Results 31 to 40 of about 32,014 (250)
Noncutaneous malignant melanoma: a prognostic model from a retrospective multicenter study
BMC Cancer, 2010 Background We performed multicenter study to define clinical characteristics of noncutaneous melanomas and to establish prognostic factors patients who received curative resection.
Kim Jung Han +10 more
doaj +1 more source
Mucosal Melanoma: Pathological Evolution, Pathway Dependency and Targeted Therapy
Frontiers in Oncology, 2021 Mucosal melanoma (MM) is a rare melanoma subtype that originates from melanocytes within sun-protected mucous membranes. Compared with cutaneous melanoma (CM), MM has worse prognosis and lacks effective treatment options.
Yanni Ma +7 more
doaj +1 more source
Sinonasal Mucosal Melanoma: An Enigma
Philippine Journal of Otolaryngology Head and Neck Surgery, 2011 Objective: To report two cases of mucosal melanoma of the sinonasal cavity from India and review the literature emphasizing current important clinical and biologic aspects of this tumor.
Hidayat Ullah, Mirza Qaisar Baig
doaj +1 more source
Characterization of Primary Cultures of Normal and Neoplastic Canine Melanocytes
Animals, 2021 Although numerous animal models, especially mouse models, have been established for the study of melanoma, they often fail to accurately describe the mechanisms of human disease because of their anatomic, physiological, and immune differences.
Monica Sforna +6 more
doaj +1 more source
Ki67 Antigen as a Predictive Factor for Prognosis of Sinonasal Mucosal Melanoma [PDF]
Clinical and Experimental Otorhinolaryngology, 2008 ObjectivesSinonasal mucosal melanoma is a rare and aggressive disease. The aim of this study was to analyze the clinical features of patients with sinonasal mucosal melanoma and to determine the role of Ki67 antigen as a predictor of prognosis in ...
Dong-Kyu Kim +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Journal of Medical Case ReportsBackground Mucosal melanoma, an aggressive type of malignancy different from the cutaneous melanomas commonly seen in the head and neck region, represents
Saurabh D. Chitnis +2 more
doaj +1 more source
A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity
Advanced Science, EarlyView.This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu +16 more
wiley +1 more source
Mucosal melanoma – diagnostic challenge
Przegląd DermatologicznyMucosal melanoma malignum (mMM) is a rare and aggressive malignancy that carries a poor prognosis. Most commonly, it develops on the mucous membranes in the head and neck region, and within the genitalia. Because of its anatomical location and absence of
Paulina Karp +2 more
doaj +1 more source
Advanced Science, EarlyView.This research identifies DTX3L as a critical tumor suppressor that inhibits epithelial‐mesenchymal transition (EMT), invasion and metastasis in gastric cancer. By functioning as an E3 ubiquitin ligase, DTX3L targets the master EMT regulator SNAI1 for GSK‐3β‐dependent proteasomal degradation.
Yang Chen +7 more
wiley +1 more source