Results 21 to 30 of about 136,187 (283)
Depression and suicide risk prediction models using blood-derived multi-omics data [PDF]
, 2019 More than 300 million people worldwide experience depression; annually, ~800,000 people die by suicide. Unfortunately, conventional interview-based diagnosis is insufficient to accurately predict a psychiatric status. We developed machine learning models
Bhak, Jong +19 more
core +1 more source
Experimental and Molecular Medicine, 2023 Although the normal physiological level of oxidative stress is beneficial for maintaining bone homeostasis, imbalance between reactive oxygen species (ROS) production and antioxidant defense can cause various bone diseases.
Heein Yoon +9 more
doaj +1 more source
New Advances， Challenges and Opportunities in Forensic Applications of Microbiomics
Fayixue Zazhi, 2022 The succession of microbiota is closely associated with several essential factors, including race, sex, health condition, lifestyle, postmortem interval, etc., and it has great potential application value in forensic medicine.
LEI Fan-zhang +4 more
doaj +1 more source
Clinical proteomics for precision medicine: the bladder cancer case [PDF]
, 2017 Precision medicine can improve patient management by guiding therapeutic decision based on molecular characteristics. The concept has been extensively addressed through the application of –omics based approaches.
Frantzi, Maria +4 more
core +1 more source
Frontiers in Microbiology, 2023 IntroductionDepression is a common mental disorder that affects approximately 350 million people worldwide. Much remains unknown about the molecular mechanisms underlying this complex disorder. Sigma-1 receptor (Sig-1R) is expressed at high levels in the
Jia-Hao Li +8 more
doaj +1 more source
Machine Learning and Integrative Analysis of Biomedical Big Data. [PDF]
, 2019 Recent developments in high-throughput technologies have accelerated the accumulation of massive amounts of omics data from multiple sources: genome, epigenome, transcriptome, proteome, metabolome, etc. Traditionally, data from each source (e.g., genome)
Choi, Howard +5 more
core +1 more source
Nature Microbiology, 2016 Multi-omic techniques are often seen as the future of microbiome studies. We argue that recent strategies for simplifying complex omic-derived data will need to be combined with improved cultivation techniques to pave the way towards a more targeted approach for understanding microbial communities.
Cristina, Vilanova, Manuel, Porcar
openaire +2 more sources
Integrative Multi-Omics in Biomedical Research [PDF]
Biomolecules, 2021 Genome technologies have revolutionized biomedicine, but the complexity of biological systems cannot be explained by genomics alone [...]
Hill, Michelle M., Gerner, Christopher
openaire +5 more sources
Frontiers in Ecology and Evolution, 2022 The utilization of the ancestry informative markers to disclose the ancestral composition of a certain population and explore the genetic affinities between diverse populations is beneficial to inferring the biogeographic ancestry of unknown individuals ...
Hui Xu +8 more
doaj +1 more source
Multi-Omics Analysis Reveals the Role of Sigma-1 Receptor in a Takotsubo-like Cardiomyopathy Model
Biomedicines, 2023 Takotsubo syndrome (TTS) is a stress-induced cardiomyopathy that presents with sudden onset of chest pain and dyspneic and cardiac dysfunction as a result of extreme physical or emotional stress.
Yi Liu +13 more
doaj +1 more source