Results 21 to 30 of about 32,014 (250)

miR-let-7b and miR-let-7c suppress tumourigenesis of human mucosal melanoma and enhance the sensitivity to chemotherapy

Journal of Experimental & Clinical Cancer Research, 2019
Background Mucosal melanoma with poor prognosis is a common histopathologic subtype of melanoma among Chinese and other Asian peoples. Regulated microRNAs (miRNAs) have been reported as oncogenes or tumour suppressors in melanoma.
Huan Tang, Meng Ma, Jie Dai, Chuanliang Cui, Lu Si, Xinan Sheng, Zhihong Chi, Longwen Xu, Sifan Yu, Tianxiao Xu, Junya Yan, Huan Yu, Lu Yang, Yan Kong, Jun Guo   +14 more
doaj   +1 more source

Sinonasal mucosal melanomas

European Annals of Otorhinolaryngology, Head and Neck Diseases, 2010
Sinonasal mucosal melanomas account for approximately 1% of all melanomas. These tumors are particularly aggressive, with a recurrence rate between 37 and 54% and a 5-year survival rate between 20 and 46%. Metastases are frequent. The main objective of this study was to analyze all of our cases of sinonasal mucosal melanomas and determine any ...
Liétin, B., Montalban, A., Louvrier, C., Kemeny, J.-L., Mom, T., Gilain, L.   +5 more
openaire   +2 more sources

Sequential Combination Chemotherapy of Dacarbazine (DTIC) with Carboplatin and Paclitaxel for Patients with Metastatic Mucosal Melanoma of Nasal Cavity and Paranasal Sinuses

Clinical Medicine Insights: Case Reports, 2017
By the recent introduction of molecular targeting drugs against BRAF mutation and immune checkpoint inhibitors, the prognosis of patients with melanoma in advanced stage is now improving, but still in the minority.
W. Omata, A. Tsutsumida, K. Namikawa, A. Takahashi, K. Oashi, N. Yamazaki   +5 more
doaj   +1 more source

Anorectal mucosal melanoma

Oncotarget, 2018
Anorectal melanoma is an uncommon and aggressive mucosal melanocytic malignancy. Due to its rarity, the pre-operative diagnosis remains difficult. The first symptoms are non-specific such as anal bleeding, anal mass or pain. Although anorectal melanoma carries a poor prognosis; optimal therapeutics strategies are unclear. Surgical resection remains the
Malaguarnera G, Madeddu R, Catania Vito E, Bertino G, Morelli L, Perrotta R, Drago F, Malaguarnera M, Latteri S   +8 more
openaire   +6 more sources

Advances in Understanding Spontaneously Occurring Melanoma in Animals

Veterinary Sciences, 2023
Melanoma is a tumour that arises from the uncontrolled proliferation of melanocytes (pigment-producing cells) found in the skin (cutaneous melanoma and digital melanoma), mucosal surfaces (oral melanoma), and the eye (ocular melanoma) [...]
Kelly L. Blacklock, Louise van der Weyden   +1 more
doaj   +1 more source

Mucosal Melanoma: An Update

Actas Dermo-Sifiliográficas (English Edition), 2015
Mucosal melanoma is a rare melanoma subtype that differs from the cutaneous form of the tumor in its biology, clinical manifestations, and management. Diagnosis is usually late due to a lack of early or specific signs and the location of lesions in areas that are difficult to access on physical examination.
Ballester Sánchez R, de Unamuno Bustos B, Navarro Mira M, Botella Estrada R   +3 more
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Up-Regulation of PARP1 Expression Significantly Correlated with Poor Survival in Mucosal Melanomas

Cells, 2020
Introduction: Mucosal melanoma is rare and associated with poorer prognosis in comparison to conventional melanoma subtypes. Little is known about the prognostic significance as well as possible associations between PARP1 and immunologic response in ...
Piotr Donizy, Cheng-Lin Wu, Jason Mull, Masakazu Fujimoto, Agata Chłopik, Yan Peng, Sara C. Shalin, M. Angelica Selim, Susana Puig, Maria-Teresa Fernandez-Figueras, Christopher R. Shea, Wojciech Biernat, Janusz Ryś, Andrzej Marszalek, Mai P. Hoang   +14 more
doaj   +1 more source

A case report: Primary malignant melanoma of the glottic larynx – A very rare entity

Otolaryngology Case Reports, 2023
Background: Primary mucosal melanoma of the larynx is an extremely rare entity. Our case represents the seventeenth case reported to date globally, and the first Canadian case to be reported.
You Sung Nam, Martin J. Bullock, David Forner, Matthew H. Rigby, Martin Corsten, Jonathan R.B. Trites, S. Mark Taylor   +6 more
doaj   +1 more source

Mucosal Melanoma of the Head and Neck [PDF]

Journal of the National Comprehensive Cancer Network, 2012
Overview Mucosal melanoma (MM) is a rare, very aggressive noncutaneous melanoma that affects the upper aerodigestive tract, genitourinary tract, and anal/rectal region.1 This portion of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Head and Neck (H&N) Cancers only describes MMs of the H&N, which constitute fewer than 10% of ...
David G, Pfister, Kie-Kian, Ang, David M, Brizel, Barbara, Burtness, Anthony J, Cmelak, A Dimitrios, Colevas, Frank, Dunphy, David W, Eisele, Jill, Gilbert, Maura L, Gillison, Robert I, Haddad, Bruce H, Haughey, Wesley L, Hicks, Ying J, Hitchcock, Merrill S, Kies, William M, Lydiatt, Ellie, Maghami, Renato, Martins, Thomas, McCaffrey, Bharat B, Mittal, Harlan A, Pinto, John A, Ridge, Sandeep, Samant, Giuseppe, Sanguineti, David E, Schuller, Jatin P, Shah, Sharon, Spencer, Andrea, Trotti, Randal S, Weber, Gregory, Wolf, Frank, Worden   +30 more
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Immunotherapy for mucosal melanoma

Annals of Translational Medicine, 2019
Mucosal melanoma is a rare subtype, representing 1% of all melanoma diagnoses (1). As compared to cutaneous melanoma, patients with mucosal melanoma often present with more advanced disease and prognosis is significantly worse (2).
Sarah, Yentz, Christopher D, Lao
openaire   +2 more sources