Results 11 to 20 of about 122,305,211 (281)

Estrogen-Regulated Proline-Rich Acidic Protein 1 in Endometrial Epithelial Cells Affects Embryo Implantation by Regulating Mucin 1 in Mice [PDF]

open access: yesBiomolecules
This study explores the regulatory role of proline-rich acidic protein 1 (Prap1) effects on embryo implantation. A high estrogen model and ovariectomized mice were employed to demonstrate that estrogen regulates Prap1 expression.
Xueyan Wang   +5 more
doaj   +2 more sources

Expression of Mucins in Different Entities of Salivary Gland Cancer: Highest Expression of Mucin-1 in Salivary Duct Carcinoma [PDF]

open access: yesHead and Neck Pathology, 2022
AbstractTherapeutic options for advanced salivary gland cancer (SGC) are rare. Therefore, it was the aim of this study to investigate the extent and intensity of Mucin-1 (MUC1), Mucin-16 (MUC16), and Mucin-5AC (MUC5AC) as potential molecular targets using immunohistochemistry.
P. Wolber   +6 more
openaire   +3 more sources

Serum Mucin‐1 (CA15‐3) in Relation to Pulse Pressure Amplification in Untreated Chinese Patients [PDF]

open access: yesThe Journal of Clinical Hypertension
Mucin‐1 was reported be correlated with organ fibrosis. Pulse pressure amplification (PPA) was a marker of arterial stiffness. We investigate the association of serum mucin‐1 (CA15‐3) concentration with peripheral and central blood pressure and PPA in ...
Wen‐Hui Zhai   +10 more
doaj   +2 more sources

MUCIN 1 in Prostate Cancer

open access: yes, 2021
ABSTRACT Despite extensive research efforts in prostate cancer for the last several decades, the disease remains a leading cause of cancer death in men in the developed world. A typical feature of prostate cancer initiation and progression is the landscape of genetic alterations, which changes the expression patterns of numerous molecules in prostate ...
Anil Kapoor   +5 more
openaire   +3 more sources

Transmembrane Mucin-1 Facilitates Oral Microbial Colonization in Oral Cancer

open access: yesOral
Mucins are a family of heavily glycosylated proteins that form the main organic component of the oral mucosal barrier complex. Transmembrane mucin 1 (tMUC1) is anchored at the superficial epithelial surface to provide a protective function.
Bina Kashyap, Arja M. Kullaa
doaj   +2 more sources

Diagnostic Performance of Galectin-1 and Mucin-1 in Uterine Tumors: A Case–Control Study [PDF]

open access: yesCurrent Issues in Molecular Biology
Background and Objectives: Uterine leiomyomas are common benign tumors, whereas uterine sarcomas are rare but aggressive malignancies. Preoperative differentiation among leiomyoma, smooth muscle tumor of uncertain malignant potential (STUMP), and uterine
Paraskevi Karioti   +9 more
doaj   +2 more sources

Plasma Mucin-1 as a Potential Biomarker for Diabetic Peripheral Neuropathy in Type 2 Diabetes [PDF]

open access: yesBiomolecules
Background: Diabetic peripheral neuropathy (DPN) is a major complication of type 2 diabetes mellitus (T2D) that reduces quality of life and increases the risk of foot ulcers and amputations.
Jae-Hyung Park   +6 more
doaj   +2 more sources

Baseline Blood Levels of Mucin-1 Are Associated with Crucial On-Treatment Adverse Outcomes in Patients with Idiopathic Pulmonary Fibrosis Receiving Antifibrotic Pirfenidone [PDF]

open access: yesBiomedicines
Mucin-1 is a multi-functional glycoprotein expressed by type II alveolocytes and may be detectable in the circulation following pulmonary fibrosis. The prognostic utility of baseline pre-treatment blood levels of mucin-1 in patients with idiopathic ...
Tang-Hsiu Huang   +7 more
doaj   +2 more sources

Mucin-1 and its relation to grade, stage and survival in ovarian carcinoma patients

open access: yesBMC Cancer, 2012
Background Mucin-1 is known to be over-expressed by various human carcinomas and is shed into the circulation where it can be detected in patient’s serum by specific anti-Mucin-1 antibodies, such as the tumour marker assays CA 15–3 and CA 27.29.
Engelstaedter Verena   +11 more
doaj   +2 more sources

Expression of cyclooxygenase‑2 and mucin 1 in colorectal cancer [PDF]

open access: yesMolecular and Clinical Oncology, 2020
In colorectal cancer (CRC), pathological factors that correlate with negative prognosis include, among others, overexpression of cyclooxygenase-2 (COX-2) and abundant expression of mucin 1 (MUC1). COX-2 overexpression may therefore be associated with MUC1 overexpression.
Małgorzata Szlendak   +7 more
openaire   +4 more sources

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