Results 241 to 250 of about 400,251 (340)

Emerging Nanotechnology Strategies for Obesity Therapy

Advanced Science, EarlyView.
Three types of nanomaterials used for obesity treatment are highlighted, including inorganic nanomaterials, organic nanomaterials and biomimetic nanomaterials. A detailed and comprehensive introduction to the recent nanotechnology strategies for obesity management is also provided, including drug delivery, photodynamic therapy, hyperthermia, gas ...
Weili Chang, Zhaoxu Meng, Yuezhu Zhao, Yake Qi, Zhou Li, He Lian   +5 more
wiley   +1 more source

Targeting the complement-mTOR-autophagy axis: the role of apolipoprotein E in depression. [PDF]

BMC Biol
Li Y, Xu C, Liu J, Guo M, Wang J, Bai X, Cheng Y, Luan X, Pei H, Zhang C, Liu H, Chen M, Tang B.   +12 more
europepmc   +1 more source

Combination of the mTOR inhibitor rapamycin and CC-5013 has synergistic activity in multiple myeloma [PDF]

, 2004
Noopur Raje, Shaji Kumar, Teru Hideshima, Kenji Ishitsuka, Dharminder Chauhan, Constantine S. Mitsiades, Klaus Podar, Steven Le Gouill, Paul G. Richardson, Nikhil C. Munshi, David Stirling, Joseph H. Antin, Kenneth C. Anderson   +12 more
openalex   +1 more source

Rapamycin prevents cerebral stroke by modulating apoptosis and autophagy in penumbra in rats [PDF]

, 2018
Bové, Calastretti, Carloni, Castedo, Castedo, Chauhan, Chen, Chong, Chong, Donnan, Ferri, Flynn, Fu, Genova, Harada, Hwang, Hwang, Jiang, Kofman, Koh, Li, Li, Lu, Lu, Maiese, Rieker, Sanghera, Santini, Schmued, Shahjouei, Siddiqui, Thyrell, Urbanek, Wang, Wang, Wechsler, Wong, Xie, Xie, Yang, Yin, Zare, Zeng   +42 more
core   +2 more sources

RSPO2 Coordinates with GDF9:BMP15 Heterodimers to Promote Granulosa Cell and Oocyte Development in Mice

Advanced Science, EarlyView.
RSPO2 and GDF9:BMP15 heterodimers—core components of oocyte‐secreted factors (OSFs)—coordinate to shape the molecular architecture of preantral granulosa cells via gene‐specific synergistic and antagonistic regulation, mediated through CTNNB1–SMAD2 signaling crosstalk.
Yingmei Wang, Hongjiang Li, Liji You, Shuhui Wang, Jinglei Bie, Ziyang Su, Lanying Shi, You‐Qiang Su   +7 more
wiley   +1 more source

TSC2-mutated perivascular epithelioid cell tumor with partial response to mTOR inhibition: a case report and literature review. [PDF]

Discov Oncol
Suo X, Dong R, Zhang L, Zhang X, Li X, Xiao M.   +5 more
europepmc   +1 more source

Regulation of B-Raf Kinase Activity by Tuberin and Rheb Is Mammalian Target of Rapamycin (mTOR)-independent [PDF]

, 2004
Magdalena Karbowniczek, Timothy P. Cash, Mitchell Cheung, Gavin P. Robertson, Aristotelis Astrinidis, Elizabeth P. Henske   +5 more
openalex   +1 more source

Leptin and mTor [PDF]

Nature Immunology, 2012
openaire   +1 more source

Dopamine D1 Receptor Contributes to Glucocorticoid‐Associated Osteonecrosis of Femoral Head Protection Through the ATF3/CHOP Axis to Inhibit Osteoblastic Apoptosis

Advanced Science, EarlyView.
This work identifies a novel mechanism by which dopamine D1 receptor (DRD1) contributes to the pathogenesis of glucocorticoid (GC)‐associated osteonecrosis of the femoral head (ONFH) through the regulation of osteoblastic apoptosis, indicating that DRD1 serves as a critical mediator of the crosstalk between the nervous and skeletal systems.
Kai Zheng, Wenming Li, Tianhao Wang, Gaoran Ge, Wei Zhang, Yi Qin, Wenhao Li, Zebin Wu, Zhen Wang, Gang Rui, Yaozeng Xu, Dechun Geng   +11 more
wiley   +1 more source

Sexual dimorphism in response to intermittent fasting and its impact on the brain. [PDF]

Sci Rep
Sudasinghe KH, White ZJ, Hall SE.
europepmc   +1 more source