevalence of medication-related osteonecrosis of the jaw (MRONJ) associated with molecular-targeted therapies such as bevacizumab and sunitinib has been constantly increasing in recent years.
Makiko Okubo-Sato, Kenji Yamagata, Satoshi Fukuzawa, Kazuhiro Terada, Fumihiko Uchida, Naomi Ishibashi-Kanno, Hiroki Bukawa   +6 more
doaj   +1 more source

Artificial Intelligence-Driven Precision Bisphosphonate Therapy in Osteoporosis: Mechanisms, Clinical Applications, Risks, and Future Directions. [PDF]

Orthop Surg
This comprehensive review integrates 17 benchmark studies to illustrate the transition of osteoporosis management toward precision medicine. The schematic highlights three key clinical applications: AI‐driven opportunistic screening from routine CTs, precision pharmacotherapy selection, and the predictive prevention of adverse events like MRONJ ...
Yao X, Chao Y, Gu X, Peng J, Yuan J, Shi W, Zhang F, Bao Q.   +7 more
europepmc   +2 more sources

Goodbye BRONJ… Hello MRONJ [PDF]

CRANIO®, 2016
Since the first reports in 2003 and 2004, osteonecrosis of the jaws (ONJ), associated with the bisphosphonate drugs used in the treatment of certain malignancies, and osteoporosis have been a promi...
openaire   +2 more sources

MRONJ approach of medical doctors who prescribing antiresorptive drug [PDF]

, 2021
Amaç: Diş çekimi gibi çene üzerinde cerrahi işlem uygulandığında, kemik iyileşmesinin bozulmasıyla çenenin bifosfonat ilişkili nekrozu meydana gelebilir.
Koçyiğit, Hayrunisa, Şenol, Gamze, Süzen, Muazzez, Güldiken, İpek Necla, Delilbaşı, Çağrı   +4 more
core   +1 more source

Metabolomic profiling reveals salivary hypotaurine as a potential early detection marker for medication-related osteonecrosis of the jaw.

PLoS ONE, 2019
Medication-related osteonecrosis of the jaw (MRONJ) is a rare but serious adverse event of bone-modifying agents used to prevent bone complications in cancer patients with bone metastasis.
Wakako Yatsuoka, Takao Ueno, Kanako Miyano, Yasuhito Uezono, Ayame Enomoto, Miku Kaneko, Sana Ota, Tomoyoshi Soga, Masahiro Sugimoto, Toshikazu Ushijima   +9 more
doaj   +1 more source

A retrospective study on odontogenic and non-odontogenic medication-related osteonecrosis of the jaw: Potential differences in clinical features and treatment outcomes

Journal of Dental Sciences
Background/purpose: Local infections, such as periodontal disease or apical lesions, and invasive dental procedures, such as tooth extraction, are thought to trigger medication-related osteonecrosis of the jaw (MRONJ) development.
Mizuho Ohnuma, Mitsunobu Otsuru, Keisuke Omori, Kota Morishita, Saki Hayashida, Sakiko Soutome, Kei-ichiro Miura, Masahiro Umeda, Tomohiro Yamada   +8 more
doaj   +1 more source