Results 21 to 30 of about 131,847 (255)

Expression of aberrantly glycosylated Mucin‐1 in ovarian cancer [PDF]

Histopathology, 2010
Van Elssen C H M J, Frings P W H, Bot F J, Van de Vijver K K, Huls M B, Meek B, Hupperets P, Germeraad W T V & Bos G M J
(2010) Histopathology57, 597–606
Expression of aberrantly glycosylated Mucin‐1 in ovarian cancerAims:  Mucin 1 (MUC1) is an important tumour‐associated antigen (TAA), both overexpressed and aberrantly glycosylated in ...
Van Elssen, Catharina H. M. J., Frings, Peter W. H., Bot, Freek J., Van de Vijver, Koen K., Huls, Mariska B., Meek, Bob, Hupperets, Pierre, Germeraad, Wilfred T. V., Bos, Gerard M. J.   +8 more
openaire   +3 more sources

Clinicopathological Factors Affecting Mucin 1, Mucin 2, and Mucin 5AC Staining in Patients who Underwent Resection for Colorectal Cancer

Journal of the College of Physicians and Surgeons Pakistan, 2023
To investigate the clinicopathological factors affecting mucins (MUC 1, MUC 2, and MUC 5AC) staining in patients who underwent resection for colorectal cancer.An observational study. Place and Duration of the Study: Department of General Surgery and Department of Pathology, Kafkas University Faculty of Medicine, Kars, Turkey, between January 2020 and ...
Turgut, Anuk, Hatice, Beseren, Yalcin, Polat, Ozkan, Ozden, Tolga, Kalayci   +4 more
openaire   +2 more sources

Adeno-associated virus-based caveolin-1 delivery via different routes for the prevention of cholesterol gallstone formation

Lipids in Health and Disease, 2022
Background Hepatic caveolin-1 (CAV1) is reduced in cholesterol gallstone disease (CGD). Mice with CAV1 deficiency were prone to develop CGD. However, it remains unknown whether restored hepatic CAV1 expression prevents the development of CGD.
Sha Li, Hongtan Chen, Xin Jiang, Fengling Hu, Yiqiao Li, Guoqiang Xu   +5 more
doaj   +1 more source

Sensitivity of Human Intrahepatic Cholangiocarcinoma Subtypes to Chemotherapeutics and Molecular Targeted Agents: A Study on Primary Cell Cultures. [PDF]

PLoS ONE, 2015
We investigated the sensitivity of intrahepatic cholangiocarcinoma (IHCCA) subtypes to chemotherapeutics and molecular targeted agents. Primary cultures of mucin- and mixed-IHCCA were prepared from surgical specimens (N.
Alice Fraveto, Vincenzo Cardinale, Maria Consiglia Bragazzi, Felice Giuliante, Agostino Maria De Rose, Gian Luca Grazi, Chiara Napoletano, Rossella Semeraro, Anna Maria Lustri, Daniele Costantini, Lorenzo Nevi, Sabina Di Matteo, Anastasia Renzi, Guido Carpino, Eugenio Gaudio, Domenico Alvaro   +15 more
doaj   +1 more source

Primary breast cancer biomarkers based on glycosylation and extracellular vesicles detected from human serum

Cancer Reports, 2022
Background Breast cancer is a very common cancer that can be severe if not discovered early. The current tools to detect breast cancer need improvement. Cancer has a universal tendency to affect glycosylation.
Joonas Terävä, Alejandra Verhassel, Orsola Botti, Md. Khirul Islam, Janne Leivo, Saara Wittfooth, Pirkko Härkönen, Kim Pettersson, Kamlesh Gidwani   +8 more
doaj   +1 more source

Mucin-1 and its relation to grade, stage and survival in ovarian carcinoma patients

BMC Cancer, 2012
Background Mucin-1 is known to be over-expressed by various human carcinomas and is shed into the circulation where it can be detected in patient’s serum by specific anti-Mucin-1 antibodies, such as the tumour marker assays CA 15–3 and CA 27.29.
Engelstaedter Verena, Heublein Sabine, Schumacher Anamur Lan, Lenhard Miriam, Engelstaedter Helen, Andergassen Ulrich, Guenthner-Biller Margit, Kuhn Christina, Rack Brigitte, Kupka Markus, Mayr Doris, Jeschke Udo   +11 more
doaj   +1 more source

Mucin-degrading gut commensals isolated from healthy faecal donor suppress intestinal epithelial inflammation and regulate tight junction barrier function

Frontiers in Immunology, 2022
The intestinal epithelium surface is covered by a layer of mucus that harbors a complex and dynamic population of bacteria termed gut microbiota. In particular, some gut bacteria have the ability to degrade the mucin glycan for nutritional sources ...
Mingfang Pan, Nilakshi Barua, Margaret Ip, Margaret Ip   +3 more
doaj   +1 more source

Nutritional Studies on Mucin (Part 1)

Eiyo To Shokuryo, 1967
ムチンのラット成長に及ぼす影響について検討し次の如き結果を得た。1) Mucin-1を5%添加したラット群ではcontrolに対し23.5%, SM 5%添加群に対し17.2%大きい体重増加がみられ, Food efficiencyも高められた。一方粘度の低いMucin-2を添加したM-2群には体重増加作用は見られなかった。2) トレッドミルによる運動能力測定ではムチン添加群がcontrolよりも1.5～1.7倍大きな走行距離を示した。3) 臓器重量においては何ら顕著な差異は認められなかった。4) Mucin-1添加群において, 若干の血清蛋白量の増加傾向が見られたが, その他には顕著な変動は見られなかった。
Taro Nagasawa, Isao Kiyosawa, Masami Maeda, Mamoru Niyomura   +3 more
openaire   +3 more sources

Serum Krebs von den Lungen-6 before treatment predicts the prognosis of lung cancer in Asian populations: a systematic review and meta-analysis

Frontiers in Immunology
BackgroundUp until now, no clear consensus has been reached on the role of serum Krebs von den Lungen-6 (KL-6) levels in predicting survival in patients with lung cancer. This meta-analysis aimed to assess the prognostic value of serum KL-6 levels before
Hong Huang, Liangyu Fu, Chenye Feng, Jiawei Zhou, Jiahuan Xu, Jianjun Sun, Ying Pan, Delei Kong, Wei Wang   +8 more
doaj   +1 more source

Investigation of the Effect of Alkali Modification of Mucin on Some Properties of Metronidazole Bioadhesive Tablets

Journal of Applied Sciences and Environmental Management, 2015
The objective of this study was to investigate the effect of alkali treatment of mucin on the mucoadhesive properties and tablet parameters of metronidazole tablets.
SO Eraga, MI Arhewoh, CO Okogbenin, MA Iwuagwu   +3 more
doaj   +1 more source