Results 31 to 40 of about 305,145 (241)

Proton beam radiotherapy in the management of uveal melanoma: clinical experience in Scotland [PDF]

, 2008
<p>Aim: To evaluate proton-beam radiotherapy (PBRT) in the management of uveal melanoma in Scotland.</p> <p>Methods: A retrospective review was undertaken on all patients receiving PBRT for uveal melanoma (1994–2005).
McConnachie, A., Alex Taylor, Alex Kacperek, Aziz, S., Samir Aziz, Kemp, E., Andrzej McConnachie, Ewan Kemp, Kacperek, A., Taylor, A.   +9 more
core   +1 more source

Noncutaneous malignant melanoma: a prognostic model from a retrospective multicenter study

BMC Cancer, 2010
Background We performed multicenter study to define clinical characteristics of noncutaneous melanomas and to establish prognostic factors patients who received curative resection.
Kim Jung Han, Lee Soon Il, Lim Do Hyoung, Park Keon Woo, Oh Sung Yong, Jun Hyun Jung, Kim Eun Kyoung, Kim Hyo Song, Kim Kyoung Mee, Lee Dae Ho, Lee Jeeyun   +10 more
doaj   +1 more source

Prospects for non-immunological molecular therapeutics in melanoma [PDF]

, 2010
In 2006 there were 60,000 new cases of cutaneous melanoma in the European Union and 13,000 deaths (www.europeancancerleagues.org). Currently available systemic treatment options for metastatic melanoma, including both cytotoxic and immunologic therapies,
Tryfonopoulos, Dimitrios, Eustace, Alexander J., Mahgoub, Thamir, O\u27Donovan, Norma, Crown, John, O'Donovan, Norma   +5 more
core   +2 more sources

Sinonasal Mucosal Melanoma: An Enigma

Philippine Journal of Otolaryngology Head and Neck Surgery, 2011
Objective: To report two cases of mucosal melanoma of the sinonasal cavity from India and review the literature emphasizing current important clinical and biologic aspects of this tumor.
Hidayat Ullah, Mirza Qaisar Baig
doaj   +1 more source

A case report: Primary malignant melanoma of the glottic larynx – A very rare entity

Otolaryngology Case Reports, 2023
Background: Primary mucosal melanoma of the larynx is an extremely rare entity. Our case represents the seventeenth case reported to date globally, and the first Canadian case to be reported.
You Sung Nam, Martin J. Bullock, David Forner, Matthew H. Rigby, Martin Corsten, Jonathan R.B. Trites, S. Mark Taylor   +6 more
doaj   +1 more source

The molecular profile of mucosal melanoma

, 2020
Herein, we wanted to explore the molecular landscape of mucosal melanoma from different sites and identify potential molecular targets for future therapy. Mucosal melanomas (N = 40) from different sites (conjunctiva, sinonasal cavity, rectum, and vagina)
Lauge Hjorth Mikkelsen, Christian von Buchwald, Steffen Heegaard, Peter Bjerre Toft, Mikkelsen, Lauge Hjorth, von Buchwald, Christian, Maag, Emil, Andersen, Mette Klarskov, Kruhøffer, Mogens, Larsen, Ann Cathrine, Heegaard, Steffen, Mette Klarskov Andersen, Mogens Kruhøffer, Emil Maag, Linea Cecilie Melchior, Ann-Cathrine Larsen, Karin Wadt, Melchior, Linea Cecilie, Toft, Peter Bjerre, Wadt, Karin   +19 more
core   +1 more source

Mucosal Melanoma: Pathological Evolution, Pathway Dependency and Targeted Therapy

Frontiers in Oncology, 2021
Mucosal melanoma (MM) is a rare melanoma subtype that originates from melanocytes within sun-protected mucous membranes. Compared with cutaneous melanoma (CM), MM has worse prognosis and lacks effective treatment options.
Yanni Ma, Yanni Ma, Ronghui Xia, Xuhui Ma, Robert L. Judson-Torres, Robert L. Judson-Torres, Hanlin Zeng, Hanlin Zeng   +7 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Local intralesional talimogene laherparepvec therapy with complete local response in oral palatine mucosal melanoma: a case report

Journal of Medical Case Reports
Background Mucosal melanoma, an aggressive type of malignancy different from the cutaneous melanomas commonly seen in the head and neck region, represents 
Saurabh D. Chitnis, Nolan B. Seim, Kari Kendra   +2 more
doaj   +1 more source

Characterization of Primary Cultures of Normal and Neoplastic Canine Melanocytes

Animals, 2021
Although numerous animal models, especially mouse models, have been established for the study of melanoma, they often fail to accurately describe the mechanisms of human disease because of their anatomic, physiological, and immune differences.
Monica Sforna, Elisabetta Chiaradia, Ilaria Porcellato, Serenella Silvestri, Giulia Moretti, Luca Mechelli, Chiara Brachelente   +6 more
doaj   +1 more source