Results 81 to 90 of about 752,857 (303)

Molecular characterization of drug-resistance genes and dynamics of multidrug-resistant Salmonella spp. in waterfowl: a pre- and post-antibiotic ban surveillance in Guangdong, China from 2013 to 2023

BMC Microbiology
Background Multidrug-Resistant Organism (MDRO) refers to bacteria that are Resistant to three or more types of antibiotics in clinical use. The global health threat posed by multidrug-resistant (MDR) bacterial pathogens and their cross-species ...
Zhican Yang, Wanjia Li, Bingyu Yu, Minfang Liu, Rongxu Li, Jiacheng Zhong, Wanjun Zhu, Yishan Zhang, Jianhong Chen, Jipei Zhang, Jidang Chen   +10 more
doaj   +1 more source

Outsmarting multi-drug resistance in uncertain times [PDF]

JAC-Antimicrobial Resistance, 2020
Graphical Abstract.
openaire   +2 more sources

Antimicrobial resistance gene expression associated with multidrug resistant Salmonella spp. isolated from retail meat in Hanoi, Vietnam [PDF]

, 2017
The purpose of this study was to further characterize the multi-antimicrobial resistance and antibiotic resistance gene expression associated with multi-drug resistance (MDR) in Salmonella spp. isolates from retail meats in Hanoi, Vietnam.
Minh Ngoc Nghiem, Thu Thi Hoai Nguyen, Thuy Thi Bich Vo, Ton Dang Nguyen, Viet Thanh Nguyen   +4 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Prognostic significance of multidrug-resistance protein (MDR-1) in renal clear cell carcinomas: A five year follow-up analysis [PDF]

, 2006
Background: A large number of renal cancer patients shows poor or partial response to chemotherapy and the mechanisms have not been still understood.
Chiara Mignogna, Stefania Staibano, Vincenzo Altieri, Gaetano De Rosa, Giuseppe Pannone, Angela Santoro, Rosanna Zamparese, Massimino D'Armiento, Romualdo Rocchetti, Ernesto Mezza, Mario Nasti, Viviana Strazzullo, Vittorino Montanaro, Massimo Mascolo, Pantaleo Bufo   +14 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Multi-omics advances in understanding cancer drug resistance

Biomedical Technology
Cancer drug resistance presents a significant challenge in modern oncology, necessitating detailed exploration of its underlying mechanisms and the development of effective counterstrategies.
Xuechao Liu, Kunpeng Wei, Enyu Lin, Yi Li, Pengzhen Zhuang, Yanbing Zhou, Guilai Zuo, Zhaojian Niu   +7 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Comparative genomic analysis and multi-drug resistance differences of Acinetobacter baumannii in Chongqing, China

Infection and Drug Resistance, 2019
Ling Pu,1 Zuoyi Jian,2 Fen Pan,3 Yang Geng,4 Miao He,5 Pu Liao1,6 1Key Laboratory of Clinical Laboratory Diagnostics (Ministry of Education of China), College of Laboratory Medicine, Chongqing Medical University, Chongqing, People’s Republic of ...
Pu L, Jian Z, Pan F, Geng Y, He M, Liao P   +5 more
doaj  

Multi-omics dissection of tumor microenvironment-mediated drug resistance: mechanisms and therapeutic reprogramming

Frontiers in Pharmacology
Tumor drug resistance represents a major challenge in contemporary cancer therapeutics, significantly compromising the clinical efficacy of chemotherapy, targeted therapy, and immunotherapy.
Fanghua Chen, Fanghua Chen, Yuandong Fu, Yuandong Fu, Gaigai Bai, Gaigai Bai, Junjun Qiu, Junjun Qiu, Keqin Hua, Keqin Hua   +9 more
doaj   +1 more source