Results 91 to 100 of about 136,187 (283)

Optimization of carbon and energy utilization through differential translational efficiency. [PDF]

open access: yes, 2018
Control of translation is vital to all species. Here we employ a multi-omics approach to decipher condition-dependent translational regulation in the model acetogen Clostridium ljungdahlii.
Al-Bassam, Mahmoud M   +7 more
core   +2 more sources

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu   +14 more
wiley   +1 more source

Chromosome-scale genomes of wild and cultivated Morinda officinalis

open access: yesScientific Data
Morinda officinalis is a renowned medicinal and edible plant native to southern China and northern Vietnam. Its dried roots, known as bajitian are extensively used in traditional Chinese medicine to treat various ailments. Driven by the increasing market
Ruirui Li   +8 more
doaj   +1 more source

Laser‐Microscribed Glass Enables Surface‐Microfluidics‐Facilitated, Affordable, Rapid Cancer Diagnosis

open access: yesAdvanced Functional Materials, EarlyView.
A transparent, laser‐microscribed glass platform enables cancer diagnosis within 1 h—much faster than histology, which takes days, and free from the chemical or contrast risks of MRI or CT scans. The antibody‐functionalized rough glass surface captures viable cancer cells directly from suspension, allowing instant optical readout and offering a rapid ...
Anish Pal   +5 more
wiley   +1 more source

Genome-wide identifications of regulatory variants influencing milk fat percentage in Chinese Holstein cow

open access: yesBMC Genomics
Background Milk fat is a critical economic trait in Holstein cattle; however, the identification of genomic loci associated with milk fat content remains limited, constraining progress in genetic improvement and overall dairy production efficiency.
Changliang Gong   +13 more
doaj   +1 more source

Microphysiological Systems of Lymphatics and Immune Organs

open access: yesAdvanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain   +2 more
wiley   +1 more source

The High-Throughput Analyses Era: Are We Ready for the Data Struggle? [PDF]

open access: yes, 2018
Recent and rapid technological advances in molecular sciences have dramatically increased the ability to carry out high-throughput studies characterized by big data production.
D’Argenio, Valeria
core   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim   +6 more
wiley   +1 more source

Multi-omics data analysis

open access: yes, 2018
Workshop Description: Increasing amounts of high-throughput data sets are collected during the examination of patients, in particular imaging data, and data from genome-wide screening techniques like next-generation sequencing (NGS) or proteomics. The analysis of these complex data sets identifies new[for full text, please go to the a.m. URL]
Löhnhardt, B, Sax, U, Beißbarth, T
openaire   +2 more sources

Mosim: Multi-Omics Simulation in R

open access: yes, 2023
Abstract Motivation As new integrative methodologies are being developed to analyse multi-omic experiments, validation strategies are required for benchmarking. In silico approaches such as simulated data are popular as they are fast and cheap. However, few tools are available for creating synthetic multi-omic data sets.
Martínez-Mira, Carlos   +2 more
openaire   +1 more source

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