Results 11 to 20 of about 19,915 (242)

Multicomponent Reactions for the Synthesis of Active Pharmaceutical Ingredients [PDF]

open access: yesPharmaceuticals, 2022
Multicomponent reactions 9i.e., those that engage three or more starting materials to form a product that contains significant fragments of all of them), have been widely employed in the construction of compound libraries, especially in the context of ...
Ángel Cores   +3 more
doaj   +2 more sources

Bio-Catalysis in Multicomponent Reactions [PDF]

open access: yesMolecules, 2020
Enzyme catalysis is a very active research area in organic chemistry, because biocatalysts are compatible with and can be adjusted to many reaction conditions, as well as substrates.
Ndze Denis Jumbam, Wayiza Masamba
doaj   +3 more sources

Isocyanate-based multicomponent reactions. [PDF]

open access: yesRSC Adv
Review on the isocyanate-based multicomponent reaction.
Zavarise C   +3 more
europepmc   +3 more sources

Steroid diversification by multicomponent reactions [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2019
Reports on structural diversification of steroids by means of multicomponent reactions (MCRs) have significantly increased over the last decade. This review covers the most relevant strategies dealing with the use of steroidal substrates in MCRs ...
Leslie Reguera   +3 more
doaj   +4 more sources

Multicomponent reactions in nucleoside chemistry [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2014
This review covers sixty original publications dealing with the application of multicomponent reactions (MCRs) in the synthesis of novel nucleoside analogs.
Mariola Koszytkowska-Stawińska   +1 more
doaj   +3 more sources

Multicomponent reactions [PDF]

open access: yesBeilstein Journal of Organic Chemistry, 2011
Thomas J. J. Müller
doaj   +3 more sources

5-Ethoxy-1-(4-methoxyphenyl)-5-methyl-3-phenylimidazolidine-2,4-dione

open access: yesMolbank, 2021
The title compound is a hydantoin derivative that has been synthesized through a three-component reaction of ethyl pyruvate, p-anisidine and phenyl isocyanate.
Xabier del Corte   +4 more
doaj   +1 more source

Electrochemical Synthesis of Sulfonamides in Single‐Pass Flow

open access: yesChemElectroChem, 2023
An electrochemical multicomponent synthesis of sulfonamides at room temperature in single‐pass flow is presented. In contrast to batch‐type electrolysis, an undivided flow cell setup with a stainless‐steel cathode and either a boron‐doped diamond (BDD ...
Johannes Schneider   +2 more
doaj   +1 more source

Tetrazoles via Multicomponent Reactions [PDF]

open access: yesChemical Reviews, 2019
Tetrazole derivatives are a prime class of heterocycles, very important to medicinal chemistry and drug design due to not only their bioisosterism to carboxylic acid and amide moieties but also to their metabolic stability and other beneficial physicochemical properties.
Constantinos G. Neochoritis   +2 more
openaire   +3 more sources

Exploiting the Nucleophilicity of the Nitrogen Atom of Imidazoles: One-Pot Three-Component Synthesis of Imidazo-Pyrazines

open access: yesMolecules, 2019
A novel one-pot multicomponent reaction to synthesize substituted imidazopyrazines is described. In brief, 1H-(imidazol-5-yl)-N-substituted methanamines react with aldehydes and isocyanides in methanol at room temperature to give imidazopyrazine ...
Ubaldina Galli   +7 more
doaj   +1 more source

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