Worldwide Cutaneous Malignant Melanoma Incidences Analyzed by Sex, Age, and Skin Type Over Time (1955–2007): Is HPV Infection of Androgenic Hair Follicular Melanocytes a Risk Factor for Developing Melanoma Exclusively in People of European-Ancestry? [PDF]
, 2016 The cutaneous malignant melanoma (CMM) incidence has been increasing in an exponential manner in certain populations around the world for over 7 decades.
Merrill, Stephen +2 more
core +3 more sources
Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response. [PDF]
, 2019 Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and confers a poor prognosis. Beyond standard systemic therapy with multikinase inhibitors, recent studies demonstrate the potential for robust and durable responses ...
Fong, Lawrence +2 more
core +2 more sources
Anorectal malignant mucosal melanoma
Ghana Medical Journal, 2022 Anorectal mucosal melanoma (AMM) is a rare, aggressive malignancy. The symptoms of AMM mimic common benign conditions in the anus, such as haemorrhoids; hence diagnosis is often made late, a third of patients having metastasis at first presentation.
A. Bediako-Bowan, Antoinette +8 more
openaire +3 more sources
Advances in Understanding Spontaneously Occurring Melanoma in Animals
Veterinary Sciences, 2023 Melanoma is a tumour that arises from the uncontrolled proliferation of melanocytes (pigment-producing cells) found in the skin (cutaneous melanoma and digital melanoma), mucosal surfaces (oral melanoma), and the eye (ocular melanoma) [...]
Kelly L. Blacklock +1 more
doaj +1 more source
Treatment of Primary and Metastatic Multifocal Mucosal Melanoma of the Oral Cavity with Imatinib [PDF]
, 2017 BACKGROUND: Mucosal melanoma of the oral cavity is a rare entity and accounts for less than 1\u20133% of all melanomas. Contrary to cutaneous melanoma, primary oral melanoma more commonly harbors mutations in c-KIT.
Deinlein, Teresa +6 more
core +2 more sources
Up-Regulation of PARP1 Expression Significantly Correlated with Poor Survival in Mucosal Melanomas
Cells, 2020 Introduction: Mucosal melanoma is rare and associated with poorer prognosis in comparison to conventional melanoma subtypes. Little is known about the prognostic significance as well as possible associations between PARP1 and immunologic response in ...
Piotr Donizy +14 more
doaj +1 more source
A case report: Primary malignant melanoma of the glottic larynx – A very rare entity
Otolaryngology Case Reports, 2023 Background: Primary mucosal melanoma of the larynx is an extremely rare entity. Our case represents the seventeenth case reported to date globally, and the first Canadian case to be reported.
You Sung Nam +6 more
doaj +1 more source
A case report: retigabine induced oral mucosal dyspigmentation of the hard palate [PDF]
, 2015 Background Dyspigmentation of the oral mucosa has a multitude of aetiological causes. Retigabine, a new antiepileptic drug, has the potential side effect of inducing a blue/purple pigmentation of the oral mucosa in addition to the skin, lips, nails and ...
Beacher, Nicholas G. +2 more
core +1 more source
Mucosal Melanoma: Pathological Evolution, Pathway Dependency and Targeted Therapy
Frontiers in Oncology, 2021 Mucosal melanoma (MM) is a rare melanoma subtype that originates from melanocytes within sun-protected mucous membranes. Compared with cutaneous melanoma (CM), MM has worse prognosis and lacks effective treatment options.
Yanni Ma +7 more
doaj +1 more source
Transplantable melanomas in hamsters and gerbils as models for human melanoma : sensitization in melanoma radiotherapy : from animal models to clinical trials [PDF]
, 2018 The focus of the present review is to investigate the role of melanin in the radioprotection of melanoma and attempts to sensitize tumors to radiation by inhibiting melanogenesis. Early studies showed radical scavenging, oxygen consumption and adsorption
Andrzej Słominski +11 more
core +1 more source