Results 51 to 60 of about 191,997 (296)

Effect of hydrolyzed milk on the adhesion of Lactobacilli to intestinal cells [PDF]

, 2015
Milk is an essential part of the human diet and is undoubtedly a major calcium source in human nutrition, accepted well by most individuals. Knowledge on how the components from dairy products support or reduce the adherence of probiotics to the ...
Doskočil, I., Geigerová, M., Havlik, J., Rada, V., Volštátová, T.   +4 more
core   +1 more source

Identification and characterisation of enteroaggregative Escherichia coli subtypes associated with human disease [PDF]

, 2020
Enteroaggregative E. coli (EAEC) are a major cause of diarrhoea worldwide. Due to their heterogeneity and carriage in healthy individuals, identification of diagnostic virulence markers for pathogenic strains has been difficult.
Brett, Bernard, Bundy, Leah, Chattaway, Marie A., Crossman, Lisa C., Ellis, Samuel J., Hölken, Johanna M., Kay, Gemma L., McGrath, Conor J., Schüller, Stephanie, Wain, John   +9 more
core   +1 more source

Proteomic analysis of Bifidobacterium longum subsp. infantis reveals the metabolic insight on consumption of prebiotics and host glycans. [PDF]

, 2013
Bifidobacterium longum subsp. infantis is a common member of the intestinal microbiota in breast-fed infants and capable of metabolizing human milk oligosaccharides (HMO).
An, Hyun Joo, Garrido, Daniel, German, J Bruce, Kim, Jae-Han, Lebrilla, Carlito B, Mills, David A   +5 more
core   +8 more sources

The role of epidermal growth factor-like module containing mucin-like hormone receptor 2 in human cancers. [PDF]

, 2014
G-protein coupled receptors (GPCRs) are among the most diverse and ubiquitous proteins in all of biology. The epidermal growth factor-seven span transmembrane (EGF-TM7) subfamily of adhesion GPCRs is a small subset whose members are mainly expressed on ...
Bloch, Orin, Ivan, Michael E, Kaur, Gurvinder, Oh, Michael C, Oh, Taemin, Parsa, Andrew T, Safaee, Michael, Sayegh, Eli T, Sun, Matthew Z   +8 more
core   +2 more sources

Mucin 1 deficiency mediates corticosteroid insensitivity in asthma

Allergy, 2018
AbstractBackgroundThe loss of corticosteroid efficacy is an important issue in severe asthma management and may lead to poor asthma control and deterioration of airflow. Recent data indicate that Mucin 1 (MUC1) membrane mucin can mediate corticosteroid efficacy in chronic rhinosinusitis, but the role of MUC1 in uncontrolled severe asthma is unknown ...
Javier Milara, Anselm Morell, Alfredo de Diego, Enrique Artigues, Esteban Morcillo, Julio Cortijo   +5 more
openaire   +7 more sources

Lubiprostone stimulates small intestinal mucin release

BMC Gastroenterology, 2012
Background Lubiprostone is a synthetic bicyclic fatty acid derivative of prostaglandin E1 (PGE1) used for chronic constipation. The best known action of lubiprostone is simulation of Cl- dependent fluid secretion.
De Lisle Robert C
doaj   +1 more source

Incorporating a mucosal environment in a dynamic gut model results in a more representative colonization by lactobacilli [PDF]

, 2011
To avoid detrimental interactions with intestinal microbes, the human epithelium is covered with a protective mucus layer that traps host defence molecules. Microbial properties such as adhesion to mucus further result in a unique mucosal microbiota with
Derde, Melanie, Eeckhaut, Venessa, MacKenzie, Donald A, Marzorati, Massimo, Possemiers, Sam, Roos, Stefaan, Van de Wiele, Tom, Van den Abbeele, Pieter, Van Immerseel, Filip, Vanhoecke, Barbara, Verstraete, Willy   +10 more
core   +2 more sources

Nutritional Studies on Mucin (Part 1)

Eiyo To Shokuryo, 1967
ムチンのラット成長に及ぼす影響について検討し次の如き結果を得た。1) Mucin-1を5%添加したラット群ではcontrolに対し23.5%, SM 5%添加群に対し17.2%大きい体重増加がみられ, Food efficiencyも高められた。一方粘度の低いMucin-2を添加したM-2群には体重増加作用は見られなかった。2) トレッドミルによる運動能力測定ではムチン添加群がcontrolよりも1.5～1.7倍大きな走行距離を示した。3) 臓器重量においては何ら顕著な差異は認められなかった。4) Mucin-1添加群において, 若干の血清蛋白量の増加傾向が見られたが, その他には顕著な変動は見られなかった。
Taro Nagasawa, Isao Kiyosawa, Masami Maeda, Mamoru Niyomura   +3 more
openaire   +2 more sources

Tim-1 mucin domain-mutant mice display exacerbated atherosclerosis

Atherosclerosis, 2022
Increasing evidence has shown that immune checkpoint molecules of the T-cell immunoglobulin and mucin domain (Tim) family are associated with diverse physiologic and pathologic processes. Previous studies of the role of Tim-1 in atherosclerosis using anti-Tim-1 antibodies have yielded contradictory results.
Douna, H., Smit, V., Puijvelde, G.H.M. van, Kiss, M.G., Binder, C.J., Bot, I., Kuchroo, V.K., Lichtman, A.H., Kuiper, J., Foks, A.C.   +9 more
openaire   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source