Results 101 to 110 of about 156,870 (288)

Phylogenetic relatedness of Erebia medusa and E. epipsodea (Lepidoptera: Nymphalidae) confirmed

European Journal of Entomology, 2013
The extensive genus Erebia is divided into several groups of species according to phylogenetic relatedness. The species Erebia medusa was assigned to the medusa group and E. epipsodea to the alberganus group.
Martina ŠEMELÁKOVÁ, Peter PRISTAŠ, Ľubomír PANIGAJ   +2 more
doaj   +1 more source

Digital PCR methods improve detection sensitivity and measurement precision of low abundance mtDNA deletions [PDF]

, 2016
Mitochondrial DNA (mtDNA) mutations are a common cause of primary mitochondrial disorders, and have also been implicated in a broad collection of conditions, including aging, neurodegeneration, and cancer.
A Bender, C Barthélémy, CT Moraes, CT Moraes, DC Wallace, DW Dong, Ea Schon, EJ Brierley, G Campbell, J Damas, J Damas, J Villarroya, J Wanagat, JB Stewart, JP Grady, K Khrapko, K Maniura-Weber, KJ Krishnan, L He, L Van Haute, L-JJC Wong, LC Greaves, M Elstner, M Sciacco, NF Cariello, NG Gokey, NR Phillips, NZ Lax, P Manoj, PF Chinnery, RW Taylor, S DiMauro, SD Taylor, SSL Chan, V Nesbitt, X Guo, Y Kraytsberg, Y Tang, Z Cao   +38 more
core   +1 more source

Play Around with mtDNA [PDF]

DNA and Cell Biology, 2020
Cali T., Brini M.
openaire   +2 more sources

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

Evolutionary associations between sand seatrout (Cynoscion arenarius) and silver seatrout (C. nothus) inferred from morphological characters, mitochondrial DNA, and microsatellite markers [PDF]

, 2009
The evolutionary associations between closely related fish species, both contemporary and historical, are frequently assessed by using molecular markers, such as microsatellites.
Anderson, Joel D., Karel, William J., McDonald, Dusty L., Sutton, Glen R.   +3 more
core  

Mitochondrial TERT enhances mitochondria functions in vivo by protecting mitochondrial DNA integrity from oxidative damage : meeting abstract [PDF]

, 2009
Mitochondria are essential for respiration and oxidative phosphorylation. Mitochondrial dysfunction due to aging processes is involved in pathologies and pathogenesis of a series of cardiovascular disorders. New results accumulate showing that the enzyme
Altschmied, Joachim, Brandt, Ulrich, Büchner, Nicole, Dröse, Stefan, Haendeler, Judith, Jakob, Sascha   +5 more
core   +1 more source

Repeated Disuse Atrophy Imprints a Molecular Memory in Skeletal Muscle: Transcriptional Resilience in Young Adults and Susceptibility in Aged Muscle

Advanced Science, EarlyView.
Repeated disuse imprints a molecular memory in skeletal muscle, conferring transcriptional resilience in young adults but exaggerated susceptibility in aged muscle, driven by epigenetic regulation of aerobic metabolism, mitochondrial and NAD+ pathways.
Daniel C. Turner, Truls Raastad, Max Ullrich, Stian F. Christiansen, Hazel Sutherland, James Boot, Eva Wozniak, Charles Mein, Emilie Dalbram, Jonas T. Treebak, Daniel J. Owens, David C. Hughes, Sue C. Bodine, Jonathan C. Jarvis, Adam P. Sharples   +14 more
wiley   +1 more source

Genetic Relationship amongst Marica, Kacang Goat and Capra species

International Journal of Agriculture System, 2015
Marica goat is an endemic species that can be found only in South Sulawesi, Indonesia. It has been reported by the FAO as endangered species because its number of population has been significantly decreased. Domestication by local people has been done by
Rosdiana Ngitung, Herry Sonjaya, Syamsuddin Hasan, Wempie Wempie   +3 more
doaj   +1 more source

Organellar inheritance in the green lineage: insights from Ostreococcus tauri [PDF]

, 2013
Along the green lineage (Chlorophyta and Streptophyta), mitochondria and chloroplast are mainly uniparentally transmitted and their evolution is thus clonal. The mode of organellar inheritance in their ancestor is less certain.
Adam Eyre-Walker, Baur, Birky, Bonen, Boynton, Bruen, Correns, De Clerck, Derelle, Duret, Grimsley, Guindon, Gwenael Piganeau, Hasegawa, Hill, Hill, Houliston, Hua, Huang, Hurst, Hutson, Jancek, Kurtz, Larkin, Lewis, Lewontin, Li, MacAlpine, Marin, Marshall, Maréchal, Maynard Smith, McVean, Miyamura, Muller, Nei, Ness, Olson, Piganeau, Posada, Posada, R Development Core Team, Robbens, Rodríguez-Ezpeleta, Romain Blanc-Mathieu, Sager, Sager, Sager, Simpson, Sophie Sanchez-Ferandin, Städler, Sun, Sung, Swofford, Tamura, Tamura, Tsai   +56 more
core   +1 more source

Dual Covalent Targeting of STING Cysteines 292/309 Disrupts Functional Oligomerization and Enables Potent Antagonist Development

Advanced Science, EarlyView.
We report a rational design strategy for STING antagonists by dual covalent targeting of Cys292/309 in its C‐terminal domain, directly preventing functional oligomerization. Through covalent warhead repurposing, we identified P005091 and revealed its unique dual‐cysteine mechanism.
Yuxuan Zhao, Ling Huang, Wenjing Qin, Bin Zhang, Yang Yang, Xue Chen, Xiaoquan Wang, Weilin Zhou, Feiyang Chen, Zhenyu Li, Liyuan Le, Yiqiu Zhang, Zhen Xiang, Lu Zhang, Fei Wang, Dan Lei, Zi‐zhe Cai, Ying Gao, Yong Chen, Xuecen Wang, Junmin Quan, Shuixing Zhang, Xianzhang Bu, Xin Yue   +23 more
wiley   +1 more source