Results 91 to 100 of about 752,857 (303)

Multistrain models predict sequential multidrug treatment strategies to result in less antimicrobial resistance than combination treatment [PDF]

, 2016
Background Combination treatment is increasingly used to fight infections caused by bacteria resistant to two or more antimicrobials. While multiple studies have evaluated treatment strategies to minimize the emergence of resistant strains for single ...
Ahmad, Amais, Christiansen, Lasse Engbo, Græsbøll, Kaare, Matthews, Louise, Nielsen, Søren Saxmose, Olsen, John Elmerdahl, Toft, Nils, Zachariasen, Camilla   +7 more
core   +4 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Editorial: Multi drug resistant tuberculosis

East African Medical Journal, 2007
No Abstract. The East African Medical Journal Vol. 83 (11) 2006: pp.
openaire   +3 more sources

Exploring the evidence base for national and regional policy interventions to combat resistance [PDF]

, 2015
The effectiveness of existing policies to control antimicrobial resistance is not yet fully understood. A strengthened evidence base is needed to inform effective policy interventions across countries with different income levels and the human health and
Aarestrup, Aarestrup, Ahuja, Aidara-Kane, Alimuddin Zumla, Allegranzi, Allegranzi, Amábile-Cuevas, Anthony D So, Anthony Kessel, Baertlein, Belongia, Belongia, Bushnell, Catley, Catley, Cheng, Coenen, Crowther-Gibson, Dagan, Datema, Davey, David L Heymann, De Boeck, Earnshaw, Emmeline J Buckley, Fazal K Dar, Finkelstein, Fätkenheuer, Gerber, Govin Permanand, Grave, Grave, Grazia Caleo, Grundmann, Hammerum, Hanne Bak Pedersen, Harbarth, Haydar Giha, Hennessy, Henry Lishi Li, Heuer, Holloway, Huttner, Huttner, Jack, Jasper Littmann, John-Arne Røttingen, Jørgen Schlundt, Kariuki, Katakweba, Khalid M Bindayna, Khan, Komolafe, Kümmerer, Little, Luoto, Mandal, Mark Rweyemamu, Marti, McNulty, Mishal Khan, Mitj, Mohammed Shahid, Moyane, Mshana, Nisi, Ogan, Okeke, Okeke, Okeke, Osman A Dar, Parry, Pittet, Pletz, Radley, Ranji, Richard Kock, Rumina Hasan, Silverman, Simonsen, Song, Speksnijder, Spurling, Stephan Harbarth, Vanden Eng, Vernet, Versporten, Versporten, Viberg, Vlieghe, Walt, Xiao, Zingg   +93 more
core   +2 more sources

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Patterns of resistance to first-line anti-Tuberculosis drugs among patients in Abuja, Nigeria: 2009-2012

Journal of Interventional Epidemiology and Public Health
Introduction: Nigeria is among the top ten countries with a high burden of Tuberculosis (TB) worldwide. Drug-resistant TB is a global health burden, but disproportionately higher among TB patients in resource-constrained countries like Nigeria.
Chukwuemeka Anthonia, Ayo Stephen Adebowale, Chukwuma David Umeokonkwo, Muhammad Shakir Balogun, Patrick Nguku, Lovett Lawson   +5 more
doaj   +1 more source

Early results from indirect drug susceptibility test for tubercle bacilli [PDF]

, 1999
The indirect susceptibility test results on L-J medium for tubercle bacilli against streptomycin, isoniazid and rifampicin were read at the end of 2 wk and compared with the results at 4 wk.
Mathew, S, Narayanan, A, Paramasivan, C N, Segaran, R   +3 more
core  

Programmable biomaterials for dynamic and responsive drug delivery [PDF]

, 2016
Biomaterials are continually being designed that enable new methods for interacting dynamically with cell and tissues, in turn unlocking new capabilities in areas ranging from drug delivery to regenerative medicine. In this review, we explore some of the
Almquist, BD, Kiani, MT, Stejskalova, A
core   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Tuberculosis: drug resistance, fitness, and strategies for global control [PDF]

, 2018
Directly observed standardized short-course chemotherapy (DOTS) regimes are an effective treatment for drug susceptible tuberculosis disease. Surprisingly, DOTS has been reported to reduce the transmission of multi-drug resistant tuberculosis, and ...
Böttger, Erik, Springer, Burkhard
core