Estrogen-Regulated Proline-Rich Acidic Protein 1 in Endometrial Epithelial Cells Affects Embryo Implantation by Regulating Mucin 1 in Mice [PDF]
This study explores the regulatory role of proline-rich acidic protein 1 (Prap1) effects on embryo implantation. A high estrogen model and ovariectomized mice were employed to demonstrate that estrogen regulates Prap1 expression.
Xueyan Wang +5 more
doaj +2 more sources
Expression of Mucins in Different Entities of Salivary Gland Cancer: Highest Expression of Mucin-1 in Salivary Duct Carcinoma [PDF]
AbstractTherapeutic options for advanced salivary gland cancer (SGC) are rare. Therefore, it was the aim of this study to investigate the extent and intensity of Mucin-1 (MUC1), Mucin-16 (MUC16), and Mucin-5AC (MUC5AC) as potential molecular targets using immunohistochemistry.
P. Wolber +6 more
openaire +3 more sources
Serum Mucin‐1 (CA15‐3) in Relation to Pulse Pressure Amplification in Untreated Chinese Patients [PDF]
Mucin‐1 was reported be correlated with organ fibrosis. Pulse pressure amplification (PPA) was a marker of arterial stiffness. We investigate the association of serum mucin‐1 (CA15‐3) concentration with peripheral and central blood pressure and PPA in ...
Wen‐Hui Zhai +10 more
doaj +2 more sources
ABSTRACT Despite extensive research efforts in prostate cancer for the last several decades, the disease remains a leading cause of cancer death in men in the developed world. A typical feature of prostate cancer initiation and progression is the landscape of genetic alterations, which changes the expression patterns of numerous molecules in prostate ...
Anil Kapoor +5 more
openaire +3 more sources
Transmembrane Mucin-1 Facilitates Oral Microbial Colonization in Oral Cancer
Mucins are a family of heavily glycosylated proteins that form the main organic component of the oral mucosal barrier complex. Transmembrane mucin 1 (tMUC1) is anchored at the superficial epithelial surface to provide a protective function.
Bina Kashyap, Arja M. Kullaa
doaj +2 more sources
Diagnostic Performance of Galectin-1 and Mucin-1 in Uterine Tumors: A Case–Control Study [PDF]
Background and Objectives: Uterine leiomyomas are common benign tumors, whereas uterine sarcomas are rare but aggressive malignancies. Preoperative differentiation among leiomyoma, smooth muscle tumor of uncertain malignant potential (STUMP), and uterine
Paraskevi Karioti +9 more
doaj +2 more sources
Plasma Mucin-1 as a Potential Biomarker for Diabetic Peripheral Neuropathy in Type 2 Diabetes [PDF]
Background: Diabetic peripheral neuropathy (DPN) is a major complication of type 2 diabetes mellitus (T2D) that reduces quality of life and increases the risk of foot ulcers and amputations.
Jae-Hyung Park +6 more
doaj +2 more sources
Baseline Blood Levels of Mucin-1 Are Associated with Crucial On-Treatment Adverse Outcomes in Patients with Idiopathic Pulmonary Fibrosis Receiving Antifibrotic Pirfenidone [PDF]
Mucin-1 is a multi-functional glycoprotein expressed by type II alveolocytes and may be detectable in the circulation following pulmonary fibrosis. The prognostic utility of baseline pre-treatment blood levels of mucin-1 in patients with idiopathic ...
Tang-Hsiu Huang +7 more
doaj +2 more sources
Mucin-1 and its relation to grade, stage and survival in ovarian carcinoma patients
Background Mucin-1 is known to be over-expressed by various human carcinomas and is shed into the circulation where it can be detected in patient’s serum by specific anti-Mucin-1 antibodies, such as the tumour marker assays CA 15–3 and CA 27.29.
Engelstaedter Verena +11 more
doaj +2 more sources
Expression of cyclooxygenase‑2 and mucin 1 in colorectal cancer [PDF]
In colorectal cancer (CRC), pathological factors that correlate with negative prognosis include, among others, overexpression of cyclooxygenase-2 (COX-2) and abundant expression of mucin 1 (MUC1). COX-2 overexpression may therefore be associated with MUC1 overexpression.
Małgorzata Szlendak +7 more
openaire +4 more sources

