Two novel mutations in MSX1 causing oligodontia.
PLoS ONE, 2020 Tooth agenesis is one of the most common developmental anomalies in humans and can affect dental occlusion and speech pronunciation. Research has identified an association between mutations in MSX1, PAX9, EDA, AXIN2, WNT10A, WNT10B and LRP6 and human ...
Le Yang +3 more
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In silico characterization and structural modeling of a homeobox protein MSX1 from Homo sapiens
Informatics in Medicine Unlocked, 2021 Introduction: MSX1 protein, a homeobox transcriptional regulator plays a significant role in various developmental processes of the mammalian system such as limb-pattern formation, craniofacial development, in particular, odontogenesis, and tumor growth ...
Tp Chaturvedi +2 more
exaly +3 more sources
The regenerative plasticity of isolated urodele myofibers and its dependence on MSX1. [PDF]
PLoS Biology, 2004 The conversion of multinucleate postmitotic muscle fibers to dividing mononucleate progeny cells (cellularisation) occurs during limb regeneration in salamanders, but the cellular events and molecular regulation underlying this remarkable process are not
Anoop Kumar +3 more
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Novel MSX1 variants identified in families with nonsyndromic oligodontia [PDF]
International Journal of Oral Science, 2021 The goal of this study was to identify MSX1 gene variants in multiple Chinese families with nonsyndromic oligodontia and analyse the functional influence of these variants. Whole-exome sequencing (WES) and Sanger sequencing were performed to identify the
Jinglei Zheng +6 more
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Association of MSX1 gene polymorphisms and maxillary lateral incisor agenesis in Non-syndromic cleft lip and/or palate individuals [PDF]
Journal of Oral Biology and Craniofacial ResearchBackground: To investigate the association between MSX1 gene polymorphisms and maxillary lateral incisor agenesis with and without Non Syndromic Cleft lip and palate (NSCL/P) in a South Indian population.
Dhanyashri Kamalakannan +4 more
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Association between PAX9 or MSX1 gene polymorphism and tooth agenesis risk: A meta-analysis [PDF]
Open Life SciencesZhong Xiaoyi +4 more
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Cells, 2021 Pulmonary arterial hypertension (PAH) is a progressive lung disease caused by thickening of the pulmonary arterial wall and luminal obliteration of the small peripheral arteries leading to increase in vascular resistance which elevates pulmonary artery ...
James West +5 more
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Correction to "The Activation of cGAS-STING Pathway Causes Abnormal Uterine Receptivity in Aged Mice". [PDF]
Aging CellAging Cell, Volume 25, Issue 5, May 2026.
europepmc +2 more sources
Dedifferentiation of Mammalian Myotubes Induced by msx1 [PDF]
Cell, 2000 The process of cellular differentiation culminating in terminally differentiated mammalian cells is thought to be irreversible. Here, we present evidence that terminally differentiated murine myotubes can be induced to dedifferentiate. Ectopic expression of msx1 in C2C12 myotubes reduced the nuclear muscle proteins MyoD, myogenin, MRF4, and p21 to ...
Odelberg, Shannon J. +2 more
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Generation of a MSX1 knockout human embryonic stem cell line using CRISPR/Cas9 technology
Stem Cell Research, 2022 The MSX1 gene encodes a transcriptional repressor and plays important roles in limb-pattern formation, craniofacial development, and odontogenesis during vertebrate embryogenesis.
Weicheng Chiu +4 more
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