Results 131 to 140 of about 829 (144)
DNA Reshaping by MukB RIGHT-HANDED KNOTTING, LEFT-HANDED SUPERCOILING [PDF]
Journal of Biological Chemistry, 2006 MukB is a bacterial SMC (structural maintenance of chromosome) protein required for faithful chromosome segregation in Escherichia coli. We report here that purified MukB introduces right-handed knots into DNA in the presence of type-2 topoisomerase, indicating that the protein promotes intramolecular DNA condensation.
Valentin V Rybenkov, Zoya M Petrushenko
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MukB acts as a macromolecular clamp in DNA condensation
Nature Structural & Molecular Biology, 2008Correct folding of the chromosome into its highly ordered structure requires the action of condensins. The multisubunit condensins are highly conserved from bacteria to humans, and at their core they contain the characteristic V-shaped dimer of structural maintenance of chromosome proteins.
Yuanbo, Cui +2 more
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A Repeated Coiled-Coil Interruption in the Escherichia coli Condensin MukB
Journal of Molecular Biology, 2011MukB, a divergent structural maintenance of chromosomes (SMC) protein, is important for chromosome segregation and condensation in Escherichia coli and other γ-proteobacteria. MukB and canonical SMC proteins share a common five-domain structure in which globular N- and C-terminal regions combine to form an ATP-binding-cassette-like ATPase domain.
Christopher S, Weitzel +3 more
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The bacterial condensin MukB compacts DNA by sequestering supercoils and stabilizing topologically isolated loops [PDF]
Journal of Biological Chemistry, 2017 MukB is a structural maintenance of chromosome-like protein required for DNA condensation. The complete condensin is a large tripartite complex of MukB, the kleisin, MukF, and an accessory protein, MukE. As found previously, MukB DNA condensation is a stepwise process. We have defined these steps topologically.
Rupesh Kumar +2 more
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Molecular Microbiology, 1994
SummaryThe mukB gene codes for a 177kDa protein, which might be a candidate for a force‐generating enzyme in chromosome positioning in Escherichia coli. The mukB106 mutant produces normal‐sized, anucleate cells and shows a temperature‐sensitive colony formation.
K, Yamanaka +4 more
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SummaryThe mukB gene codes for a 177kDa protein, which might be a candidate for a force‐generating enzyme in chromosome positioning in Escherichia coli. The mukB106 mutant produces normal‐sized, anucleate cells and shows a temperature‐sensitive colony formation.
K, Yamanaka +4 more
openaire +2 more sources
2023
ABSTRACT The bacterial condensin MukB facilitates proper chromosome segregation in Escherichia coli . A portion of the MukB proteins localize at a specific chromosome region, binding to DNA in a non-sequence-specific manner.
Koichiro Akiyama +2 more
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ABSTRACT The bacterial condensin MukB facilitates proper chromosome segregation in Escherichia coli . A portion of the MukB proteins localize at a specific chromosome region, binding to DNA in a non-sequence-specific manner.
Koichiro Akiyama +2 more
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Molecular and General Genetics MGG, 1994
The nucleotide sequence was determined of the region upstream of the mukB gene of Escherichia coli. Two new genes were found, designated kicA and kicB (killing of cell); the gene order is kicB-kicA-mukB. Promoter activities were detected in the regions immediately upstream of kicB and kicA, but not in front of mukB. Gene disruption experiments revealed
J, Feng +4 more
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The nucleotide sequence was determined of the region upstream of the mukB gene of Escherichia coli. Two new genes were found, designated kicA and kicB (killing of cell); the gene order is kicB-kicA-mukB. Promoter activities were detected in the regions immediately upstream of kicB and kicA, but not in front of mukB. Gene disruption experiments revealed
J, Feng +4 more
openaire +2 more sources
Journal of Molecular Biology, 2009
MukB, a divergent structural maintenance of chromosomes (SMC) protein, is important for chromosome segregation and condensation in Escherichia coli and other gamma-proteobacteria. MukB and canonical SMC proteins share a common five-domain structure in which globular N- and C-terminal regions combine to form an ABC-like ATPase domain. This ATPase domain
Yinyin, Li +3 more
openaire +2 more sources
MukB, a divergent structural maintenance of chromosomes (SMC) protein, is important for chromosome segregation and condensation in Escherichia coli and other gamma-proteobacteria. MukB and canonical SMC proteins share a common five-domain structure in which globular N- and C-terminal regions combine to form an ABC-like ATPase domain. This ATPase domain
Yinyin, Li +3 more
openaire +2 more sources