Results 21 to 30 of about 29,844,027 (286)

Asynchrony of Apical Polarization, Luminogenesis, and Functional Differentiation in the Developing Thyroid Gland

Frontiers in Endocrinology, 2021
Follicular thyroid tissue originates from progenitors derived from a midline endodermal primordium. Current understanding infers that folliculogenesis in the embryonic thyroid designates the latest morphogenetic event taking place after the final ...
Ellen Johansson, Shawn Liang, Carmen Moccia, Therese Carlsson, Daniel Andersson, Henrik Fagman, Henrik Fagman, Henrik Fagman, Mikael Nilsson   +8 more
doaj   +1 more source

⁸⁹Zr-Labeled AR20.5: A MUC1-Targeting ImmunoPET Probe

Molecules, 2020
High expression levels of the tumor-associated antigen MUC1 have been correlated with tumor aggressiveness, poor response to therapy, and poor survival in several tumor types, including breast, pancreatic, and epithelial ovarian cancer. Herein, we report
Kimberly Fung, Delphine Vivier, Outi Keinänen, Elaheh Khozeimeh Sarbisheh, Eric W. Price, Brian M. Zeglis   +5 more
doaj   +1 more source

Differential expression of mucin 1 and mucin 2 in colorectal cancer

World Journal of Gastroenterology, 2018
To determine tissue expression (mRNA, protein) of two types of mucins [mucin 1 (MUC1) and mucin 2 (MUC2)] in patients with colorectal cancer (CRC).Expression of membrane-bound mucin (MUC1) and secretory mucin (MUC2) in CRC (mRNA, protein) were analyzed in tissue material including fragments of tumors obtained from CRC patients (n = 34), and fragments ...
Kasprzak, Aldona, Siodła, Elżbieta, Andrzejewska, Małgorzata, Szmeja, Jacek, Seraszek-Jaros, Agnieszka, Cofta, Szczepan, Szaflarski, Witold   +6 more
openaire   +2 more sources

Fibronectin in human gallbladder bile: cholesterol pronucleating and/or mucin "link" protein? [PDF]

, 1994
Some biliary proteins (pronucleators) seem to be essential factors for cholesterol crystal formation and crystal growth in bile. A recent study suggests that fibronectin is such a pronucleator in bile.
Ritter, Christoph von, Lange, Volker, Del Pozo, Reginals, Paumgartner, Gustav, V. Lange, J. F. Miquel, R. Del Pozo, G. Paumgartner, Jüngst, Dieter, Miquel, Juan Francisco, C. Von Ritter, D. Jungst   +11 more
core   +1 more source

Expression of aberrantly glycosylated Mucin‐1 in ovarian cancer [PDF]

Histopathology, 2010
Van Elssen C H M J, Frings P W H, Bot F J, Van de Vijver K K, Huls M B, Meek B, Hupperets P, Germeraad W T V & Bos G M J
(2010) Histopathology57, 597–606
Expression of aberrantly glycosylated Mucin‐1 in ovarian cancerAims:  Mucin 1 (MUC1) is an important tumour‐associated antigen (TAA), both overexpressed and aberrantly glycosylated in ...
Van Elssen, Catharina H. M. J., Frings, Peter W. H., Bot, Freek J., Van de Vijver, Koen K., Huls, Mariska B., Meek, Bob, Hupperets, Pierre, Germeraad, Wilfred T. V., Bos, Gerard M. J.   +8 more
openaire   +3 more sources

Clinicopathological Factors Affecting Mucin 1, Mucin 2, and Mucin 5AC Staining in Patients who Underwent Resection for Colorectal Cancer

Journal of the College of Physicians and Surgeons Pakistan, 2023
To investigate the clinicopathological factors affecting mucins (MUC 1, MUC 2, and MUC 5AC) staining in patients who underwent resection for colorectal cancer.An observational study. Place and Duration of the Study: Department of General Surgery and Department of Pathology, Kafkas University Faculty of Medicine, Kars, Turkey, between January 2020 and ...
Turgut, Anuk, Hatice, Beseren, Yalcin, Polat, Ozkan, Ozden, Tolga, Kalayci   +4 more
openaire   +2 more sources

Adeno-associated virus-based caveolin-1 delivery via different routes for the prevention of cholesterol gallstone formation

Lipids in Health and Disease, 2022
Background Hepatic caveolin-1 (CAV1) is reduced in cholesterol gallstone disease (CGD). Mice with CAV1 deficiency were prone to develop CGD. However, it remains unknown whether restored hepatic CAV1 expression prevents the development of CGD.
Sha Li, Hongtan Chen, Xin Jiang, Fengling Hu, Yiqiao Li, Guoqiang Xu   +5 more
doaj   +1 more source

Sensitivity of Human Intrahepatic Cholangiocarcinoma Subtypes to Chemotherapeutics and Molecular Targeted Agents: A Study on Primary Cell Cultures. [PDF]

PLoS ONE, 2015
We investigated the sensitivity of intrahepatic cholangiocarcinoma (IHCCA) subtypes to chemotherapeutics and molecular targeted agents. Primary cultures of mucin- and mixed-IHCCA were prepared from surgical specimens (N.
Alice Fraveto, Vincenzo Cardinale, Maria Consiglia Bragazzi, Felice Giuliante, Agostino Maria De Rose, Gian Luca Grazi, Chiara Napoletano, Rossella Semeraro, Anna Maria Lustri, Daniele Costantini, Lorenzo Nevi, Sabina Di Matteo, Anastasia Renzi, Guido Carpino, Eugenio Gaudio, Domenico Alvaro   +15 more
doaj   +1 more source

Primary breast cancer biomarkers based on glycosylation and extracellular vesicles detected from human serum

Cancer Reports, 2022
Background Breast cancer is a very common cancer that can be severe if not discovered early. The current tools to detect breast cancer need improvement. Cancer has a universal tendency to affect glycosylation.
Joonas Terävä, Alejandra Verhassel, Orsola Botti, Md. Khirul Islam, Janne Leivo, Saara Wittfooth, Pirkko Härkönen, Kim Pettersson, Kamlesh Gidwani   +8 more
doaj   +1 more source

Mucin 1 expression correlation with lymph node metastasis and micrometastasis and poor prognosis in patients with esophageal squamous cell carcinomas

Archives of Medical Science, 2019
Introduction Lymph node metastasis (LNM) and lymph node micrometastasis (LNMM) are prognostic factors in esophageal squamous cell carcinoma (ESCC) patients.
Fei Yang, Zhe Li, Jing-Bo Shao, Wei Gao, Zhi-Gang Sun   +4 more
doaj   +1 more source