Results 11 to 20 of about 6,450 (193)
The regenerative plasticity of isolated urodele myofibers and its dependence on MSX1. [PDF]
PLoS Biology, 2004 The conversion of multinucleate postmitotic muscle fibers to dividing mononucleate progeny cells (cellularisation) occurs during limb regeneration in salamanders, but the cellular events and molecular regulation underlying this remarkable process are not
Anoop Kumar +3 more
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Two novel mutations in MSX1 causing oligodontia.
PLoS ONE, 2020 Tooth agenesis is one of the most common developmental anomalies in humans and can affect dental occlusion and speech pronunciation. Research has identified an association between mutations in MSX1, PAX9, EDA, AXIN2, WNT10A, WNT10B and LRP6 and human ...
Le Yang +3 more
doaj +5 more sources
Emerin anchors Msx1 and its protein partners at the nuclear periphery to inhibit myogenesis
Cell & Bioscience, 2019 Background Previous studies have shown that in myogenic precursors, the homeoprotein Msx1 and its protein partners, histone methyltransferases and repressive histone marks, tend to be enriched on target myogenic regulatory genes at the nuclear periphery.
Zhangjing Ma +8 more
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A Nonsense Mutation in MSX1 Causes Witkop Syndrome [PDF]
The American Journal of Human Genetics, 2001 Witkop syndrome, also known as tooth and nail syndrome (TNS), is a rare autosomal dominant disorder. Affected individuals have nail dysplasia and several congenitally missing teeth. To identify the gene responsible for TNS, we used candidate-gene linkage analysis in a three-generation family affected by the disorder.
Jumlongras, Dolrudee +9 more
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Transcriptional Regulation of Msx1 Natural Antisense Transcript
Cells Tissues Organs, 2011 Msx homeogenes play an important role in the epithelial-mesenchymal interactions leading development. Msx1 is relevant for dental and craniofacial morphogenesis, as suggested by phenotypes of Msx1 mutations in human and Msx1 KO mice. Our group showed that Msx1 gene expression can be regulated by a bidirectional transcription generating long noncoding ...
Sylvie, Babajko +4 more
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Cells, 2021 Pulmonary arterial hypertension (PAH) is a progressive lung disease caused by thickening of the pulmonary arterial wall and luminal obliteration of the small peripheral arteries leading to increase in vascular resistance which elevates pulmonary artery ...
James West +5 more
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A novel MSX1 mutation in hypodontia
American Journal of Medical Genetics Part A, 2004 AbstractMSX1 mutations have been reported in four unrelated families with autosomal dominant tooth agenesis. In one family, some individuals also had cleft lip and/or palate. We have identified a novel MSX1 mutation (559 C → T, resulting in Gln187Stop) in three individuals of one family. © 2004 Wiley‐Liss, Inc.
S, De Muynck +5 more
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Msx1 and Msx2 promote meiosis initiation
Development, 2011 The mechanisms regulating germ line sex determination and meiosis initiation are poorly understood. Here, we provide evidence for the involvement of homeobox Msx transcription factors in foetal meiosis initiation in mammalian germ cells. Upon meiosis initiation, Msx1 and Msx2 genes are strongly expressed in the foetal ovary, possibly stimulated by ...
Le Bouffant, Ronan +8 more
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Wnt/β-catenin signaling and Msx1 promote outgrowth of the maxillary prominences
Frontiers in Physiology, 2012 Facial morphogenesis requires a series of precisely orchestrated molecular events to promote the growth and fusion of the facial prominences. Cleft palate (CP) results from perturbations in this process.
Marie eMedio +6 more
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Unlocking predictive genetic factors with artificial intelligence: relationship between dental impaction and hypodontia evaluated via association-rule algorithms: a case–control study [PDF]
Saudi Dental JournalArtificial intelligence (AI)-driven genetic analysis is crucial for the advancement of personalized dental treatments. Despite progress in genetic research, its clinical application remains limited.
Nora Alhazmi +7 more
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