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Multicomponent reactions II [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2014
The concept of multicomponent reactions (MCR) [1] has been around in organic chemistry since the very early days. Indeed, the first example known in literature, the Strecker synthesis of α-aminonitriles [2], has been developed into an industrial process for the production of methionine in an annual scale of several hundreds of thousand tons per year ...
Thomas J. J. Müller
doaj   +8 more sources

The Discovery of Novel Antimicrobial Agents through the Application of Isocyanide-Based Multicomponent Reactions [PDF]

open access: yesAntibiotics, 2023
Multicomponent reactions (MCR) have been used to synthesize a wide range of analogs from several classes of heterocyclic compounds, with multifaceted medicinal uses. The synthesis of highly functionalized molecules in a single pot is a unique property of
Sameer Quazi   +3 more
doaj   +2 more sources

Tetrazoles via Multicomponent Reactions [PDF]

open access: yesChemical Reviews, 2019
Tetrazole derivatives are a prime class of heterocycles, very important to medicinal chemistry and drug design due to not only their bioisosterism to carboxylic acid and amide moieties but also to their metabolic stability and other beneficial ...
Constantinos G. Neochoritis   +2 more
semanticscholar   +5 more sources

Cu(OTf)2-catalyzed multicomponent reactions [PDF]

open access: yesBeilstein Journal of Organic Chemistry
This review reports the achievements in copper(II) triflate-catalyzed processes concerning the multicomponent reactions, applied to the synthesis of acyclic and cyclic compounds.
Sara Colombo   +4 more
doaj   +2 more sources

Catalytic Approaches to Multicomponent Reactions: A Critical Review and Perspectives on the Roles of Catalysis. [PDF]

open access: yesMolecules, 2021
In this review, we comprehensively describe catalyzed multicomponent reactions (MCRs) and the multiple roles of catalysis combined with key parameters to perform these transformations.
Neto BAD, Rocha RO, Rodrigues MO.
europepmc   +2 more sources

Multicomponent reactions in nucleoside chemistry [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2014
This review covers sixty original publications dealing with the application of multicomponent reactions (MCRs) in the synthesis of novel nucleoside analogs.
Mariola Koszytkowska-Stawińska   +1 more
doaj   +5 more sources

The Chemistry of Isocyanides, their MultiComponent Reactions and their Libraries [PDF]

open access: goldChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Ivar Ugi   +2 more
openalex   +7 more sources

Isocyanate-based multicomponent reactions. [PDF]

open access: yesRSC Adv
Review on the isocyanate-based multicomponent reaction.
Zavarise C   +3 more
europepmc   +3 more sources

Synthesis of Biologically Active Molecules through Multicomponent Reactions

open access: yesMolecules, 2020
Focusing on the literature progress since 2002, the present review explores the highly significant role that multicomponent reactions (MCRs) have played as a very important tool for expedite synthesis of a vast number of organic molecules, but also ...
Daniel Insuasty   +4 more
doaj   +2 more sources

Steroid diversification by multicomponent reactions [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2019
Reports on structural diversification of steroids by means of multicomponent reactions (MCRs) have significantly increased over the last decade. This review covers the most relevant strategies dealing with the use of steroidal substrates in MCRs ...
Leslie Reguera   +3 more
doaj   +5 more sources

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